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New nanoenzyme may help increase anti-tumor immunity

Theoretically, our immune system could detect and kill cancer cells. Unfortunately, tumors are well armed to fight these attacks. Despite modern cancer treatments, metastases and relapses remain a major problem.

25 Oct 2019

TB is not a life-long infection in most people

A new analysis challenges the longstanding notion that tuberculous infection is a life-long infection that could strike at any time and cause tuberculosis. Based on a review of clinical studies, researchers from the Perelman School of Medicine at the University of Pennsylvania and colleagues show that people who test positive with immunologic TB skin or blood tests rarely develop TB.

25 Oct 2019

Study pinpoints cell types linked to age-related macular degeneration

Age-related macular degeneration is one of the leading causes of blindness in the elderly, affecting more than 2 million people in the United States and leading to progressive loss of central vision.

25 Oct 2019

Scientists uncover how brain cells respond to and recover from lack of nutrition

We all know that food is essential to healthy development of the brain and body, especially in the earliest stages of life. But exactly how early brain growth is affected by nutrition is not as well understood, especially on a cellular level.

25 Oct 2019

Researchers discover how the body repairs damaged DNA

Researchers from the University of Copenhagen have made an extraordinary discovery in how the body repairs damaged DNA, which can lead to better understanding and management of diseases such as cancer.

25 Oct 2019

Researchers use 3D electron microscopy to unravel dense networks in the cerebral cortex

Unlike any other organ, our brains contain extremely densely packed networks of membranous cables that are used by our about 86 billion nerve cells for communication amongst each other.

24 Oct 2019

Scientists pinpoint epigenetic differences in the way lupus affects black women

Scientists at the HudsonAlpha Institute for Biotechnology have pinpointed epigenetic differences in the way lupus affects black women compared to other lupus patients, revealing important mechanics of the puzzling disease.

24 Oct 2019

Insights about the sweet receptor could lead to better-tasting food

Whether it's chocolate cake or pasta sauce, the sensation of sweetness plays a major role in the human diet and the perception of other flavors.

24 Oct 2019

Ultraviolet B light is good for the gut microbiome

A small study published in the journal Frontiers in Immunologyon October 24, 2019, shows that exposure to ultraviolet B (UVB) light, which is commonly achieved through sunlight exposure, can trigger specific beneficial changes in the gut microbiome, which are dependent on the preceding serum levels of vitamin D.

24 Oct 2019

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

A new study by Weill Cornell Medicine and Cornell University has come up with more explanations of how gut microbes communicate with the brain neurons. The study, published in the journal Nature on October 23, 2019, examined the brains of mouse models and found that when the gut microbiome is significantly reduced, there are changes in gene expression in the brain’s microglial cells.

24 Oct 2019

High-salt diet may trigger dementia

We’ve all heard that taking too much salt can damage your blood vessels, and now a new study published in the journal Nature on October 23, 2019, says it’s true – a diet rich in salt reduces the levels of nitric oxide, which in turn alters the tau protein within the neuron, triggering a fall in cognitive processing by the brain.

24 Oct 2019

How does cancer look on day 1? Researchers collaborate to find out

Researchers from Britain and United States are working in collaboration to detect the earliest possible sign of cancer within the body and trace the alterations that lead to full blown cancer. This may help doctors detect cancer even before it is fully formed, the researchers hope.

24 Oct 2019

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

The survival of patients with pediatric acute lymphoblastic leukemia (ALL) has significantly improved in the last several decades. However, novel strategies to identify cases that are likely to respond poorly to treatment are still needed.

24 Oct 2019

Gene linked to schizophrenia likely confers risk for illness

Researchers have discovered in mice how one of the few genes definitively linked to schizophrenia, called SETD1A, likely confers risk for the illness. Mice genetically engineered to lack a functioning version of the enzyme-coding gene showed abnormalities in working memory, mimicking those commonly seen in schizophrenia patients.

24 Oct 2019

Researchers identify potential approach to stop growth of common brain tumor in children

University of North Carolina Lineberger Comprehensive Cancer Center researchers have identified a potential approach to stop the growth of the most common type of brain tumor in children.

24 Oct 2019

UA Little Rock receives $5.6 million DOD grant to advance bone regeneration technology

The U.S. Department of Defense has awarded the University of Arkansas at Little Rock a $5.6 million grant to advance the NuCress scaffold, a groundbreaking bone regeneration technology.

24 Oct 2019

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

A team of Gladstone scientists and their partners at Xyphos Biosciences, Inc. describe a new way of attacking cells infected by HIV in this week's issue of the journal Cell.

24 Oct 2019

Genetic variations linked to declines in blood oxygen levels during sleep identified

Researchers have identified 57 genetic variations of a gene strongly associated with declines in blood oxygen levels during sleep. Low oxygen levels during sleep are a clinical indicator of the severity of sleep apnea, a disorder that increases the risk of heart disease, dementia, and death.

24 Oct 2019

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Sarcomas - cancers that arise from transformed mesenchymal cells (a type of connective tissue) - are quite deadly. Gastrointestinal stromal tumors are the most common human sarcoma and are initiated by activating mutations in the KIT receptor tyrosine kinase.

24 Oct 2019

Vaccine for Lassa fever set to enter clinical testing in humans

There is currently no vaccine for the Lassa arenavirus, which causes Lassa fever. This hemorrhagic fever, endemic in West Africa, infects up to 300,000 people each year.

24 Oct 2019

Cell News and Research

New nanoenzyme may help increase anti-tumor immunity

TB is not a life-long infection in most people

Study pinpoints cell types linked to age-related macular degeneration

Scientists uncover how brain cells respond to and recover from lack of nutrition

Researchers discover how the body repairs damaged DNA

Researchers use 3D electron microscopy to unravel dense networks in the cerebral cortex

Scientists pinpoint epigenetic differences in the way lupus affects black women

Insights about the sweet receptor could lead to better-tasting food

Ultraviolet B light is good for the gut microbiome

Unhealthy gut microbiome reduces brain synaptic pruning, impairs learning

High-salt diet may trigger dementia

How does cancer look on day 1? Researchers collaborate to find out

Metabolite profiling during diagnosis helps identify poor treatment outcomes in ALL

Gene linked to schizophrenia likely confers risk for illness

Researchers identify potential approach to stop growth of common brain tumor in children

UA Little Rock receives $5.6 million DOD grant to advance bone regeneration technology

ConvertibleCAR immunotherapy can be used to attack HIV latent reservoir

Genetic variations linked to declines in blood oxygen levels during sleep identified

Study reveals novel druggable driver gene in human gastrointestinal stromal tumors

Vaccine for Lassa fever set to enter clinical testing in humans

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