Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Findings of a preliminary study published in The Lancet Respiratory Medicine suggest that a patient’s own bone-marrow stromal (stem) cells could be used to treat multidrug-resistant (MDR) and extensively-drug (XDR) tuberculosis.

10 Jan 2014

Researchers deploy potential new weapon against HIV

Researchers at the UNC School of Medicine have deployed a potential new weapon against HIV - a combination therapy that targets HIV-infected cells that standard therapies cannot kill.

10 Jan 2014

Synta initiates three multicenter trials to evaluate ganetespib with chemotherapy for AML and MDS

Synta Pharmaceuticals Corp. today announced the initiation of three multicenter, randomized trials supported by the Leukemia & Lymphoma Research Fund and Cancer Research UK, evaluating ganetespib in combination with chemotherapy in first-line treatment of patients with AML and high risk MDS.

10 Jan 2014

Researchers develop personalized tool to predict likelihood of prostate cancer overdiagnosis

Studies have found that prostate cancer is overdiagnosed in up to 42 percent of cases, prompting men to receive unnecessary treatment that can cause devastating side effects, including impotence and incontinence.

9 Jan 2014

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Biogen Idec and Sangamo BioSciences, Inc. announced today an exclusive worldwide collaboration and license agreement focused on the development of therapeutics for hemoglobinopathies, inherited conditions that result from the abnormal structure or underproduction of hemoglobin.

9 Jan 2014

Immune tolerance to grafts of muscle, bone and skin could free recipients from lifelong immunosuppression

Massachusetts General Hospital investigators have made an important step towards greater availability of hand transplants, face transplants and other transplants involving multiple types of tissue.

9 Jan 2014

IDMC recommends early stopping of Phase 3 study of ibrutinib in treatment of CLL/SLL

Janssen-Cilag International NV today announced the early stopping of PCYC-1112-CA, the Phase 3 study of ibrutinib in the treatment of Chronic Lymphocytic Leukemia and Small Lymphocytic Lymphoma, based on the recommendation of an Independent Data Monitoring Committee, which concluded that the study showed a significant difference in progression-free survival as compared to the control, the primary endpoint of the study.

8 Jan 2014

Notre Dame, Loyola partner to provide direct support for revolutionary new cancer research

Two research powerhouses, Loyola University Chicago and the University of Notre Dame, are joining forces in a multidisciplinary cancer research collaboration.

8 Jan 2014

EC grants approval for ABRAXANE in combination with gemcitabine for metastatic pancreatic cancer

Celgene International Sàrl, a wholly-owned subsidiary of Celgene Corporation, today announced that the European Commission has granted approval for ABRAXANE (paclitaxel formulated as albumin bound nanoparticles, or nab-paclitaxel) in combination with gemcitabine for first-line treatment of adult patients with metastatic adenocarcinoma of the pancreas, or metastatic pancreatic cancer.

7 Jan 2014

DePuy Synthes Spine announces the U.S. launch of new tissue implant for spine fusion surgery

DePuy Synthes Spine, in collaboration with DePuy Synthes Biomaterials, announced today the U.S. launch of CONFORM SHEET, a hydrated, pliable and totally demineralized cancellous bone matrix that fills voids during posterolateral spinal fusion surgery and provides a natural scaffold for new bone formation.

7 Jan 2014

DePuy Synthes develops CONFORM SHEET allograft implant for spinal fusion surgery

DePuy Synthes Spine, in collaboration with DePuy Synthes Biomaterials, announced today the U.S. launch of CONFORM SHEET™, a hydrated, pliable and totally demineralized cancellous bone matrix that fills voids during posterolateral spinal fusion surgery and provides a natural scaffold for new bone formation.

7 Jan 2014

Diet high in fibre may ward off asthma

The Western diet probably has more to do with the asthma epidemic than has been assumed so far because developing asthma is related to the amount of fruit and vegetables consumed. Gut bacteria ferment the dietary fibres contained in them and fatty acids enter the blood as a result, influencing the immune response in the lungs. This has been shown by a research project funded by the Swiss National Science Foundation (SNSF).

