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Evidence suggests two patterns of early symptoms precede and predict later BD risk

Two patterns of antecedent or "prodromal" psychiatric symptoms may help to identify young persons at increased risk of developing bipolar disorder (BD), according to a new analysis in the Harvard Review of Psychiatry.

12 Jan 2018

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy.

12 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

Worsening of anxiety symptoms may be early indicator of Alzheimer's disease

A new study suggests an association between elevated amyloid beta levels and the worsening of anxiety symptoms. The findings support the hypothesis that neuropsychiatric symptoms could represent the early manifestation of Alzheimer's disease in older adults.

12 Jan 2018

New drug candidates may offer breakthrough in treatment of COPD

The study was a cooperative effort between the team headed by assistant professor Dr Jürgen Knobloch from the Medical Clinic III for Pneumology, Sleep and Respiratory Medicine at the Bergmannsheil University Hospital in Bochum, Germany, and Prof Dr Andrea Koch, member of the German Center for Lung Research, previously in Bochum, now at the Medical Clinic V for Pneumology at the LMU University Hospital in Munich, as well as a team from the company RespiVert Ltd, a subsidiary of Janssen Biotech Inc., and Prof Dr Erich Stoelben from the Lung Clinic in Köln-Merheim.

12 Jan 2018

Progression and regression rates of cervical lesions depend on patient's race, study shows

Physicians determining treatment options following abnormal Pap smears now have another factor to consider: the patient's race.

12 Jan 2018

Novel polygenic hazard score captures age variations of aggressive prostate cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually.

12 Jan 2018

Emergency department program reduces unnecessary admission of older patients by 33%

Roughly one third of all older patients age 65 and older visiting emergency departments nationwide are admitted to the hospital.

12 Jan 2018

Research provides insights into mechanisms governing healthy longevity

Keio University Global Research Institute, Tokyo publishes the January 2018 issue of KGRI Research Frontiers that includes researcher video profiles of Keio University researchers and research highlights from high impact publications including 'Regenerative medicine needs collaboration in and out of science in order to face current and future challenges; ‘Does eating fish protect you from depression?’; ‘Insights into the molecular mechanisms leading to kidney dysfunction in diabetic patients’; and ‘Ageing to 100 and beyond: Insights from demographic, phenotypic and genetic studies.

12 Jan 2018

New analysis highlights need for protective therapy to reduce risk of repeat heart attacks

AstraZeneca announced today the publication of a new analysis from an ongoing real-world quality registry that suggests the risk of experiencing a repeat heart attack (also known as a myocardial infarction or MI) from occlusions in non-stented arteries is twice as high as the risk stemming from the initially stented artery following a first heart attack.

12 Jan 2018

Dire view from within accident and emergency wards of England and Wales

The heads of accident and emergency (A&E) departments of hospitals all across England and Wales have warned Theresa May that more people are dying prematurely in the corridors of the A&E departments than before.

11 Jan 2018

SHEA releases new guidance on contact precautions for drug-resistant infections

New expert guidance released today by the Society for Healthcare Epidemiology of America advises hospitals on determining when they can safely discontinue contact precautions for patients with multi-drug resistant bacteria.

11 Jan 2018

Novel antifungal shows promise to stave off drug-resistant superbugs

Microscopic yeast have been wreaking havoc in hospitals around the world- creeping into catheters, ventilator tubes, and IV lines- and causing deadly invasive infection.

11 Jan 2018

Availability of qualified nurses in hospitals affects patient satisfaction

Satisfaction with care in hospitals declines when patients believe there are not enough nurses on wards, according to a new study based on the NHS Inpatient Survey published in the BMJ Open.

11 Jan 2018

Mount Sinai study uncovers potential link between Crohn's and Parkinson's in Jewish population

Mount Sinai Researchers have just discovered that patients in the Ashkenazi Jewish population with Crohn's disease (a chronic inflammatory of the digestive system) are more likely to carry the LRRK2 gene mutation.

11 Jan 2018

UPM researchers successfully simulate real-time migraine prediction system

UPM researchers, in collaboration with UCM and Hospital Universitario de la Princesa, have successfully simulated a system that alert patients to an incoming migraine crisis in real time. According to the simulation results, the reliability of this system is over 75%.

11 Jan 2018

Computer model based on AI improves analysis of kidney biopsies

The ability to quantify the extent of kidney damage and predict the life remaining in the kidney, using an image obtained at the time when a patient visits the hospital for a kidney biopsy, now is possible using a computer model based on artificial intelligence.

11 Jan 2018

CAP releases new guideline for HPV testing in patients with head and neck cancers

Certain head and neck cancers that are positive for high-risk types of human papillomavirus (HPV) have a better prognosis and may need less aggressive treatment.

11 Jan 2018

New TSRI study uncovers workings of first potential treatment for Marburg virus

With a mortality rate of up to 88 percent, Marburg virus can rip through a community in days. In 2005, an outbreak of Marburg virus struck a pediatric ward in the country of Angola. With no treatment available, doctors struggled to help as the virus killed 329 of 374 infected patients.

11 Jan 2018

New HSS study may signal hope for patients suffering from scleroderma

Scleroderma is a terribly debilitating disease with no effective treatments and the mortality rates are still upwards of 20%-50%, the highest of any rheumatic disease.

11 Jan 2018