Protein C News and Research

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Simple and accurate detection system can redefine medical diagnostics field

In biology and medicine, we often need to detect biological molecules. For example, in cancer diagnostics, doctors need quick and reliable ways of knowing if tumor cells are present in the patient's body.

25 Jul 2015

Changes in UCH-L1 and GFAP proteins linked to trauma-related brain damage

Researchers have shown that the levels of two proteins present in blood and cerebrospinal fluid increase significantly at different time points following traumatic brain injury (TBI), confirming their potential value as biomarkers of trauma-related brain damage.

25 Jul 2015

Prostate cancer patients more likely to receive medical care matched to level of risk

After decades of overtreatment for low-risk prostate cancer and inadequate management of its more aggressive forms, patients are now more likely to receive medical care matched to level of risk, according to a study by researchers at UC San Francisco.

25 Jul 2015

New findings unlock clues to disease protection

When disease-resistant rice is invaded by disease-causing bacteria, a small protein produced by the bacteria betrays the invader. Upon recognizing that protein, the rice plants sense that a microbial attack is underway and are able to mount an immune response to fend off bacterial infection, reports a research team led by the University of California, Davis.

25 Jul 2015

Vital molecular mechanism in plants has similarities to certain signaling mechanisms in humans

Scientists at Van Andel Research Institute have revealed an important molecular mechanism in plants that has significant similarities to certain signaling mechanisms in humans, which are closely linked to early embryonic development and to diseases such as cancer.

25 Jul 2015

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Researchers from CalciMedica, Inc. and the University of Liverpool today announced the publication of a paper describing positive effects of calcium release-activated calcium (CRAC) channel inhibitors in animal models of acute pancreatitis. The paper, titled "Inhibitors of ORAI1 prevent cytosolic calcium-associated injury of human pancreatic acinar cells and acute pancreatitis in 3 mouse models" appears in the August edition of the journal Gastroenterology.

25 Jul 2015

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

Pathogenic bacteria develop killer machines that work very specifically and highly efficiently. Scientists from the University of Freiburg have solved the molecular mechanism of a fish toxin that could be used in the future as a medication to treat cancer. The scientists have now published their research in the journal Nature Communications.

25 Jul 2015

First malaria vaccine a step closer

Mosquirix, the first malaria vaccine to be submitted for regulatory approval, has gained the support of the European Medicines Agency’s Committee for Medicinal Products for Human Use (CHMP).

24 Jul 2015

New computer algorithm helps scientists see drug's activity inside the body

Researchers at Columbia University Medical Center have developed a computer algorithm that is helping scientists see how drugs produce pharmacological effects inside the body. The study, published in the journal Cell, could help researchers create drugs that are more efficient and less prone to side effects, suggest ways to regulate a drug's activity, and identify novel therapeutic uses for new and existing compounds.

24 Jul 2015

New study reveals protein's critical role in development and progression of AML

A new study by researchers at University of California, San Diego School of Medicine reveals a protein's critical - and previously unknown -- role in the development and progression of acute myeloid leukemia (AML), a fast-growing and extremely difficult-to-treat blood cancer.

24 Jul 2015

Case Western cancer researchers develop algorithm to detect DNA copy-number alterations in tumors

An algorithm dubbed ENVE could be the Google for genetic aberrations — and it comes from Case Western Reserve.

24 Jul 2015

U of T researchers discover DNA ambulance

U of T researchers have discovered how severely damaged DNA is transported within a cell and how it is repaired.

24 Jul 2015

Breakthrough reveals influence of schizophrenia’s 'Rosetta Stone' gene in brain development

Scientists have identified a critical function of what they believe to be schizophrenia's "Rosetta Stone" gene that could hold the key to decoding the function of all genes involved in the disease.

24 Jul 2015

Researchers find way to reverse clotting factor deficiency that triggers hemophilia A

Sufferers of hemophilia live in a perpetual state of stress and anxiety: their joints wear down prematurely and they have bleeding episodes that feel like they will never end. Their bodies lack the ability to make the clotting factor responsible for the coagulation of blood so any cut or bruise can turn into an emergency without immediate treatment.

24 Jul 2015

Nutrition vital for patients recovering from severe burns

For someone recovering from severe burns, eating is often the last thing they want to do. However, burn specialists at The Ohio State University Wexner Medical Center say nutrition is so vital to their patients' recovery that they make it a quality indicator for patient care.

24 Jul 2015

New Histone Antibody Specificity Database allows scientists to find right antibodies for biomedical research

For years, a crisis has been brewing in molecular biology. The problem is that antibodies--research tools used to identify key proteins at work in a cell--aren't always what they seem. Unreliable antibodies have led to numerous instances of false findings, failed experiments, and wasted money and samples.

24 Jul 2015

Regular exercise, healthy diet may help reduce knee pain for overweight adults with diabetes

Knee pain in older adults, often caused by osteoarthritis, usually means more visits to the doctor and also can be a harbinger of disability.

24 Jul 2015

Gladstone Institutes announces new business endeavor with Evotec and Dolby Family Ventures

The Gladstone Institutes announces the creation of Cure Network Ventures Inc. and Cure Network Dolby Acceleration Partners, LLC, a business endeavor with Dolby Family Ventures and Evotec AG, which will focus on Alzheimer's disease. Working through Cure Network Ventures, Inc., the new company will help expedite the translation of relevant scientific discoveries from the Gladstone Institute of Neurological Disease into the development of potential therapies.

24 Jul 2015

Mayo Clinic researchers study HDAC inhibitors to find effective treatments for anaplastic thyroid cancer

In their bid to find the best combination of therapies to treat anaplastic thyroid cancer (ATC), researchers on Mayo Clinic's Florida campus demonstrated that all histone deacetylase (HDAC) inhibitors are not created equal.

24 Jul 2015

SutroVax completes $22 million Series A financing

SutroVax, a recently established biopharmaceutical vaccine company, today announced the completion of a $22 million Series A financing. SutroVax is developing vaccines for infectious disease targets, with an initial emphasis on best-in-class conjugate vaccines, using an exclusive license to Sutro Biopharma's Xpress CF and Xpress CF+ platforms for cell free protein synthesis and site-specific conjugation respectively.

23 Jul 2015

Protein C News and Research

Simple and accurate detection system can redefine medical diagnostics field

Changes in UCH-L1 and GFAP proteins linked to trauma-related brain damage

Prostate cancer patients more likely to receive medical care matched to level of risk

New findings unlock clues to disease protection

Vital molecular mechanism in plants has similarities to certain signaling mechanisms in humans

New paper describes positive effects of CRAC channel inhibitors in animal models of acute pancreatitis

Researchers decode molecular mechanism of fish toxin that has potential to treat cancer

First malaria vaccine a step closer

New computer algorithm helps scientists see drug's activity inside the body

New study reveals protein's critical role in development and progression of AML

Case Western cancer researchers develop algorithm to detect DNA copy-number alterations in tumors

U of T researchers discover DNA ambulance

Breakthrough reveals influence of schizophrenia’s 'Rosetta Stone' gene in brain development

Researchers find way to reverse clotting factor deficiency that triggers hemophilia A

Nutrition vital for patients recovering from severe burns

New Histone Antibody Specificity Database allows scientists to find right antibodies for biomedical research

Regular exercise, healthy diet may help reduce knee pain for overweight adults with diabetes

Gladstone Institutes announces new business endeavor with Evotec and Dolby Family Ventures

Mayo Clinic researchers study HDAC inhibitors to find effective treatments for anaplastic thyroid cancer

SutroVax completes $22 million Series A financing

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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