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Investigators find group of drugs to treat heart attacks and cancer metastasis

Massachusetts General Hospital (MGH) investigators may have found a way to solve a problem that has plagued a group of drugs called ligand-mimicking integrin inhibitors, which have the potential to treat conditions ranging from heart attacks to cancer metastasis.

24 Mar 2014

Biogen Idec's ALPROLIX gets Health Canada approval for hemophilia B

Today Biogen Idec announced that Health Canada has approved ALPROLIX [Coagulation Factor IX (Recombinant), Fc Fusion Protein], for the control and prevention of bleeding episodes and routine prophylaxis in adults, and children aged 12 and older, with hemophilia B.

21 Mar 2014

Cardiac arrest during childbirth may be 2 times more common than previously reported

Although cardiac arrest during childbirth is rare, it may be two times more common than previously reported in the literature, suggests the first large U.S. study on the potentially deadly condition published in the April issue of Anesthesiology.

19 Mar 2014

Lung ultrasound could help determine if pregnant woman with preeclampsia is at risk for respiratory failure

18 Mar 2014

New case study reveals how to safely switch between anticoagulants for stroke prevention

With the availability of newer oral anticoagulants, the latest online case study from NPS MedicineWise helps health professionals navigate this changing area and understand the range of treatment options for managing stroke prevention in people with non-valvular atrial fibrillation.

18 Mar 2014

Study finds higher readmission rates for same-day total joint replacement surgery

As the effectiveness of anesthesia, pain management and rehabilitation continues to improve, more orthopaedic procedures are being done on an outpatient basis. In a new research study presented today at the 2014 Annual Meeting of the American Academy of Orthopaedic Surgeons, same-day total joint replacement (TJR) patient outcomes were comparable to those of patients admitted to the hospital and staying at least one night following surgery.

14 Mar 2014

Regado receives Fast Track designation from FDA for REG1

Regado Biosciences, Inc., a biopharmaceutical company focused on the development of actively controllable therapeutics, today announced that the United States Food and Drug Administration has designated REG1 for anticoagulant therapy to be used in patients with coronary artery disease during percutaneous coronary interventions (PCI) as a Fast Track development program.

10 Mar 2014

Risk-based approach for screening men at increased risk of prostate cancer

The UK needs to invest in testing for those men most at risk of prostate cancer rather than follow a cast-the-net-wide approach targeting the whole population, a leading scientist from The University of Manchester - part of Manchester Cancer Research Centre - has argued at an international conference this week.

From The University of Manchester 10 Mar 2014

CSI's new Diamondback Peripheral 60cm systems receive FDA clearance for PAD treatment

Cardiovascular Systems, Inc., announced today it has received FDA clearance of its new Diamondback 360 60cm Peripheral Orbital Atherectomy Systems (OAS) for the treatment of peripheral arterial disease (PAD).

10 Mar 2014

New study assesses effectiveness of two surgical treatments for ectopic pregnancy

A new study from Wake Forest Baptist Medical Center looked at pregnancy outcomes in regards to the two surgical treatments for ectopic pregnancy -- salpingectomy, in which the affected fallopian tube is removed, or salpingotomy, in which the tube is preserved.

6 Mar 2014

Report highlights benefits of different access approach to treat uterine fibroids

Interventional radiologists have devised a new way to access a woman's fibroids-by flipping her wrist and treating via an arm not groin artery-to nonsurgically shrink noncancerous growths in the muscular wall of the uterus. Researchers found this to be less painful and traumatic for women, allowing them to immediately sit up and move after uterine fibroid embolization (UFE)-with no overnight stay, according to a March article in the Society of Interventional Radiology's flagship publication, the Journal of Vascular and Interventional Radiology.

6 Mar 2014

Loyola surgeon successfully performs operation on patient suffering from rare disorder

Jarely Sanchez is an affectionate, energetic little girl who loves ballet. "Everyone she meets, she connects with," said her father, Jose Angel Ulloa. "She's like a magnet." But for more than a week, the three-year-old girl wasn't herself.

