Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Timing of evening meals not linked to childhood obesity

Researchers at King's College London have found no significant link between eating the evening meal after 8pm and excess weight in children, according to a paper published this month in the British Journal of Nutrition.

17 May 2016

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

The motor protein Myo1c binds to Neph1, a protein crucial for ensuring effective filtration by the kidney, and serves as one mode of its cellular transport, according to findings by investigators at the Medical University of South Carolina and their collaborators reported in the May 16, 2016 issue of Molecular and Cellular Biology.

17 May 2016

Scientists uncover whole new way of treating antibiotic-resistant superbugs

Australian scientists may have found a way to stop deadly bacteria from infecting patients. The discovery could lead to a whole new way of treating antibiotic-resistant "superbugs". The researchers have uncovered what may be an Achilles heel on the bacteria cell membrane that could act as a potential novel drug target.

17 May 2016

McGill researchers discover role of folliculin protein in regulating activity of fat cells

Researchers have uncovered a new molecular pathway for stimulating the body to burn fat - a discovery that could help fight obesity, diabetes and cardiovascular disease.

17 May 2016

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

AbbVie, a global biopharmaceutical company, today announced The Lancet Oncology published results from the Phase 2, single arm, open label trial studying venetoclax in patients with relapsed/refractory (R/R) chronic lymphocytic leukaemia (CLL) with 17p deletion.

17 May 2016

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Researchers at Beth Israel Deaconess Medical Center have identified an enzyme that is significantly elevated in mouse models of systemic lupus erythematosus and in blood samples of patients with lupus.

17 May 2016

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

Ipsen S.A., a global specialty-driven pharmaceutical company, and the Institute of Molecular and Cell Biology (IMCB), a research institute under the aegis of the Agency for Science, Technology and Research (A*STAR), Singapore, today announced the signature of a research partnership to study the intracellular trafficking of botulinum neurotoxins (BoNTs) within neurons.

16 May 2016

DeNovix honored at Scientists’ Choice Awards® Best New Life Sciences Product 2015

DeNovix’s DS-11 FX+ Series of Spectrophotometers / Fluorometers was awarded runner-up position in the annual Scientists Choice Awards® Best New Life Sciences Product 2015. The award was presented during this year’s American Association for Cancer Research (AACR) annual meeting.

16 May 2016

Unlocking the dark proteome: an interview with Dr Kriwacki

The term dark proteome refers to proteins whose structural features and thus functions are not well understood. Many proteins within the dark proteome do not fold into stable three-dimensional structures. These proteins are called intrinsically disordered proteins (IDPs) and feature highly flexible, disordered confirmations.

16 May 2016

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

In a pair of related studies, chemists from the Florida campus of The Scripps Research Institute (TSRI) have identified and designed dozens of molecular “warheads” that not only can detect a key biomarker of cancer, but also could be developed into a potent new class of drug candidates for a range of diseases.

13 May 2016

Researchers identify out of control immune system linked to neurodegenerative diseases

AN out of control immune system has been identified as a possible cause of neurodegenerative diseases such as Alzheimer’s.

13 May 2016

CTD helps scientists explore impact of environmental exposures on human health

Two new studies from a group at North Carolina State University give researchers new strategies for connecting environmental exposures to human health effects.

13 May 2016

General anesthesia affects heart muscle proteins and causes depressed heart function, study shows

Anesthesia is used every day, but surprisingly little is known about one of its most dangerous side effects--depressed heart function.

13 May 2016

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Researchers from the University of Chicago have shown that inhibiting autophagy, a self-devouring process used by cells to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models.

13 May 2016

Genetic change to non-DNA structures in cell can cause cancer

A mutation that affects the proteins that package DNA--without changing the DNA itself--can cause a rare form of cancer, according to new findings in this week's Science from researchers at The Rockefeller University.

13 May 2016

New way of understanding neurodegeneration may lead to novel treatments

University of Adelaide researchers have developed a new theory for the causes of dementia and other neurodegenerative diseases, involving an out-of-control immune system.

13 May 2016

Researchers investigate effects of non-allergenic components of pollen on allergy sufferers

Up to now, research into pollen allergies has largely focused on allergens - those components of pollen that trigger hypersensitivity reactions. When it comes into contact with the nasal mucous membrane, however, pollen releases a host of other substances in addition to allergens.

13 May 2016

Histone mutation linked to fatal pediatric brain tumor

A single defect in a gene that codes for a histone — a "spool" that wraps idle DNA — is linked to pediatric cancers in a study published today in the journal Science.

13 May 2016

Specific gene links impulsive behavior to binge drinking in teens

From minor acts of rebellion such as bunking off school, to the more serious experimentation with illicit substances, the teenage years can be a stressful time for parents.

12 May 2016

Scientists clarify molecular mechanism of Visomitin drug

An international team of scientists led by researchers from the Lomonosov Moscow State University succeeded to clarify the molecular mechanism of a drug created in Russia and designed to prevent the damaging of cell mitochondria by reactive oxygen species. This work is published in the journal Oxidative Medicine and Cellular Longevity.

12 May 2016

Protein News and Research

Further Reading

Timing of evening meals not linked to childhood obesity

Motor protein Myo1c uses actin cytoskeleton as 'track' for Neph1 transport

Scientists uncover whole new way of treating antibiotic-resistant superbugs

McGill researchers discover role of folliculin protein in regulating activity of fat cells

Phase 2 results of AbbVie’s venetoclax in patients with R/R CLL with 17p deletion published in The Lancet Oncology

Study shows inhibition of SHP-2 enzyme can diminish lupus symptoms

Ipsen partners with IMCB to advance understanding and research of Botulinum Neurotoxin Biology

DeNovix honored at Scientists’ Choice Awards® Best New Life Sciences Product 2015

Unlocking the dark proteome: an interview with Dr Kriwacki

TSRI chemists identify and design potent therapeutic ‘warheads’ for different diseases

Researchers identify out of control immune system linked to neurodegenerative diseases

CTD helps scientists explore impact of environmental exposures on human health

General anesthesia affects heart muscle proteins and causes depressed heart function, study shows

Inhibiting autophagy can effectively block tumor cell migration, breast cancer metastasis

Genetic change to non-DNA structures in cell can cause cancer

New way of understanding neurodegeneration may lead to novel treatments

Researchers investigate effects of non-allergenic components of pollen on allergy sufferers

Histone mutation linked to fatal pediatric brain tumor

Specific gene links impulsive behavior to binge drinking in teens

Scientists clarify molecular mechanism of Visomitin drug

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