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What we know and don’t know about memory loss after surgery

Two years ago, Dr. Daniel Cole's 85-year-old father had heart bypass surgery. He hasn't been quite the same since.

12 Apr 2018

Surgeons identify rates of C. difficile infection in patients undergoing common colon operations

Clostridium difficile infection is the most common hospital-acquired infection and a significant cause of increased hospital stay and cost for patients and payors alike.

11 Apr 2018

Experimental peptide drug shows promise against acute myeloid leukemia

In a study published online today in Science Translational Medicine, Albert Einstein College of Medicine researchers report that an experimental peptide drug shows promise against the often-lethal cancer acute myeloid leukemia and describe how the drug works at the molecular level.

11 Apr 2018

Life-saving STB and B-Con techniques need to become as familiar as CPR

Nearly 60,000 people die from bleeding each year, and though injuries that result in extreme blood loss have long been a sight all too common in areas like West Philadelphia, the national spotlight has certainly shone upon the issue of late.

11 Apr 2018

Researcher explores how children develop immunity to malaria as they grow older

Across the world, over 200 million cases of malaria and nearly 500,000 deaths from the disease occur annually--more than 90 percent of which happen in Africa. Children in Africa can be diagnosed with malaria two or three times a year, a rate that decreases as they become older and develop immunity. But the way children generate and maintain this immunity remains a mystery.

11 Apr 2018

Ludwig scientists develop and test individualized ovarian cancer vaccine

A Ludwig Cancer Research study has shown that an entirely new type of personalized cancer vaccine induces novel, potent and clinically effective immune responses in patients receiving a combination of standard therapies for recurrent, stage III and IV ovarian cancer.

11 Apr 2018

New cancer vaccine yields promising results in clinical study

A new type of cancer vaccine has yielded promising results in an initial clinical trial conducted at the Perelman School of Medicine at the University of Pennsylvania and the Abramson Cancer Center of the University of Pennsylvania.

11 Apr 2018

Is there such a thing as normal aging?

For 93-year-old Joseph Brown, the clearest sign of aging was his inability the other day to remember he had to have his pants unzipped to pull them on.

11 Apr 2018

Traumatic brain injury associated with higher risk of dementia

The risk of dementia, including Alzheimer's, was significantly higher in people who had experienced a traumatic brain injury (TBI) than with people who had no history of TBI, according to one of the largest studies to date on that association.

11 Apr 2018

Biomarker panel can guide future therapeutic decisions for glioma patients

In an article published April 10th in the journal Cell Reports, researchers at the University of São Paulo describe a biomarker panel that could tell physicians which patients diagnosed with glioma, a type of brain cancer, will tend to progress to a more aggressive form of the disease in the event of relapse.

10 Apr 2018

Research identifies link between rare gene variants and survival after blood and marrow transplant

Blood and marrow transplant, or BMT, is a lifesaving and effective treatment for many patients, but the procedure can cause serious and life-threatening complications.

10 Apr 2018

Data-driven tool defines risk stages for children with chronic kidney disease

Experts in pediatric kidney disease have published a new staging system to help doctors better predict the length of time until a child with chronic kidney disease (CKD) will need to undergo a kidney transplant or start receiving dialysis. Although this type of prognostic guide exists for adults, this is the first such tool specific to children.

10 Apr 2018

Scientists find new molecular target to treat idiopathic pulmonary fibrosis

Scientists searching for a therapy to stop the deadly and mostly untreatable lung disease, idiopathic pulmonary fibrosis (IPF), found a new molecular target that slows or stops the illness in preclinical laboratory tests.

10 Apr 2018

UT Southwestern's Dr. Nijhawan selected for ASCI's 2018 Seldin-Smith Award

UT Southwestern's Dr. Deepak Nijhawan became a co-recipient of the 2018 Donald Seldin-Holly Smith Award for Pioneering Research. The award recognizes Dr. Nijhawan's work identifying targets for cancer treatment.

10 Apr 2018

Cancer risk increases with longer wait time for diagnostic testing

The longer a patient with a positive screening result waits for diagnostic testing, the worse their cancer outcomes may become, according to a literature review of breast, cervical, colorectal, and lung studies in the journal CA led by researchers at the Perelman School of Medicine at the University of Pennsylvania.

10 Apr 2018

Patients with high-risk clinical features have greater risk for acute aortic dissection

Patients with one or more high-risk clinical features (tearing pain, hypotension, pulse deficit, neurologic deficit, new murmur) should be considered high risk for acute aortic dissection.

10 Apr 2018

New project identifies effective community-based strategies to prevent childhood obesity

To improve success rates and combat continuing disparities in the fight against childhood obesity, the Childhood Obesity Declines Project is taking a systematic approach to studying community-based strategies that have led to declining obesity rates.

10 Apr 2018

New blood test may predict future heart disease risk

Despite heart disease and type 2 diabetes being among the leading causes of death in the U.S., the mechanisms leading to and linking these two diseases remain incompletely understood.

10 Apr 2018

Sex and racial gaps for cardiac rehabilitation referral could be reduced

Substantial sex and racial gaps exist for cardiac rehabilitation referral at hospital discharge, especially among females, African-Americans, Hispanic and Asian patients leading to less favorable outcomes and/or survival rates.

10 Apr 2018

Researchers suggest alternative therapy for heart attack patients with beta blocker intolerance

Beta blockers have become a prescription drug staple for recovering heart attack patients. However, these blood pressure-reducing medications cannot be tolerated by many patients who are at higher risk for developing cardiovascular disease, including those with chronic obstructive pulmonary disease and asthma, the elderly, and diabetics.

10 Apr 2018