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New suggests different approach to eczema treatment

Eczema affects about 17 percent of children in developed countries and is often the gateway to food allergy and asthma, initiating an "atopic march" toward broader allergic sensitization.

6 Mar 2018

Research shows how viruses inactivate immune system, causing cancer

It's no new news that viruses cause cancer. For example, human papillomavirus causes almost all of the more than 500,000 annual worldwide cases of cervical cancer.

2 Mar 2018

UNIGE researchers discover why premature cell division promotes tumor formation

The accumulation of mutations in the human genome is at the origin of cancers, as well as the development of resistance to treatments. The Cyclin E and Myc genes are active in the control of cell division.

28 Feb 2018

Repurposing leukemia drugs may be effective approach for treating metastatic melanoma patients

Data from a new study led by University of Kentucky Markey Cancer Center researchers shows that repurposing drugs used to treat leukemia has promise for preventing melanoma metastasis.

26 Feb 2018

Hamilton Robotics Launch ID NIMBUS® for Forensic Genomics Applications

Hamilton Robotics announce the release of the ID NIMBUS® assay ready workstation, specifically pre-configured and qualified to automate post-PCR sample processing using the Verogens renowned ForenSeq DNA Signature Prep Kit.

From Hamilton Company 26 Feb 2018

Scientists reveal new insights into mechanism of gene regulation by 'magic spot'

Using an innovative crystallization technique for studying three-dimensional structures of gene transcription machinery, an international team of researchers, led by scientists at Penn State, has revealed new insights into the long debated action of the "magic spot"--a molecule that controls gene expression in Eschericahia coli and many other bacteria when the bacteria are stressed.

24 Feb 2018

Research opens up new avenue to minimize risks of transplants

A bone marrow transplant is often the only therapy available to save leukemia patients, but the risk of complications is high. In spite of devoting considerable time and effort to finding a suitable donor, nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50% of cases the intestines.

21 Feb 2018

Penn study sheds new light on immune cell identity

Almost all cells in the human body have identical DNA sequences, yet there are 200-plus cell types with different sizes, shapes, and chemical compositions. Determining what parts of the genome are read to make protein and which are silenced is orchestrated by proteins called transcription factors.

21 Feb 2018

Scientists explore connection between bad sleep habits and stiff blood vessels

What do bad sleep habits and stiff blood vessels have in common? Nothing good, say scientists exploring what appears to be a direct connection between a circadian clock that isn't working as it should and an enzyme that promotes inflammation working overtime.

20 Feb 2018

Key proteins could help in controlling the risk of osteoarthritis during aging, Study finds

New study reveals that FOXO proteins help maintain healthy cells in the cartilage of the joints.

15 Feb 2018

TSRI study reveals potential strategy to prevent, treat osteoarthritis during aging

More than 30 million Americans suffer from osteoarthritis making it one of the most common age-related diseases.

15 Feb 2018

Pioneering research could provide novel insight into how genomic information is read

Pioneering new research could offer a fascinating new insight into how genomic information is read. The human genome contains thousands of genes, but to get the information from a gene requires it to be copied.

13 Feb 2018

Scientists use novel epigenetic-centered techniques to inhibit cancer metastases

In one of the first successes of its kind, researchers from Case Western Reserve University School of Medicine and six other institutions have inhibited the spreading of cancer cells from one part of the body to another.

12 Feb 2018

Using CRISPR To Produce Induced Pluripotent Stem Cells

An interview with Dr. Sheng Ding about using a modified version of the CRISPR-Cas9 system to produce induced pluripotent stem cells.

9 Feb 2018

Novel grape-derived compounds could be developed as therapeutic agents for treatment of depression

In a study to be published online February 2 in Nature Communications, scientists from the Icahn School of Medicine at Mount Sinai describe an extensive analysis of novel grape-derived compounds, dihydrocaffeic acid (DHCA) and malvidin-3'-O-glucoside (Mal-gluc),which might be developed as therapeutic agents for the treatment of depression.

2 Feb 2018

Researchers identify cause of severe genetic disease

Mutations in the p63 protein lead to a number of disorders, but none is as severe as the AEC syndrome. Scientists at Goethe University Frankfurt in collaboration with a research group from the University of Naples Federico II have now discovered that this syndrome resembles diseases such as Alzheimer's, Parkinson's or ALS more closely than it does other p63-based syndromes.

2 Feb 2018

New ChIPseq kit is optimized for fresh and frozen tissue samples

The new, high-performance Chromatrap ChIP-Seq kit (v.1.5) is optimized to work from fresh and frozen extracted tissue, as well as cell lines.

From Chromatrap® - Porvair Sciences Ltd 2 Feb 2018

Researchers take first step in generating artificial adrenal gland

In a new study, published in Cell Reports, researchers from the William Harvey Research Institute at Queen Mary University of London used cells derived from urine to take the first step in generating an artificial adrenal gland.

30 Jan 2018

Computational approach can help identify chemoresistant potential targets in cancer stem cells

In cancer, one of the most important features is the methylation of deoxycytosine to form 5-methylcytosine (5mC). DNA methylation is a process by which methyl groups (structural units of organic compounds consisting of three hydrogen atoms bonded to a carbon atom) are added to the DNA molecule.