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AstraZeneca to present Phase III CVOT DECLARE-TIMI 58 results at AHA Scientific Sessions

AstraZeneca will present 20 abstracts including a late-breaking oral presentation on the full results from the Phase III cardiovascular outcomes trial DECLARE -TIMI 58, the broadest SGLT2 inhibitor CVOT conducted to date, as well as new research from the Company's Cardiovascular, Renal & Metabolism therapy area at the American Heart Association Scientific Sessions, November 10-12, 2018, in Chicago, Illinois, USA.

1 Nov 2018

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

A study in mice has shown that it may be possible to detect the early signs of atherosclerosis, which leads to blocked arteries, by looking at how cells in our blood vessels change their function.

1 Nov 2018

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Genentech, a member of the Roche Group , announced today that the randomized Phase III CLL14 study, which evaluated fixed-duration Venclexta® in combination with Gazyva® in people with previously untreated chronic lymphocytic leukemia and co-existing medical conditions, met its primary endpoint and showed a statistically significant reduction in the risk of disease worsening or death compared to standard-of-care Gazyva plus chlorambucil.

1 Nov 2018

Researchers uncover link between RNA abnormalities and multiple myeloma progression

Multiple myeloma is the second most common type of blood cancer where cancer cells accumulate in the bone marrow, crowding out healthy blood cells.

1 Nov 2018

New study to evaluate human immune system's response to influenza

The key to lasting protection against influenza may be in your bones. The cells that naturally protect you against illness originate and live in your bone marrow - and that is one spot where scientists will be looking to understand the human immune system's response to influenza in a groundbreaking new study led by the Human Vaccines Project.

1 Nov 2018

Researchers cross-reference historical divergence of Aedes aegypti populations

The BioScience Talks podcast features discussions of topical issues related to the biological sciences. Mosquito-borne diseases have plagued humanity for centuries, and a prolific offender has been Aedes aegypti, commonly known as the "yellow fever mosquito."

1 Nov 2018

High blood pressure caused by specific signaling from the brain promotes heart disease

About 6 million Australians aged 18 years and over have high blood pressure. Of these, more than two thirds had uncontrolled or unmanaged high blood pressure (not taking medication), representing 4 million adult Australians.

1 Nov 2018

Researchers discover biomarker for most common type of heart failure

A team led by a Cedars-Sinai physician-scientist has discovered a biomarker--a protein found in the blood--for the most common type of heart failure, a new study published today in JAMA Cardiology shows.

1 Nov 2018

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

A cancer therapy based on fusing two types of cells into a single unit shows promise in strengthening existing treatments for acute myeloid leukemia. The approach joins blood platelets that carry cancer drugs with stem cells that guide the platelets into bone marrow where leukemia begins.

31 Oct 2018

Cytokine levels could predict autoimmune reactions to cancer immunotherapy

The development of immunotherapy, which mobilizes the body's own immune system to destroy cancer cells, is one of the greatest advances in cancer treatment, but immunotherapy can cause harm to healthy tissue in some patients.

31 Oct 2018

Scientists identify 'skeleton key' for congenital kidney disease research

Scientists in Japan have found a 'skeleton key' for congenital kidney disease research. Using iPS cells generated from the skin cells of a patient with a nephrin mutation, Kumamoto University scientists have successfully developed kidney tissue that exhibits the early stages of congenital kidney disease.

31 Oct 2018

Researchers identify active stem cells in “resting zone” of cartilage

Researchers have discovered active chondrocytes within cartilage. The finding could help scientists understand bone abnormalities.

31 Oct 2018

In swing districts, Republicans may pay for having tried to reverse the health law

Not long ago many voters knew little about Tom MacArthur. A low-key moderate Republican congressman in a district that twice went for Barack Obama, he burnished his reputation as the guy who worked with Democrats to help rebuild in the years after Hurricane Sandy.

31 Oct 2018

New software may enable early detection of arteriosclerosis

Arteriosclerosis is one of the widespread diseases. If the blood is no longer pumped properly through the veins, a heart attack or stroke may be the consequence. In most cases, the disease is only diagnosed at an advanced stage.

31 Oct 2018

3 Harvard scientists receive Allen awards for work in neuroimmunology, developmental biology, cancer

Three Harvard Medical School scientists have received the prestigious Allen Distinguished Investigator awards for their work in the fields of neuroimmunology, developmental biology and cancer.

31 Oct 2018

Study on how blood clots form and clear could make pancreatic cancer more treatable

You're experiencing jaundice, abdominal pain or constipation. And by then, you may be too late. Pancreatic cancer symptoms often arrive after the cancer has already spread, making the disease one of the leading causes of cancer deaths in the U.S.

31 Oct 2018

University of Missouri receives NIH grant for continued operation of NSRRC

The University of Missouri has received $7.229 million for continued operation of the National Swine Resource and Research Center.

31 Oct 2018

Study shows how machinery within immune system activates T cells to attack cancer

In just a few years, CAR T-cell and other adoptive T-cell therapies have emerged as among the most promising forms of cancer immunotherapy.

31 Oct 2018

Scientists describe novel conjugates made from antibodies and protein inhibitor

Linking therapeutically active molecules to specific antibodies can help to pilot them to their designated targets and minimize side effects--especially when treating tumors. In the journal Angewandte Chemie, scientists have now described novel conjugates made from antibodies and a kinesin spindle protein inhibitor.

31 Oct 2018

Dogs trained to sniff out malaria

It is already known that dogs with their sharp noses can sniff out a host of human diseases including cancers.

31 Oct 2018

Blood News and Research

AstraZeneca to present Phase III CVOT DECLARE-TIMI 58 results at AHA Scientific Sessions

Observing functional changes of cells in blood vessels may help detect early signs of atherosclerosis

Phase III CLL14 study evaluating Venclexta plus Gazyva to treat CLL meets its primary endpoint

Researchers uncover link between RNA abnormalities and multiple myeloma progression

New study to evaluate human immune system's response to influenza

Researchers cross-reference historical divergence of Aedes aegypti populations

High blood pressure caused by specific signaling from the brain promotes heart disease

Researchers discover biomarker for most common type of heart failure

Two-cells-in-one combo therapy shows promise in strengthening leukemia treatment

Cytokine levels could predict autoimmune reactions to cancer immunotherapy

Scientists identify 'skeleton key' for congenital kidney disease research

Researchers identify active stem cells in “resting zone” of cartilage

In swing districts, Republicans may pay for having tried to reverse the health law

New software may enable early detection of arteriosclerosis

3 Harvard scientists receive Allen awards for work in neuroimmunology, developmental biology, cancer

Study on how blood clots form and clear could make pancreatic cancer more treatable

University of Missouri receives NIH grant for continued operation of NSRRC

Study shows how machinery within immune system activates T cells to attack cancer

Scientists describe novel conjugates made from antibodies and protein inhibitor

Dogs trained to sniff out malaria

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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