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HHMI scientists identify stem cells that give rise to functional liver cells

Howard Hughes Medical Institute scientists have identified stem cells in the liver that give rise to functional liver cells. The work solves a long-standing mystery about the origin of new cells in the liver, which must constantly be replenished as cells die off, even in a healthy organ.

6 Aug 2015

Penn research reveals additional pathway for origin of colon cancer

Cancer researchers already know of some oncogenes and other factors that promote the development of colon cancers, but they don't yet have the full picture of how these cancers originate and spread. Now researchers from the Perelman School of Medicine at the University of Pennsylvania have illuminated another powerful factor in this process.

6 Aug 2015

Scientists use highly specialized X-ray crystallography technique to solve protein structure of HIFs

In a collaborative study between Sanford Burnham Prebys Medical Discovery Institute and the Argonne National Laboratory, scientists have used a highly specialized X-ray crystallography technique to solve the protein structure of hypoxia-inducible factors (HIFs), important regulators of a tumor's response to low oxygen (hyopoxia).

6 Aug 2015

Researchers show how realistic environments affect growth of cancer tumors in bones

Researchers at Rice University and University of Texas MD Anderson Cancer Center have developed a way to mimic the conditions under which cancer tumors grow in bones.

6 Aug 2015

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

Half of patients referred to a specialist centre with a diagnosis of chronic inflammatory demyelinating polyneuropathy do not actually have the condition, report researchers.

5 Aug 2015

TSRI study shows single injection of blebbistatin drug prevents methamphetamine relapse in animal models

Recovering addicts often grapple with the ghosts of their addiction—memories that tempt them to relapse even after rehabilitation and months, or even years, of drug-free living.

5 Aug 2015

New biosensors detect efficient microbial workers that produce chemical, pharmaceutical commodities

Super productive factories of the future could employ fleets of genetically engineered bacterial cells, such as common E. coli, to produce valuable chemical commodities in an environmentally friendly way.

5 Aug 2015

Researchers find CD163 protein limits muscle repair after ischemic injury

Researchers have identified a protein produced by white blood cells that puts the brakes on muscle repair after injury. By removing the protein CD163 from mice, scientists at Emory University School of Medicine could boost muscle repair and recovery of blood flow after ischemic injury (damage caused by restriction of blood flow).

5 Aug 2015

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Joslin scientists have advanced understanding of how the cellular repair process is impaired in type 1 diabetes, which can cause cell death and lead to complications. The findings appear in the August issue of Cell Metabolism.

5 Aug 2015

Brain's electrical activity may be more primary factor in memory solidification

The permanence of memories has long thought to be mediated solely by the production of new proteins. However, new research from the University of Alberta has shown that the electrical activity of the brain may be a more primary factor in memory solidification.

5 Aug 2015

Rice University scientists identify genetic mechanism that allows bacteria to resist antibiotics

Rice University scientists are developing strategies to keep germs from evolving resistance to antibiotics by heading them off at the pass.

5 Aug 2015

Molecular packaging enhances cancer drug’s effectiveness at destroying tumors

Researchers have packaged a widely used cancer drug into nanoparticles, more than doubling its effectiveness at destroying tumors.

5 Aug 2015

IP10 levels linked to HBsAg decline during TDF treatment

Baseline serum interferon-inducible protein 10 levels predict hepatitis B surface antigen reduction in patients with hepatitis B e antigen-negative chronic hepatitis B virus infection treated with tenofovir disoproxil fumarate, findings indicate.

4 Aug 2015

G7 Therapeutics, MorphoSys collaborate on novel antibody therapeutics targeting GPCRs and ion channels

MorphoSys AG and G7 Therapeutics AG announced today that they have signed an agreement to collaborate on novel antibody therapeutics targeting G protein-coupled receptors and potentially other disease-related transmembrane proteins such as ion channels.

4 Aug 2015

Study reveals new gene that plays crucial role in ASD

A study carried out by the Laboratoire Neurobiologie des Interactions Cellulaires et Neurophysiopathologie (CNRS/Aix-Marseille Université), in collaboration with clinicians from Marseilles Public Hospitals (AP-HM) and scientists from the Salk Institute in San Diego (US), has revealed a new gene that plays a crucial role during early development in humans and whose under-expression may induce certain autistic traits.

4 Aug 2015

Breakthroughs against Plasmodium falciparum pave way for latest advancement

When the highly-influential European Medicines Agency announced its recommendation to approve what could be the world's first licensed vaccine against malaria in infants and children, there was much celebrating in the research community at NYU Langone Medical Center.

4 Aug 2015

Clinical dietitian suggests tips to help parents ensure healthy nutrition for children

Back to school means getting back into a routine that helps students achieve success in the new school year. Start the year off on solid footing by making good nutrition part of your child's schedule. Multiple studies have shown that good nutrition, improved hydration and proper sleep play a huge role in academic success.

4 Aug 2015

Researchers awarded NIH grant to revolutionize TB treatment

Stop Jeff North, Ph.D., if you've heard this one before: an indole-based drug and a tuberculosis protein meet in a laboratory. There's a brief interaction, then the drug skates merrily away while the protein is nowhere to be found.

4 Aug 2015

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

Ethiopians have lived at high altitudes for thousands of years, providing a natural experiment for studying human adaptations to low oxygen, a condition known as hypoxia. One factor that may enable Ethiopians to tolerate high altitudes and hypoxia is the endothelin receptor type B (EDNRB) gene.

4 Aug 2015

Stress responder plays critical, early step in repairing DNA damage

DNA damage increases the risk of cancer, and researchers have found that a protein, known to rally when cells get stressed, plays a critical, early step in its repair.

4 Aug 2015

Protein C News and Research

HHMI scientists identify stem cells that give rise to functional liver cells

Penn research reveals additional pathway for origin of colon cancer

Scientists use highly specialized X-ray crystallography technique to solve protein structure of HIFs

Researchers show how realistic environments affect growth of cancer tumors in bones

Chronic inflammatory demyelinating polyneuropathy commonly misdiagnosed

TSRI study shows single injection of blebbistatin drug prevents methamphetamine relapse in animal models

New biosensors detect efficient microbial workers that produce chemical, pharmaceutical commodities

Researchers find CD163 protein limits muscle repair after ischemic injury

Findings by Joslin scientists may lead to early detection, treatment of complications in type 1 diabetes

Brain's electrical activity may be more primary factor in memory solidification

Rice University scientists identify genetic mechanism that allows bacteria to resist antibiotics

Molecular packaging enhances cancer drug’s effectiveness at destroying tumors

IP10 levels linked to HBsAg decline during TDF treatment

G7 Therapeutics, MorphoSys collaborate on novel antibody therapeutics targeting GPCRs and ion channels

Study reveals new gene that plays crucial role in ASD

Breakthroughs against Plasmodium falciparum pave way for latest advancement

Clinical dietitian suggests tips to help parents ensure healthy nutrition for children

Researchers awarded NIH grant to revolutionize TB treatment

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

Stress responder plays critical, early step in repairing DNA damage

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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