4 Mar 2014

LFB SA initiates Phase 3 program for human Factor VIIa in patients with congenital hemophilia

LFB SA, through its rEVO Biologics subsidiary, announced today initiation of the global Phase 3 program for LR769, a novel recombinant form of human Factor VIIa, in patients with congenital hemophilia A or B with inhibitors.

4 Mar 2014

Protamine antidote can be effective in reversing low-molecular-weight heparin

Low-molecular-weight heparin is commonly used in surgeries to prevent dangerous blood clots. But when patients experience the other extreme - uncontrolled bleeding - in response to low-molecular-weight heparin, there is no antidote.

4 Mar 2014

OPKO Health consolidated revenues increase about 30% to $20.7 million in Q4 2013

OPKO Health, Inc., a multi-national biopharmaceutical and diagnostics company, today reported operating and financial results for its 2013 fourth quarter and full year ended December 31, 2013.

4 Mar 2014

Tooth extraction before heart surgery carries risks

Dental extraction before cardiac surgery may not be as benign a procedure as some clinicians might think, with review findings showing that it is associated with major adverse outcomes.

28 Feb 2014

Motesanib boosts carboplatin/paclitaxel efficacy in NSCLC

Adding motesanib to carboplatin/paclitaxel significantly improves overall survival in Asian patients with nonsquamous non-small-cell lung cancer compared with carboplatin/paclitaxel alone, researchers report.

27 Feb 2014

Scientific Statement details latest evidence for diagnosis and treatment of fibromuscular dysplasia

A vascular disease called fibromuscular dysplasia, which can cause high blood pressure, kidney failure, stroke and other symptoms -- mostly in women -- is "poorly understood by many healthcare providers," according to a Scientific Statement from the American Heart Association.

27 Feb 2014

Patients with dental extractions before cardiac surgery still at risk for poor outcomes

To pull or not to pull? That is a common question when patients have the potentially dangerous combination of abscessed or infected teeth and the need for heart surgery.

27 Feb 2014

Altheus Therapeutics completes dosing of ZA201 in Phase 2 trial of Zoenasa for ulcerative colitis

Altheus Therapeutics, Inc., announced completion of dosing in ZA201, a double-blind, active-controlled Phase 2 trial evaluating the efficacy and safety of Zoenasa® Rectal Gel versus mesalamine enema in 120 patients with left-sided ulcerative colitis.

27 Feb 2014

Bleeding News and Research

Investigators find group of drugs to treat heart attacks and cancer metastasis

Biogen Idec's ALPROLIX gets Health Canada approval for hemophilia B

Cardiac arrest during childbirth may be 2 times more common than previously reported

Lung ultrasound could help determine if pregnant woman with preeclampsia is at risk for respiratory failure

New case study reveals how to safely switch between anticoagulants for stroke prevention

Study finds higher readmission rates for same-day total joint replacement surgery

Regado receives Fast Track designation from FDA for REG1

Risk-based approach for screening men at increased risk of prostate cancer

CSI's new Diamondback Peripheral 60cm systems receive FDA clearance for PAD treatment

New study assesses effectiveness of two surgical treatments for ectopic pregnancy

Report highlights benefits of different access approach to treat uterine fibroids

Loyola surgeon successfully performs operation on patient suffering from rare disorder

LFB SA initiates Phase 3 program for human Factor VIIa in patients with congenital hemophilia

Protamine antidote can be effective in reversing low-molecular-weight heparin

OPKO Health consolidated revenues increase about 30% to $20.7 million in Q4 2013

Tooth extraction before heart surgery carries risks

Motesanib boosts carboplatin/paclitaxel efficacy in NSCLC

Scientific Statement details latest evidence for diagnosis and treatment of fibromuscular dysplasia

Patients with dental extractions before cardiac surgery still at risk for poor outcomes

Altheus Therapeutics completes dosing of ZA201 in Phase 2 trial of Zoenasa for ulcerative colitis

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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