Genetic Engineering News and Research

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RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

A new hypothesis has been developed by researchers in Bochum on how Alzheimer's disease could occur. They analysed the interaction of the proteins FE65 and BLM that regulate cell division.

15 Apr 2013

Engineered protein from flesh-eating bacteria acts as molecular 'superglue'

In a classic case of turning an enemy into a friend, scientists have engineered a protein from flesh-eating bacteria to act as a molecular "superglue" that promises to become a disease fighter. And their latest results, which make the technology more versatile, were the topic of a report here today at the 245th National Meeting & Exposition of the American Chemical Society, the world's largest scientific society.

12 Apr 2013

Modulation of cerebral endocannabinoid system may help treat Fragile X chromosome syndrome

Researchers at the University of the Basque Country (UPV/EHU) and the Achucarro neurosciences centre have discovered a new therapy for the fragile X chromosome syndrome. This new therapy proposes the modulation of the cerebral endocannabinoid system in order to ameliorate the symptoms of the disease.

11 Apr 2013

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Scientists at The Scripps Research Institute have shed light on one of the major toxic mechanisms of Alzheimer's disease. The discoveries could lead to a much better understanding of the Alzheimer's process and how to prevent it.

11 Apr 2013

Researchers evaluate Pexa-Vec to slow progression of liver cancer

As part of a multicenter clinical trial, researchers at University of California, San Diego School of Medicine are evaluating Pexa-Vec (JX-594) to slow the progression of hepatocellular carcinoma or liver cancer. Pexa-Vec is a genetically engineered virus that is used in the smallpox vaccine.

10 Apr 2013

New immunotherapies are seldom developed for childhood cancer

More often than not, cancer immunotherapies that work in adults are used in modified ways in children. Seldom are new therapies developed just for children, primarily because of the small number of pediatric patients relative to the adult cancer patient population.

9 Apr 2013

Study: Chicken-killing virus is a promising treatment for prostate cancer

A study at the Virginia-Maryland Regional College of Veterinary Medicine has identified a chicken-killing virus as a promising treatment for prostate cancer in humans.

9 Apr 2013

Scientists succeed to control cells' behavior using light

Scientists at Washington University School of Medicine in St. Louis have shown they can coax cells to move toward a beam of light. The feat is a first step toward manipulating cells to control insulin secretion or heart rate using light.

9 Apr 2013

Johns Hopkins researchers find how gout-linked genetic mutation contributes to disease

Johns Hopkins scientists have found out how a gout-linked genetic mutation contributes to the disease: by causing a breakdown in a cellular pump that clears an acidic waste product from the bloodstream.

9 Apr 2013

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

A physician-researcher from The Children's Hospital of Philadelphia will lead the first-ever pediatric "Dream Team" solely focused on creating new treatments for the most challenging childhood cancers.

8 Apr 2013

Penn Medicine scientist, trial participant detail experiences on leading edge of gene therapy

Harnessing the patient's own immune system to fight cancer through genetic modification of their own cells is rapidly emerging as a promising treatment option.

6 Apr 2013

China begins slaughter of birds in Shanghai market after 6th death from H7N9 announced; U.S., global experts begin vaccine research

"China announced a sixth death from a new bird flu strain Friday, while authorities in Shanghai halted the sale of live fowl and slaughtered all poultry at a market where the virus was detected in pigeons being sold for meat," the Associated Press reports (Wong, 4/5).

6 Apr 2013

Study: Robotic companions can reduce feelings of pain, emotional anxiety among pediatric patients

Pet therapy can help patients cope with the pain, stress, and emotional effects of a serious illness, but access to a companion animal is not always possible. Robotic animals may offer the same benefits, as explored in a fascinating study presented in Cyberpsychology, Behavior, and Social Networking, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers.

5 Apr 2013

Dermatology researcher secures federal grant to explore psoriasis

A dermatology researcher at Case Western Reserve University School of Medicine has secured a five-year, $1.9 million federal grant to explore whether a specific molecule may play a pivotal role in the development and progression of psoriasis.

5 Apr 2013

UC San Francisco researchers outline cell-based therapeutics as a "third pillar” of medicine

Treating patients with cells may one day become as common as it is now to treat the sick with drugs made from engineered proteins, antibodies or smaller chemicals, according to UC San Francisco researchers.

4 Apr 2013

Study: Altering brain activity with laser light eliminates addictive behavior in rats

By stimulating one part of the brain with laser light, researchers at the National Institutes of Health (NIH) and the Ernest Gallo Clinic and Research Center at UC San Francisco (UCSF) have shown that they can wipe away addictive behavior in rats - or conversely turn non-addicted rats into compulsive cocaine seekers.

4 Apr 2013

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Many recent studies have suggested that obesity is associated with chronic inflammation in fat tissues. Researchers at Sanford-Burnham Medical Research Institute have discovered that an imbalance between an enzyme called neutrophil elastase and its inhibitor causes inflammation, obesity, insulin resistance, and fatty liver disease.

3 Apr 2013

Explosive growth in tissue engineering and regenerative medicine leads to innovative, promising applications

Explosive growth in the field of tissue engineering and regenerative medicine has led to innovative and promising applications and techniques, many of which are now being tested in human clinical trials.

30 Mar 2013

Research findings could lead to improved treatment for neuropathic pain

An international team of scientists, led by researchers at the University of California, San Diego School of Medicine, says a key protein in Schwann cells performs a critical, perhaps overarching, role in regulating the recovery of peripheral nerves after injury.

28 Mar 2013

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

The Bellvitge Biomedical Research Institute has signed a licensing agreement with the Spanish biotech company Histocell to make use of a patent for the treatment of acute pulmonary diseases with mesenchymal stem cells.

28 Mar 2013

Genetic Engineering News and Research

RUB researchers develop new hypothesis on occurrence of Alzheimer's disease

Engineered protein from flesh-eating bacteria acts as molecular 'superglue'

Modulation of cerebral endocannabinoid system may help treat Fragile X chromosome syndrome

TSRI scientists shed light on major toxic mechanisms of Alzheimer's disease

Researchers evaluate Pexa-Vec to slow progression of liver cancer

New immunotherapies are seldom developed for childhood cancer

Study: Chicken-killing virus is a promising treatment for prostate cancer

Scientists succeed to control cells' behavior using light

Johns Hopkins researchers find how gout-linked genetic mutation contributes to disease

Physician-researcher to lead pediatric Dream Team to create new treatments for childhood cancers

Penn Medicine scientist, trial participant detail experiences on leading edge of gene therapy

China begins slaughter of birds in Shanghai market after 6th death from H7N9 announced; U.S., global experts begin vaccine research

Study: Robotic companions can reduce feelings of pain, emotional anxiety among pediatric patients

Dermatology researcher secures federal grant to explore psoriasis

UC San Francisco researchers outline cell-based therapeutics as a "third pillar” of medicine

Study: Altering brain activity with laser light eliminates addictive behavior in rats

Imbalance between neutrophil elastase and α1-antitrypsin leads to obesity, inflammation

Explosive growth in tissue engineering and regenerative medicine leads to innovative, promising applications

Research findings could lead to improved treatment for neuropathic pain

IDIBELL signs agreement with Histocell to use patent for acute pulmonary diseases with stem cells

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