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Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Researchers at the University of Maryland School of Medicine's (UMSOM) Center for Precision Disease Modeling identified how a specific protein in SARS-CoV-2, the virus responsible for COVID-19, damages heart tissue. They then used a drug to reverse the toxic effects of that protein on the heart.

8 Nov 2022

Experts analyze the intensity of use and addiction of e-cigarettes

A new analysis published in JAMA Network Open by investigators at Massachusetts General Hospital (MGH) in collaboration with a retired UCSF professor reveals ongoing and worsening adolescent e-cigarette addiction in the United States.

8 Nov 2022

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists.

8 Nov 2022

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

Restoring blood flow to the legs, whether through bypass surgery or a less invasive artery-opening procedure with a stent, reduced pain and improved quality of life for people with peripheral artery disease (PAD), according to preliminary, late-breaking research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

New medication lowers triglyceride levels, yet does not decrease cardiovascular risk in people with Type 2 diabetes

A new medication, pemafibrate, lowered triglyceride levels among adults with Type 2 diabetes yet did not decrease their cardiovascular risk, according to late-breaking science research presented today at the American Heart Association's Scientific Sessions 2022.

7 Nov 2022

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

A genetic test known as chromosomal microarray analysis (CMA) could help identify the cause of sudden infant death syndrome (SIDS) or its counterpart in older children, known as sudden unexplained death in childhood (SUDC), finds a study led by Boston Children's Hospital.

7 Nov 2022

Researchers provide insights on how to overcome resistance in cancer therapy

The latest developmental drugs, particularly for the use in oncology, rely on the targeted degradation of harmful pathogenic proteins.

3 Nov 2022

Understanding the brain correlates of dissociative disorders

Trauma can cause dissociative symptoms - such as having an out-of-body experience, or feeling emotionally numb - that may help an individual cope in the short term but can have negative impacts if the symptoms persist for a long period of time.

3 Nov 2022

Parental discord linked to children's genetic risk for alcohol problems

Parents can transmit a genetic risk for alcohol problems to their children not only directly, but also indirectly via genetically influenced aspects of the home environment, such as marital discord or divorce, according to a Rutgers researcher.

3 Nov 2022

Researchers corroborate the importance of exercise for cognitive function

Accumulating evidence finds that exercise can improve brain function and delay or prevent the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

2 Nov 2022

Study highlights the importance of poverty in criminal conviction

A significant reduction in childhood poverty could cut criminal convictions by almost a quarter, according to a study conducted in Brazil. An article on the study is published in Scientific Reports. The researchers used an innovative approach involving an analysis of 22 risk factors that affect human development and interviews with 1,905 children at two points – a first interview to form a baseline (mean age 10.3) and a follow-up interview seven years later (mean age 17.8).

2 Nov 2022

Study identifies a root cause of chronic heart failure following a heart attack

A multi-institution study led by Rohan Dharmakumar, PhD, of Indiana University School of Medicine, has identified that iron drives the formation of fatty tissue in the heart and leads to chronic heart failure in about fifty percent of heart attack survivors.

1 Nov 2022

Rutgers study finds substantial inequities in access to specialty epilepsy care in New Jersey

For millions of Americans who suffer from epilepsy, advanced monitoring is essential for diagnosis and effective treatment. But in New Jersey, accessing these services is difficult for patients from racial and ethnic minority groups, according to a Rutgers study.

1 Nov 2022

Cohort study determines how often COVID-19 symptoms recurred

Researchers at University of California San Diego School of Medicine, with colleagues from the ACTIV-2 trial, part of the U.S. government's response to COVID-19, investigated whether symptoms of COVID-19 recurred following a two-day symptom-free period in persons who did not receive any treatment for the disease.

1 Nov 2022

Medical School News and Research

Study identifies a potential pharmacological target for treating COVID-19-associated heart failure

Experts analyze the intensity of use and addiction of e-cigarettes

Study: Fenofibrate not a useful strategy for decreasing COVID-19 severity

Restoring blood flow to the legs reduces pain, improves quality of life for people with peripheral artery disease

New medication lowers triglyceride levels, yet does not decrease cardiovascular risk in people with Type 2 diabetes

Chromosomal microarray analysis could help identify the cause of SIDS or SUDC in older children

Researchers provide insights on how to overcome resistance in cancer therapy

Understanding the brain correlates of dissociative disorders

Parental discord linked to children's genetic risk for alcohol problems

Researchers corroborate the importance of exercise for cognitive function

Study highlights the importance of poverty in criminal conviction

Study identifies a root cause of chronic heart failure following a heart attack

Rutgers study finds substantial inequities in access to specialty epilepsy care in New Jersey

Cohort study determines how often COVID-19 symptoms recurred

IHV researchers receive $7.5 million to control cancer among people living with HIV in sub-Saharan Africa

Artificial intelligence-based method may help predict early-stage melanoma recurrence

Study provides new insights into genetic form of frontotemporal dementia

ADOS testing not required for ASD diagnosis by developmental-behavioral pediatricians

Rutgers physicians take newer approach in successfully treating a mysterious disease

Lancaster University to be part of building malaria modeling capacity in Sub-Saharan Africa

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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