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Full assembly of human chromosome 8 reveals novel genes, disease risks

The full assembly of human chromosome 8 is reported this week in Nature. While on the outside this chromosome looks typical, being neither short nor long or distinctive, its DNA content and arrangement are of interest in primate and human evolution, in several immune and developmental disorders, and in chromosome sequencing structure and function generally.

8 Apr 2021

IRB Barcelona researchers find the Achilles heel of some lung tumors

In cancer, personalized medicine takes advantage of the unique genetic changes in an individual tumor to find its vulnerabilities and fight it.

8 Apr 2021

Researchers characterize genetic intra-tumor heterogeneity across cancer genomes

Researchers at the Francis Crick Institute, as part of an international collaboration of scientists through the Pan-Cancer Analysis of Whole Genomes Consortium, have analyzed the whole genomes of tumor samples from over 2,600 patients with different types of cancer.

7 Apr 2021

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

A team of scientists from the University of California Santa Cruz, USA, recently identified a novel variant (B.1.x) of SARS-CoV-2 that might be circulating in at least 20 US states and six countries globally.

7 Apr 2021

COVID-19 pandemic highlights the key role of biodiversity collections

Events such as the COVID-19 pandemic have highlighted the crucial role played by biodiversity collections in enabling rapid responses to crises and in facilitating ongoing research across numerous fields.

7 Apr 2021

Tissue architecture impacts the evolutionary course of cancer

Tumors are genetically diverse with different mutations arising at different times throughout growth and development.

6 Apr 2021

Natural selection and adaptation of SARS-CoV-2 in mammals

Researchers of the Hubei University of Medicine, China, have analyzed several mutations in different variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) from mammal species that suggest natural selection and host adaptation are occurring in the virus.

6 Apr 2021

UCL scientists use AI to identify three new multiple sclerosis subtypes

Scientists at UCL have used artificial intelligence (AI) to identify three new multiple sclerosis (MS) subtypes. Researchers say the groundbreaking findings will help identify those people more likely to have disease progression and help target treatments more effectively.

6 Apr 2021

Research shows efficacy of early warning signals for disease emergence amid COVID-19

The study, published on the pre-print server medRxiv, shows that early warning signals (EWS) provide expected trends, predicting future epidemics and disease emergence.

6 Apr 2021

Can universal vaccines and treatments against future SARS-CoV-2 variants be developed?

A team of researchers from Saudi Arabia and Spain recently quantified the rapid evolution of SARS-CoV-2 by tracking the mutations of the virus globally, focusing on the receptor-binding domain (RBD) of the virus’s spike protein, which determines its infectivity.

5 Apr 2021

SARS-CoV-2 cryptic transmission modeling shows emergence of first wave in US and Europe

To analyze this cryptic transmission phase and the first wave of the pandemic that ensued, researchers from Italy, UK, and the US used a data-driven, spatial, stochastic, and age-structured epidemic model. They developed a mechanistic understanding of the evolution of the epidemic and estimated the time required for local transmission in various states and countries. The model developed by the team offers a statistical idea of SARS-CoV-2 introductions across European countries and many states in the US.

5 Apr 2021

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

A new analysis of the entire genetic makeup of more than 53,000 people offers a bonanza of valuable insights into heart, lung, blood and sleep disorders, paving the way for new and better ways to treat and prevent some of the most common causes of disability and death.

5 Apr 2021

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

Even though a comparative study on the genomic sequences of SARS-CoV, MERS-CoV, and SARS-CoV-2 is available, there is a gap in the research in regards to the comparison between four types of coronaviruses, namely, SARS-CoV, MERS-CoV, BAT-CoV, and SARS-CoV-2. A new study, which deals with the genomic comparison between the sequence of the above-stated four types of coronaviruses, has been published in the Journal of Medical Virology.

2 Apr 2021

New wireless system can restore communication and mobility in people with paralysis

Brain-computer interfaces (BCIs) are an emerging assistive technology, enabling people with paralysis to type on computer screens or manipulate robotic prostheses just by thinking about moving their own bodies.

2 Apr 2021

New genetic link to male infertility found

The findings published in eLife show that men with this unstable subtype of the Y chromosome have a significantly increased risk of genomic rearrangements.

1 Apr 2021

Study sheds new light on the evolution of mammalian brain size

A new study has revealed a surprising lack of support for widely-held explanations of why some mammals evolve larger brains than expected for their body size.

1 Apr 2021

COVID-19 surges are driven by appearance of new SARS-CoV-2 variants, genome sequencing shows

Genome sequencing of thousands of SARS-CoV-2 samples shows that surges of COVID-19 cases are driven by the appearance of new coronavirus variants, according to new research from the School of Veterinary Medicine at the University of California, Davis published April 1 in Scientific Reports.

1 Apr 2021

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

The College of American Pathologists (CAP), in collaboration with five other societies, developed a draft evidence-based clinical practice guideline that aims to optimize PD-L1 testing for patients with non-small cell lung cancer (NSCLC) who are being considered for immunooncology therapy.

1 Apr 2021

Asymmetrical vaccine distribution could promote vaccine evading mutations in SARS-CoV-2

Researchers have investigated the ultimate influence of unequal vaccine distribution by mathematical modeling, revealing the critical role of fair distribution in future COVID-19 containment strategy.

31 Mar 2021

SwRI to design machine learning algorithms for integrated traffic management

Southwest Research Institute, in collaboration with Vanderbilt University, is developing machine learning algorithms to help the Tennessee Department of Transportation (TDOT) coordinate traffic management and incident response along portions of Interstate 24 in the rapidly growing Nashville region.

31 Mar 2021

Evolution News and Research

Full assembly of human chromosome 8 reveals novel genes, disease risks

IRB Barcelona researchers find the Achilles heel of some lung tumors

Researchers characterize genetic intra-tumor heterogeneity across cancer genomes

Researchers identify novel SARS-CoV-2 variant unregistered on genomic sequence databases

COVID-19 pandemic highlights the key role of biodiversity collections

Tissue architecture impacts the evolutionary course of cancer

Natural selection and adaptation of SARS-CoV-2 in mammals

UCL scientists use AI to identify three new multiple sclerosis subtypes

Research shows efficacy of early warning signals for disease emergence amid COVID-19

Can universal vaccines and treatments against future SARS-CoV-2 variants be developed?

SARS-CoV-2 cryptic transmission modeling shows emergence of first wave in US and Europe

Genome analysis of more than 53,000 people offers valuable insights into dangerous diseases

Comparative study of SARS, MERS, BAT‐SARS, and SARS-CoV-2

New wireless system can restore communication and mobility in people with paralysis

New genetic link to male infertility found

Study sheds new light on the evolution of mammalian brain size

COVID-19 surges are driven by appearance of new SARS-CoV-2 variants, genome sequencing shows

Evidence-based clinical practice guideline aims to optimize PD-L1 lung tumor testing

Asymmetrical vaccine distribution could promote vaccine evading mutations in SARS-CoV-2

SwRI to design machine learning algorithms for integrated traffic management

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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