Laboratory News and Research

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VARI, Gentel Biosciences receive U.S. Patent for new glycan detection technology

Gentel Biosciences, a leader in proteomics tools, and Van Andel Research Institute, a biomedical research institute, jointly announce today the granting of U.S. Patent 7,838,634 for a new method to profile changes in the glycosylation of proteins captured on the surface of an antibody array slide. Gentel first obtained an exclusive right to commercialize the technology in 2006.

25 Mar 2011

HDL, BG Medicine to offer galectin-3 testing services for patients with heart failure

Health Diagnostic Laboratory, Inc. and BG Medicine, Inc., announced today an agreement under which HDL, Inc. will offer galectin-3 testing services based on the BG Medicine Galectin-3 Test.

25 Mar 2011

Mouse sperm created in lab: Hope for male infertility

In a scientific breakthrough, researchers report that they've grown mouse sperm from testicular tissue in the laboratory, a development that could advance the field of infertility in human males. Although still proven in mice, “this is a small but important step in understanding how sperm are formed, which may, in time, lead to us being able to grow human sperm in the laboratory,” said Dr. Allan Pacey, senior lecturer in andrology at the University of Sheffield in England, who is familiar with the study results.

24 Mar 2011

Biotage introduces new system for microwave-assisted peptide synthesis

Biotage® (STO: BIOT), a supplier of tools and technology for medicinal, analytical and peptide chemistry, introduced the Biotage Initiator Peptide Workstation for manual microwave-assisted peptide synthesis. The Workstation utilizes a unique microwave peptide vial available in two sizes; 2-5 mL for 75-150 μmol scale or 10-20 mL for 250-500 μmol scale synthesis.

24 Mar 2011

Immune system misinterprets threats and attacks body's own cells and tissue

Many chronic diseases are the result of the body's immune system mistakenly perceiving that the body is under attack from foreign bodies. A counterattack is then launched - an inflammatory response meant to vanquish the intruder. In reality, the immune system has misinterpreted the threat and is actually attacking the body's own cells and tissue.

24 Mar 2011

Molecular Therapy journal publishes Mirna's new tumor suppressor miRNA mimics data

Mirna Therapeutics, Inc. announced today the publication of new results in the journal Molecular Therapy demonstrating how a neutral lipid emulsion facilitates the systemic delivery of tumor suppressor miRNA mimics and reduces the tumor burden in the lungs of mice.

24 Mar 2011

Researchers create new computational model to understand animal cell behavior

Biological systems, including cells, tissues and organs, can function properly only when their parts are working in harmony. These systems are often dauntingly complex: Inside a single cell, thousands of proteins interact with each other to determine how the cell will develop and respond to its environment.

24 Mar 2011

New research provides evidence that brain's sensory recalibration can occur instantly

New research provides the first evidence that sensory recalibration - the brain's automatic correcting of errors in our sensory or perceptual systems - can occur instantly.

24 Mar 2011

Sequencing mouse cancer genome reveals mutations driving cancer in humans

Scientists who pioneered sequencing the genomes of cancer patients to find novel genetic changes at the root of the disease now have turned their attention to a laboratory workhorse — a mouse.

24 Mar 2011

Brain's pleasure and reward circuitry gets a big boost after a sleepless night

A sleepless night can make us cranky and moody. But a lesser known side effect of sleep deprivation is short-term euphoria, which can potentially lead to poor judgment and addictive behavior, according to new research from the University of California, Berkeley.

24 Mar 2011

Aptiv Solutions, Cancer Genetics partner to deliver comprehensive solutions for clinical trials in oncology

Aptiv Solutions and Cancer Genetics, Inc. (CGI) have formed a strategic partnership focused on delivering comprehensive solutions to biopharmaceutical and medical device firms conducting clinical trials for oncology therapeutics.

24 Mar 2011

Researchers create hiPS-RPE cells to treat age-related macular degeneration

The notion of transplanting adult stem cells to treat or even cure age-related macular degeneration has taken a significant step toward becoming a reality. In a study published today in Stem Cells, Georgetown University Medical Center researchers have demonstrated, for the first time, the ability to create retinal cells derived from human-induced pluripotent stem cells that mimic the eye cells that die and cause loss of sight.

24 Mar 2011

Gut bacteria and state of immune system influence personality

Researchers at McMaster University discovered that the "cross-talk" between bacteria in our gut and our brain plays an important role in the development of psychiatric illness, intestinal diseases and probably other health problems as well including obesity.

24 Mar 2011

Oramed reports successful completion of ORMD-0801 oral insulin toxicity study

Oramed Pharmaceuticals Inc., a developer of oral delivery systems, announced today that it has successfully completed a comprehensive toxicity study for its flagship oral insulin capsule, ORMD-0801.

24 Mar 2011

MicroRNAs may play a key role in future medicine

Since their discovery in the 1990s, microRNAs have proven to play a complex role in normal and abnormal functioning of many organ systems. In the April issue of Translational Research, entitled "MicroRNAs: A Potential New Frontier for Medicine," an international group of medical experts explores several themes related to our current understanding of microRNAs and the role they may play in the future of medicine.

24 Mar 2011

Drug resistance tuberculosis concerns

According to a report released Wednesday, the World Health Organization revealed that drug resistant tuberculosis (TB) accounts for about 440,000 cases and 150,000 deaths worldwide each year. The WHO called for better diagnosis and more funding for treatment of the drug-resistant disease that's harder to cure.

23 Mar 2011

New study to provide better diagnoses for children with developmental disorders

A new UK study will provide better diagnoses for children with developmental disorders caused by changes in their genetic makeup. Scientists and clinicians will build a new national resource of genetic information and symptoms, based on data from 12,000 children who have a serious delay in their physical or mental development or are born with multiple malformations.

23 Mar 2011

Almac to launch new services for clinical trial patient management

Almac announced today that its Clinical Technologies business unit, a global leader in clinical trial management, will launch a suite of new services designed to improve patient compliance and retention in clinical trials.

23 Mar 2011

Researchers create nanosurfaces to seal leg prosthetics against bacteria entry

In recent years, researchers have worked to develop more flexible, functional prosthetics for soldiers returning home from battlefields in Afghanistan or Iraq with missing arms or legs. But even new prosthetics have trouble keeping bacteria from entering the body through the space where the device has been implanted.

23 Mar 2011

Jefferson begins patient recruitment for new clinical trail to prevent colon cancer

Thomas Jefferson University has started recruiting patients for a new National Cancer Institute-sponsored clinical trial to test whether the cholesterol-reducing drug rosuvastatin is effective in the prevention of recurrent colon cancer.

23 Mar 2011