6 Jan 2014

City of Hope to offer radiation oncology services to patients in the Arcadia area

City of Hope and Methodist Hospital of Southern California have reached an agreement in which City of Hope will acquire the hospital's radiation oncology service in Arcadia. The acquisition will expand access to City of Hope's renowned expertise in radiation therapy and will provide additional convenience for patients seeking specialized cancer services.

2 Jan 2014

FDA removes partial clinical hold on Cell Therapeutics' Tosedostat aminopeptidase inhibitor

Cell Therapeutics, Inc. (CTI) today announced that it has received notification from the U.S. Food and Drug Administration (FDA) that the partial clinical hold on tosedostat (IND 075503) has been removed and all studies underway may continue.

2 Jan 2014

Cardio3 BioSciences to participate in forthcoming Annual JP Morgan Healthcare Conference

Cardio3 BioSciences, a leader in the discovery and development of regenerative, protective and reconstructive therapies for the treatment of cardiac diseases, announces its participation in the forthcoming Annual JP Morgan Healthcare Conference in San Francisco, on January 13 to 16, 2014.

30 Dec 2013

Researchers report new gene delivery method that targets tumor blood vessels

Working in mice, researchers at Washington University School of Medicine in St. Louis report developing a gene delivery method long sought in the field of gene therapy: a deactivated virus carrying a gene of interest that can be injected into the bloodstream and make its way to the right cells.

24 Dec 2013

Key questions to ask about bone marrow transplants

Those who have leukemia, lymphoma or other blood cancer diseases might have heard about bone marrow transplant as a potential treatment. As with any serious procedure, it is important to have all questions answered by a physician before any decision is made.

20 Dec 2013

Cells grown in ISS could help patients recover from stroke, says Mayo Clinic researcher

Abba Zubair, M.D., Ph.D, believes that cells grown in the International Space Station could help patients recover from a stroke, and that it may even be possible to generate human tissues and organs in space. He just needs a chance to demonstrate the possibility.

19 Dec 2013

MSCs isolated from MS patients have decreased suppressive function

Multiple sclerosis, an inflammatory autoimmune disease affecting more than one million people worldwide, is caused by an immune reaction to myelin proteins, the proteins that help form the myelin insulating substance around nerves. Demyelination and MS are a consequence of this immune reaction. Bone marrow mesenchymal stem cells have been considered as an important source for cell therapy for autoimmune diseases such as MS because of their immunosuppressive properties.

18 Dec 2013

Arizona scientists investigate intriguing effects of spaceflight on microbial pathogens

At Arizona State University's Biodesign Institute, Cheryl Nickerson and her team have been investigating the intriguing effects of spaceflight on microbial pathogens.

17 Dec 2013

Bone Marrow News and Research

Further Reading

Patient's own bone-marrow stromal cells could treat multi-drug resistant TB

Researchers deploy potential new weapon against HIV

Synta initiates three multicenter trials to evaluate ganetespib with chemotherapy for AML and MDS

Researchers develop personalized tool to predict likelihood of prostate cancer overdiagnosis

Biogen Idec, Sangamo BioSciences partner to develop therapeutics for hemoglobinopathies

Immune tolerance to grafts of muscle, bone and skin could free recipients from lifelong immunosuppression

IDMC recommends early stopping of Phase 3 study of ibrutinib in treatment of CLL/SLL

Notre Dame, Loyola partner to provide direct support for revolutionary new cancer research

EC grants approval for ABRAXANE in combination with gemcitabine for metastatic pancreatic cancer

DePuy Synthes Spine announces the U.S. launch of new tissue implant for spine fusion surgery

DePuy Synthes develops CONFORM SHEET allograft implant for spinal fusion surgery

Diet high in fibre may ward off asthma

City of Hope to offer radiation oncology services to patients in the Arcadia area

FDA removes partial clinical hold on Cell Therapeutics' Tosedostat aminopeptidase inhibitor

Cardio3 BioSciences to participate in forthcoming Annual JP Morgan Healthcare Conference

Researchers report new gene delivery method that targets tumor blood vessels

Key questions to ask about bone marrow transplants

Cells grown in ISS could help patients recover from stroke, says Mayo Clinic researcher

MSCs isolated from MS patients have decreased suppressive function

Arizona scientists investigate intriguing effects of spaceflight on microbial pathogens

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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