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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

MicroRNA plays role in blocking development of arterial thrombosis

The dangers of arterial thrombosis - the formation of blood clots that can block arteries and cause illness or death - can escalate through a vicious cycle of coagulation and inflammation.

15 Jun 2016

Immunotherapy drugs given after chemotherapy may benefit ovarian cancer patients

Women with advanced ovarian cancer may benefit more from immunotherapy drug treatments if they are given straight after chemotherapy, according to a new study published in Clinical Cancer Research today.

15 Jun 2016

Researchers find new method to replicate one of earliest changes in Alzheimer’s disease

Researchers at the Babraham Institute have found a way to replicate one of the earliest changes in Alzheimer's disease in a dish. This means that it should now be possible to find out a lot more about why it happens - and how to stop it. The new findings are published in the journal Molecular Neurodegeneration and supported by the charity Alzheimer's Research UK.

15 Jun 2016

Researchers find unexpected connection between two types of calming immune cells

Biologically speaking, we carry the outside world within us. The food we ingest each day and the trillions of microbes that inhabit our guts pose a constant risk of infection--and all that separates us from these foreign entities is a delicate boundary made of a single layer of cells.

15 Jun 2016

Excessive AhR signaling helps explain dioxin-induced abnormal behavioral alterations in mice

Dioxins are environmental pollutants that stay in the body for long periods of time because they can accumulate in fat tissue. They are mainly by-products of combustion and industrial processes.

15 Jun 2016

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

PharmaMar today announced the start of a multicenter, prospective, pivotal study to analyze the efficacy of the antitumoral compound of marine origin, plitidepsin in patients with relapsed and refractory angioimmunoblastic T-cell lymphoma.

15 Jun 2016

Four miRNAs may hold vital clue to disease progression in gliobastoma

Scientists at the Helmholtz Zentrum München and the Ludwig Maximilians University of Munich have developed a new method of predicting disease progression in gliobastoma patients who have undergone standard treatment.

14 Jun 2016

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Non-small cell lung cancers have a collective reputation for not responding very well to chemotherapy. Researchers at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging (SNMMI) are presenting a means of evaluating an immunotherapy that fights off NSCLC by strengthening a patient's own immune system.

14 Jun 2016

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

Examining databases of proteins' 3-D shapes, scientists at Washington University School of Medicine in St. Louis have identified more than 850 DNA mutations that appear to be linked to cancer.

14 Jun 2016

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

A team of researchers at the University of South Florida investigating the short and long-term effects of ischemic stroke in a rodent model has found that stroke can cause long-term damage to the blood-spinal cord barrier (BSCB), creating a "toxic environment" in the spinal cord that might leave stroke survivors susceptible to motor dysfunction and disease pathology.

14 Jun 2016

Study provides more insight into treatment options for severe hemophilia A

Families of children with severe hemophilia A may want to take a fresh look at treatment options from human plasma. A study published in the New England Journal of Medicine on May 26 showed that participants who received a recombinant therapy— the present standard in the United States — developed antibodies or "inhibitors" to the treatments at almost twice the rate as those whose treatments were made from human plasma.

14 Jun 2016

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

Cisplatin is a common, powerful chemotherapy agent used for a wide range of cancers such as breast, ovarian and lung, that in a handful of days can also permanently damage or destroy patients' kidneys.

14 Jun 2016

New experimental antibiotic can help combat MRSA infections

A new experimental antibiotic developed by a team of scientists at Rutgers University successfully treats the deadly MRSA infection and restores the efficacy of a commonly prescribed antibiotic that has become ineffective against MRSA.

14 Jun 2016

New receptor discovery could lead to novel mosquito repellents

Major rainfall across most of Texas triggering hordes of mosquitos coupled with seemingly constant mosquito-related Zika virus media reports from around the globe may have set the stage perfectly for what one researcher deems as a very significant discovery in man's war against earth's leading human disease carrier.

14 Jun 2016

Researchers unravel species-function relationships in gut microbial genomes

Despite recent progress, the organization and ecological properties of the intestinal microbial ecosystem remain under investigated. Using a manually curated metabolic module framework for (meta-)genomic data analysis, Sara Vieira-Silva, Gwen Falony and colleagues from the Jeroen Raes lab studied species-function relationships in gut microbial genomes and microbiomes.

14 Jun 2016

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Alzheimer's is a devastating and incurable disease marked by beta-amyloid and tau protein aggregations in the brain, yet the direct relationship between these proteins and neurodegeneration has remained a mystery.

14 Jun 2016

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

A new study suggests that blocking an enzyme called PRMT5 in tumor cells could be a promising new strategy for the treatment of glioblastoma (GB), the most aggressive and lethal form of brain cancer.

14 Jun 2016

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

A study in the Journal of the American Society of Nephrology suggests a new therapeutic approach to treat the development of chronic kidney disease secondary to chronic heart failure, known as cardiorenal syndrome type 2.

14 Jun 2016

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Malignant neuroendocrine tumors (NETs) are relatively rare, notoriously difficult to treat, and associated with poor long-term survival. According to research presented at the 2016 Annual Meeting of the Society of Nuclear Medicine and Molecular Imaging, an investigative blood test could predict how patients will respond to peptide receptor radionuclide therapy (PRRT) before they commit to a course of treatment.

14 Jun 2016

Scientists develop new tool to overcome major hurdle for personalized medicine

Scientists from EPFL and ETHZ have developed a powerful tool for exploring and determining the inherent biological differences between individuals, which overcomes a major hurdle for personalized medicine.

13 Jun 2016

Protein News and Research

Further Reading

MicroRNA plays role in blocking development of arterial thrombosis

Immunotherapy drugs given after chemotherapy may benefit ovarian cancer patients

Researchers find new method to replicate one of earliest changes in Alzheimer’s disease

Researchers find unexpected connection between two types of calming immune cells

Excessive AhR signaling helps explain dioxin-induced abnormal behavioral alterations in mice

PharmaMar announces initiation of pivotal plitidepsin clinical trial in patients with T-cell lymphomas

Four miRNAs may hold vital clue to disease progression in gliobastoma

FDG-PET imaging tracks ability of atezolizumab to bolster immunity against NSCLC

Databases of proteins' 3-D shapes help identify more than 850 DNA mutations linked to cancer

Stroke can cause long-term damage to blood-spinal cord barrier, study finds

Study provides more insight into treatment options for severe hemophilia A

Researchers aim to protect kidneys while improving cisplatin's efficacy against cancer

New experimental antibiotic can help combat MRSA infections

New receptor discovery could lead to novel mosquito repellents

Researchers unravel species-function relationships in gut microbial genomes

New imaging study links tau proteins to neurodegenerative pathology of Alzheimer's disease

Study underscores importance of developing PRMT5 inhibitors as promising treatment for GB patients

GPCR-Gβγ inhibition therapy could prevent chronic and acute kidney damage in heart failure patients

Genetic blood test can help predict patient’s respone to neuroendocrine cancer therapy

Scientists develop new tool to overcome major hurdle for personalized medicine

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