Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

HMC signal could be used to detect diseases and to personalize medication

Common diseases like allergy, diabetes and other immune diseases have increased dramatically in recent decades. This indicates that the environment may have a more important role than genes in explaining this increase.

24 Jun 2016

NCX1 protein could help prevent progression of heart failure

A protein known to be crucial for maintaining the balance of calcium in cells could prove useful in halting the progression of heart failure.

24 Jun 2016

Mutant fruit flies provide insight into origins of Parkinson's disease

The neurodegeneration that occurs in Parkinson’s disease is a result of stress on the endoplasmic reticulum in the cell rather than failure of the mitochondria as previously thought, according to a study in fruit flies.

24 Jun 2016

Researchers identify new potential target for pancreatic cancer treatment

Using an innovative approach to identify a cancer's genetic vulnerabilities by more swiftly analyzing human tumors transplanted into mice, researchers have identified a new potential target for pancreatic cancer treatment, published online in Cell Reports.

24 Jun 2016

New insights into cancer cell signaling could help prevent metastases

Research published yesterday in Nature Communications has revealed a previously unknown mechanism by which metastasising cancer cells survive when they break away from the primary tumour. It is hoped that the discovery could help with the development of novel cancer treatments that prevent metastasis.

24 Jun 2016

Researchers reveal integrins could be key to survival mechanism in cancer cells

Cancer cells appear to depend on an unusual survival mechanism to spread around the body, according to an early study led by Queen Mary University of London. The discovery could help with future development of novel treatments to prevent metastasis and secondary tumours.

24 Jun 2016

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Scientists from the Institut Pasteur and the CNRS, in collaboration with Imperial College London and the University of Vienna, Austria, have identified antibodies that can efficiently neutralize both the dengue virus and the Zika virus.

24 Jun 2016

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Potent doses of broccoli sprout extract activate a "detoxification" gene and may help prevent cancer recurrence in survivors of head and neck cancer, according to a trial by the University of Pittsburgh Cancer Institute, partner with UPMC CancerCenter, confirming preliminary results presented last year at the American Association for Cancer Research Annual Meeting.

24 Jun 2016

Yale-led study shows how EGFR silences tumor suppressor genes

A Yale-led study describes how a known cancer gene, EGFR, silences genes that typically suppress tumors. The finding, published in Cell Reports, may lead to the development of more effective, individualized treatment for patients with lung cancer and other cancer types.

24 Jun 2016

Scientists discover how faulty genetic instructions contribute to development of AML

Scientists have previously identified a series of genetic errors that commonly occur inside cancerous blood cells, but it hasn't been clear exactly how those genetic malfunctions create immature blood cells that overpopulate, crowd out healthy cells and spread in patients with acute myeloid leukemia or AML.

24 Jun 2016

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

Alzheimer's disease is the leading cause of dementia in the elderly and occurs in all ethnic and racial groups. It affects more than 5 million people age 65 and older in the United States alone and there is currently no effective treatment or cure.

24 Jun 2016

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

The first global mapping of artemisinin resistance has definitively confirmed that resistance to the main drug currently used in the treatment of Plasmodium falciparum malaria is for the moment confined to Southeast Asia and has not spread to sub-Saharan Africa.

24 Jun 2016

Scientists provide new insights into role of star-shaped brain cells in memory, learning

A molecule that enables strong communication between our brain and muscles appears to also aid essential communication between our neurons, scientists report.

23 Jun 2016

New optical detection technology could be effective to monitor blood-glucose levels

A newly developed method for detecting glucose based on how it absorbs a specific type of light could spell the end of the painful, invasive finger-prick tests diabetics rely on to monitor their condition, says a Texas A&M University biomedical engineer who is developing the technology.

23 Jun 2016

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

A team led by researchers at St. Jude Children's Research Hospital report that mice lacking the protein Alix develop hydrocephalus or "water on the brain." Alix ensures that epithelial cells of the choroid plexus are oriented correctly with respect to one another to prevent compromise of the epithelial barrier.

23 Jun 2016

New optogenetic manipulation technique could possibly reduce migraine headaches

Despite decades of research, migraines are often not well controlled with medication. For those prone to this type of debilitating headache, it sometimes seems nothing can stop the pain and the sensitivity to light. But what if light itself was key to their relief?

23 Jun 2016

Researchers uncover new clues about role of glucosamine in early embryonic development

Most pregnant women with well-controlled diabetes give birth to healthy children. But their babies run much higher risks of birth defects than babies born to women without diabetes, because very early in embryonic development, the babies are exposed to higher levels of glucose in maternal blood.

23 Jun 2016

Sperm of smokers has greater extent of DNA damage than that of non-smokers

A recent study found that that sperm of men who smoke has a greater extent of DNA damage than that of non-smokers.

22 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

One of the alterations that most affects the quality of life of the elderly is muscle wastage and the resulting loss of strength, a condition known as sarcopenia. At about 55 years old, people begin to lose muscle mass, this loss continues into old age, at which point it becomes critical.

22 Jun 2016

Protein News and Research

Further Reading

HMC signal could be used to detect diseases and to personalize medication

NCX1 protein could help prevent progression of heart failure

Mutant fruit flies provide insight into origins of Parkinson's disease

Researchers identify new potential target for pancreatic cancer treatment

New insights into cancer cell signaling could help prevent metastases

Researchers reveal integrins could be key to survival mechanism in cancer cells

Scientists isolate antibodies capable of neutralizing dengue and Zika virus

Broccoli sprout extract may help prevent cancer recurrence in head and neck cancer survivors

Yale-led study shows how EGFR silences tumor suppressor genes

Scientists discover how faulty genetic instructions contribute to development of AML

University of Miami researchers awarded new contracts to detect genetic factors linked to Alzheimer's disease risk

KARMA study confirms resistance to anti-malarial drugs confined to Southeast Asia

Scientists provide new insights into role of star-shaped brain cells in memory, learning

New optical detection technology could be effective to monitor blood-glucose levels

Lack of Alix protein leads to occurrence of hydrocephalus in the brain

New optogenetic manipulation technique could possibly reduce migraine headaches

Researchers uncover new clues about role of glucosamine in early embryonic development

Sperm of smokers has greater extent of DNA damage than that of non-smokers

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Mitofusin 2 protein could serve as therapeutic target to ameliorate sarcopenia in older adults

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