Genetic Engineering News and Research

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Understanding the role of dsRNA in antiviral host defense systems

Animals, insects, and plants use a variety of sensing mechanisms to detect invading pathogens such as viruses. One complex and effective antiviral defense system they share is based on recognition of double-stranded RNA, often produced when a virus invades a host cell.

20 May 2013

Researchers use new analysis method to determine genes that result in cell death

Lethal and rescuer genes are defined as genes that when inactivated result in cell death or enhanced cell growth, respectively. The ability to identify these genes in large-scale automated screening campaigns could lead to the discovery of valuable new drug targets.

17 May 2013

Study: Breastfeeding can prevent the development of ADHD later in childhood

Breastfeeding has a positive impact on the physical and mental development of infants. A new study suggests that breastfeeding may protect against the development of attention-deficit/hyperactivity disorder (ADHD) later in childhood.

15 May 2013

Research findings may pave way to new treatment for Alzheimer's disease in humans

A drug developed by scientists at the Salk Institute for Biological Studies, known as J147, reverses memory deficits and slows Alzheimer's disease in aged mice following short-term treatment.

14 May 2013

Noninvasive imaging tests may play bigger role in diabetes management

New approaches to applying noninvasive imaging tests such as computed tomography, magnetic resonance, and positron emission tomography may play a bigger role in evaluating and managing patients with diabetes.

14 May 2013

Study: Tomatoes and soy may be effective in preventing prostate cancer

Tomatoes and soy foods may be more effective in preventing prostate cancer when they are eaten together than when either is eaten alone, said a University of Illinois study.

10 May 2013

Progenitor cells remain highly dynamic in the adult brain

By monitoring the behavior of a class of cells in the brains of living mice, neuroscientists at Johns Hopkins discovered that these cells remain highly dynamic in the adult brain, where they transform into cells that insulate nerve fibers and help form scars that aid in tissue repair.

10 May 2013

Complex network of molecules controls formation and activity of neuronal connections

Environment moulds behaviour - and not just that of people in society, but also at the microscopic level. This is because, for their function, neurons are dependent on the cell environment, the so-termed extracellular matrix.

7 May 2013

Scientists create animal models by altering specific genes associated with a given disease

Whitehead Institute Founding Member Rudolf Jaenisch, who helped transform the study of genetics by creating the first transgenic mouse in 1974, is again revolutionizing how genetically altered animal models are created and perhaps even redefining what species may serve as models.

6 May 2013

Experts report new outbreaks and increased spread of Cassava Brown Streak Disease

Cassava experts are reporting new outbreaks and the increased spread of Cassava Brown Streak Disease or CBSD, warning that the rapidly proliferating plant virus could cause a 50 percent drop in production of a crop that provides a significant source of food and income for 300 million Africans.

6 May 2013

Study: Combination of chemotherapy and nerve-protecting agents can prevent anemia

Cancer chemotherapy can cause peripheral neuropathy-nerve damage often resulting in pain and muscle weakness in the arms and legs. Now, researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that chemo also induces an insidious type of nerve damage inside bone marrow that can cause delays in recovery after bone marrow transplantation.

6 May 2013

Novel screening method for identifying inhibitors of EZH2 methyltransferase

Tumor repressor genes, which inhibit tumor formation, can be "turned off" due to undesirable molecular changes affecting the chromosomes on which the genes reside. Understanding and being able to control these alterations could lead to new approaches for activating or inactivating genes linked to cancer.

5 May 2013

Violence and Gender: New refereed journal delves into gender basis of violence

Delving into controversial and unsettling subjects such as the gender basis of violence, the new refereed journal Violence and Gender, launching in fall 2013, will explore the difficult issues that are vital to threat assessment and prevention of the epidemic of violence.

26 Apr 2013

Edible malarial vaccine may work against other viral and bacterial infections

Can scientists rid malaria from the Third World by simply feeding algae genetically engineered with a vaccine? That's the question biologists at UC San Diego sought to answer after they demonstrated last May that algae can be engineered to produce a vaccine that blocks malaria transmission.

22 Apr 2013

NCI investigators design genetically engineered mouse to study human lung squamous cell carcinoma

National Cancer Institute (NCI) investigators have designed a genetically engineered mouse for use in the study of human lung squamous cell carcinoma (SCC). SCC is a type of non-small cell lung carcinoma, one of the most common types of lung cancer, with a five-year survival rate of about 15 percent.

18 Apr 2013

CRISPR helps some bacteria evade mammalian immune system

CRISPR, a system of genes that bacteria use to defend themselves against viruses, has been found to be involved in helping some bacteria evade the mammalian immune system.

18 Apr 2013

UTMB researchers identify protein that can interfere with the brain's response to leptin

Ever since the appetite-regulation hormone called leptin was discovered in 1994, scientists have sought to understand the mechanisms that control its action. It was known that leptin was made by fat cells, reduced appetite and interacted with insulin , but the precise molecular details of its function -details that might enable the creation of a new treatment for obesity - remained elusive.

18 Apr 2013

Research findings in mice may pave way towards understanding autism in human patients

For the first time, researchers have linked autism in a mouse model of the disease with abnormalities in specific regions of the animals' chromosomes.

17 Apr 2013

Supreme Court to decide crucial case on patenting human genes

The high court will hear a challenge to Myriad Genetics' patent of breast and ovarian cancer genes in a case that will affect the future of biomedical research, the fight against diseases like breast and ovarian cancer and a multi-billion dollar biotechnology business.

16 Apr 2013

Researchers use miniature electronic device to tap into internal reward system of mice

Using a miniature electronic device implanted in the brain, scientists have tapped into the internal reward system of mice, prodding neurons to release dopamine, a chemical associated with pleasure.

15 Apr 2013

Genetic Engineering News and Research

Understanding the role of dsRNA in antiviral host defense systems

Researchers use new analysis method to determine genes that result in cell death

Study: Breastfeeding can prevent the development of ADHD later in childhood

Research findings may pave way to new treatment for Alzheimer's disease in humans

Noninvasive imaging tests may play bigger role in diabetes management

Study: Tomatoes and soy may be effective in preventing prostate cancer

Progenitor cells remain highly dynamic in the adult brain

Complex network of molecules controls formation and activity of neuronal connections

Scientists create animal models by altering specific genes associated with a given disease

Experts report new outbreaks and increased spread of Cassava Brown Streak Disease

Study: Combination of chemotherapy and nerve-protecting agents can prevent anemia

Novel screening method for identifying inhibitors of EZH2 methyltransferase

Violence and Gender: New refereed journal delves into gender basis of violence

Edible malarial vaccine may work against other viral and bacterial infections

NCI investigators design genetically engineered mouse to study human lung squamous cell carcinoma

CRISPR helps some bacteria evade mammalian immune system

UTMB researchers identify protein that can interfere with the brain's response to leptin

Research findings in mice may pave way towards understanding autism in human patients

Supreme Court to decide crucial case on patenting human genes

Researchers use miniature electronic device to tap into internal reward system of mice

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