Biochemistry News and Research

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Slugs inspire a surgical bio glue

Slugs secrete biological defensive mucus that has now inspired a new type of surgical glue, prepared by researchers. This “bio-glue” has three main properties, it can move with the body, it is incredibly strong and it can stick to wet surfaces. The results of this breakthrough are published this week in the journal Science.

27 Jul 2017

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

How can six and half feet of DNA be folded into the tiny nucleus of a cell? Researchers funded by the National Institutes of Health have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity.

27 Jul 2017

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

New research suggests that a man-made cousin of a small molecule found in olive oil can disrupt the hunger-signaling pathway.

27 Jul 2017

Researchers discover direct link between calcium and cholesterol

It's well known that calcium is essential for strong bones and teeth, but new research shows it also plays a key role in moderating another important aspect of health—cholesterol.

26 Jul 2017

New compound takes positive step toward creating drug for melanoma

While past attempts to treat melanoma failed to meet expectations, an international team of researchers are hopeful that a compound they tested on both mice and on human cells in a petri dish takes a positive step toward creating a drug that can kill melanoma cancer cells without harming nearby healthy cells.

26 Jul 2017

CUMC researchers capture first snapshot of key brain receptor in action

Columbia University Medical Center researchers have captured the first three-dimensional snapshots of the AMPA-subtype glutamate receptor in action. The receptor, which regulates most electrical signaling in the brain, is involved in several important brain activities, including memory and learning.

24 Jul 2017

Scientists unlock secrets of indestructible virus to create super-durable materials

It's like the Superman of viruses, astonishingly tough and able to survive in an environment that would dissolve flesh and bone. And now scientists have unlocked the secrets of its indestructibility, potentially allowing them to harness its remarkable properties to create super-durable materials and better treat disease.

19 Jul 2017

Two cell types partner to protect pancreatic tumors from immune attack

Two cell types work together to protect pancreatic tumors from destruction by the immune system. But, blocking this partnership may restore the system's ability to attack these same tumor cells.

19 Jul 2017

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

Chemical compounds called cannabinoids are found in marijuana and also are produced naturally in the body from omega-3 fatty acids.

18 Jul 2017

Research finding could pave way for novel compounds to tackle bacterial resistance

Bacteria or 'superbugs' that have adapted to resist multiple antibiotics are responsible for around 700,000 deaths globally a year; new types of antibiotics are urgently needed.

18 Jul 2017

Scientists gain new insights into protein network that regulates programmed cell death

Researchers use a simplified model of a protein network to explain how apoptosis is regulated, whose malfunction is linked to cancer and neurodegenerative diseases.

14 Jul 2017

Cellular antennae play key role in muscle-to-fat transformation

Like it or not, as we age, our muscle cells are slowly exchanged, one by one, for fat cells. This process quickens when we injure a muscle, and an extreme form of this process is also seen in muscle-wasting diseases such as Duchenne muscular dystrophy (DMD).

13 Jul 2017

Biochemistry News and Research

Slugs inspire a surgical bio glue

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

Synthetic molecule can disrupt hunger-signaling pathway, research suggests

Researchers discover direct link between calcium and cholesterol

New compound takes positive step toward creating drug for melanoma

CUMC researchers capture first snapshot of key brain receptor in action

Scientists unlock secrets of indestructible virus to create super-durable materials

Two cell types partner to protect pancreatic tumors from immune attack

Study shows how omega-3 fatty acids can produce same medicinal qualities as marijuana

Research finding could pave way for novel compounds to tackle bacterial resistance

Scientists gain new insights into protein network that regulates programmed cell death

Cellular antennae play key role in muscle-to-fat transformation

Potential vaccines could protect developing fetus from Zika virus, UTMB study shows

Aflatoxin detection in milk research, the SYMPHONY project, is completed

Targeting acid metabolite reduces size and spread of breast cancer

UMMS scientists design human protein-based tumor-targeting MRI contrast agent

UT Southwestern researchers develop novel chemical reaction that could accelerate drug development

Scientists shed new light on how tau protein transitions from liquid state to solid tangles

Researchers discover how new molecular scissors unzip and cleave DNA with high accuracy

Lower calorie intake by host may increase chances of surviving malaria

Biochemical Assays for Efficient Hit Prioritization After Screening eBook

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Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo