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Study provides insights into non-oncogenic addictions of tumors

Researchers at Sanford Burnham Prebys Medical Discovery Institute (SBP) and UC San Diego have shown that tumors can ensure a more reliable nutrient supply by eliminating the p62 protein in surrounding stromal tissue.

9 Oct 2017

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Preeclampsia is the most dangerous form of hypertension during a pregnancy and can be fatal for both mother and child. Though it is known to originate in the placenta, the root causes remain largely a mystery.

6 Oct 2017

Study sheds light on complex process involved in development of sperm stem cells

New research from scientists at Huntsman Cancer Institute at the University of Utah and collaborators at University of Utah Health sheds light on the complex process that occurs in the development of human sperm stem cells.

5 Oct 2017

GW researcher awarded NIH grant to study how cocaine use affects HIV infection

Following studies showing that cocaine influences the replication and transcription of HIV, a researcher at the George Washington University School of Medicine and Health Sciences was awarded more than $2.3 million from the National Institutes of Health to look deeper into the involved molecular mechanisms that allow this effect to happen.

5 Oct 2017

MRI and ultrasound can detect fetal brain damage caused by Zika in utero

Clinicians managing Zika-affected pregnancies should use magnetic resonance imaging (MRI) in addition to standard ultrasound (US) because the more detailed MRI images can reveal more extensive areas of damage to the developing fetal brain, according to research presented during IDWeek 2017.

4 Oct 2017

TSRI scientists developed new strategy to discover novel anti-cancer therapies

Scientists at The Scripps Research Institute (TSRI) have developed and demonstrated a promising new strategy for the discovery of novel anti-cancer therapies.

30 Sep 2017

METTLER TOLEDO’s updated UV/VIS spectrophotometers can perform color measurements, automation

The updated UV/VIS Excellence spectrophotometers from METTLER TOLEDO can now measure spectra and color simultaneously, streamlining analyses.

28 Sep 2017

Chromatrap ChIP-Seq kits can deliver streamlined protocol from nanograms of starting material

Chromatrap has demonstrated that its unique solid state patented technology allows for ChIP-seq assays to be routinely performed from as little as 500 ng of chromatin.

From Chromatrap® - Porvair Sciences Ltd 28 Sep 2017

Drug combination produces synergistic effect against growth of triple-negative breast cancer

In the hunt for novel treatments against an aggressive form of breast cancer, researchers combined a new protein inhibitor with a chemotherapy drug to create a powerful combination that resulted in cancer cell death.

26 Sep 2017

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

Two drugs, already approved for safe use in people, may be able to improve therapy for chronic myeloid leukemia (CML), a blood cancer that affects myeloid cells, according to results from a University of Iowa study in mice.

26 Sep 2017

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

A major health problem in older people is age-associated osteoporosis -- the thinning of bone and the loss of bone density that increases the risk of fractures. Often this is accompanied by an increase in fat cells in the bone marrow.

22 Sep 2017

Genome-wide study reveals how transposons get prepared for jumping

The genome of a typical organism consists of many genes that are stringed like beads. This alignment has been surprisingly stable even over very long evolutionary periods. In addition to these genes, there are also many mobile elements, referred to as parasitic, that are spread across the whole genome and aggregated into different families according to their relatedness.

22 Sep 2017

EPFL scientists discover metabolic differences between hepatoblastoma subtypes

Hepatoblastoma is a rare pediatric liver cancer, usually diagnosed in the first three years of life. Histological methods are used to distinguish between the different subtypes of hepatoblastoma.

18 Sep 2017

Steroid hormones could provide new insight into age-related bone loss

A group of steroid hormones could provide new insight into the bone loss and deterioration that occurs with aging, researchers at the Medical College of Georgia at Augusta University report.

15 Sep 2017

Research provides insight into how imbalance in neural precursor cells may contribute to brain diseases

Salk Institute scientists have discovered that an interaction between two key proteins helps regulate and maintain the cells that produce neurons.

15 Sep 2017

Heidelberg researchers gain new insights into formation of blood vessels

New insights into the development of the vascular system: researchers in the team of Dr Carmen Ruiz de Almodóvar of the Heidelberg University Biochemistry Center have discovered a crucial biological step that regulates the formation of blood vessels.

15 Sep 2017

Boise State professor wins federal grant to explore basic functions of the genome

It's rare for a faculty member in any physics department to earn a federal grant administered by the National Institutes of Health, but that is exactly what Boise State assistant professor and biophysicist Matt Ferguson has done.

14 Sep 2017

Disrupting DNA loops could be potential strategy to reduce tumor proliferation

The discovery of a mechanism by which normal brain cells regulate the expression of the NFIA gene, which is important for both normal brain development and brain tumor growth, might one day help improve therapies to treat brain tumors. The study appears in the journal Nature Neuroscience.

13 Sep 2017

Research uncovers new target for therapy, diagnosis, and prognosis of colon cancer

Genetic research conducted at LSU Health New Orleans School of Medicine and Stanley S. Scott Cancer Center demonstrated for the first time that a novel protein can cause normal cells in the lining of the colon to become malignant, grow and spread, as well as take on the characteristics of stem cells.

12 Sep 2017

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Scientists at The Scripps Research Institute have found a new approach to the "reprogramming" of ordinary adult cells into stem cells.

12 Sep 2017

Transcription News and Research

Study provides insights into non-oncogenic addictions of tumors

Change in epigenetic gene regulation by imprinting can trigger preeclampsia, study shows

Study sheds light on complex process involved in development of sperm stem cells

GW researcher awarded NIH grant to study how cocaine use affects HIV infection

MRI and ultrasound can detect fetal brain damage caused by Zika in utero

TSRI scientists developed new strategy to discover novel anti-cancer therapies

METTLER TOLEDO’s updated UV/VIS spectrophotometers can perform color measurements, automation

Chromatrap ChIP-Seq kits can deliver streamlined protocol from nanograms of starting material

Drug combination produces synergistic effect against growth of triple-negative breast cancer

Existing drugs may be able to improve therapy for chronic myeloid leukemia, mice study shows

UAB researchers detail underlying mechanism leading to age-associated osteoporosis

Genome-wide study reveals how transposons get prepared for jumping

EPFL scientists discover metabolic differences between hepatoblastoma subtypes

Steroid hormones could provide new insight into age-related bone loss

Research provides insight into how imbalance in neural precursor cells may contribute to brain diseases

Heidelberg researchers gain new insights into formation of blood vessels

Boise State professor wins federal grant to explore basic functions of the genome

Disrupting DNA loops could be potential strategy to reduce tumor proliferation

Research uncovers new target for therapy, diagnosis, and prognosis of colon cancer

TSRI scientists find new approach to reprogram ordinary adult cells into IPSCs

Discover how SciY empowers scientists

Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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