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WINCS device can detect and measure serotonin levels in brain: Mayo Clinic

Mayo Clinic researchers have concluded that, through deep brain stimulation, a Wireless Instantaneous Neurotransmitter Concentration System can detect and measure serotonin levels in the brain. The findings suggest that in the future such measurements of serotonin may help establish a therapeutic mechanism of deep brain stimulation for psychiatric disease.

5 Feb 2011

Phase II results of VELCADE in patients with aggressive lymphoma published in Journal of Clinical Oncology

Millennium: The Takeda Oncology Company today announced that Phase II results of a clinical trial examining VELCADE (bortezomib) in patients with previously untreated aggressive lymphoma were published in the Journal of Clinical Oncology.

5 Feb 2011

U-M Medical School earns $368.7 million in NIH research funding during federal fiscal year 2010

University of Michigan Medical School physicians and scientists earned more than $368.7 million in National Institutes of Health research funding in federal fiscal year 2010, according to NIH data. In all, the School's faculty brought in $481.8 million in research funding from all sources in U-M fiscal year 2010.

5 Feb 2011

First mobile application is now available for clinicians to diagnose bleeding disorders

Novo Nordisk announced today the availability of Coags Uncomplicated – the first mobile application to assist in the diagnosis of bleeding disorders – created in partnership with Craig Kessler, MD, Professor of Medicine and Pathology and Director of the Coagulation Laboratory, Georgetown University Hospital, Lombardi Comprehensive Cancer Center.

5 Feb 2011

Anacor initiates dosing in AN2728 Phase 2b trial for psoriasis

Anacor Pharmaceuticals announced today that the first patient has been dosed in a Phase 2b trial of AN2728, a topical anti-inflammatory product candidate for the treatment of psoriasis. Psoriasis is a chronic inflammatory skin disease that affects approximately 7.5 million people in the United States and over 100 million people worldwide.

4 Feb 2011

Scientists discover how stressed cells boost thrombin production

In our not-so-distant evolutionary past, stress often meant imminent danger, and the risk of blood loss, so part of our body's stress response is to stock-pile blood-clotting factors. Scientists in the Molecular Medicine Partnership Unit, a collaboration between the European Molecular Biology Laboratory in Heidelberg, Germany, and the University of Heidelberg Medical Centre, have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin.

4 Feb 2011

Salk Institute receives $2.3 million CIRM grant for translational research on Parkinson's disease

The Salk Institute has been awarded a $2.3 million grant by the California Institute for Regenerative Medicine for translational research focusing on developing a novel stem cell based therapy for Parkinson's disease.

4 Feb 2011

Engineered cells take control of the cells and microenvironment following transplantation

In work that could jumpstart the promising field of cell therapy, in which cells are transplanted into the body to treat a variety of diseases and tissue defects, researchers at Brigham and Women's Hospital (BWH) have engineered cells that could solve one of the key challenges associated with the procedure: control of the cells and their microenvironment following transplantation.

4 Feb 2011

Lampreys may have dual immune defense system similar to that of humans

Biologists have discovered that primitive, predatory lampreys have structures within their gills that play the same role as the thymus, the organ where immune cells called T cells develop in mammals, birds and fish.

4 Feb 2011

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

Scientists in a collaboration between EMBL Heidelberg and the University of Heidelberg Medical Centre have discovered how stressed cells boost the production of the key blood-clotting factor, thrombin. Their work, published today in Molecular Cell, shows how cancer cells may be taking advantage of this process, and opens new possibilities for fighting back against cancer and septicaemia.

4 Feb 2011

Most Canadians want to do more to support cancer research

When it comes to cancer research, Canadians want to do more. A national survey released today in advance of World Cancer Day shows that more than half of Canadians 35 to 69 years of age feel cancer should be a top priority for health research. However, the survey also shows that a similar number do not know how to get involved in a way that could be helpful to other people.

4 Feb 2011

Queen's awarded £1.74 million grant to study microbiology of Cystic Fibrosis pulmonary infection

Scientists at Queen's University Belfast have begun work into improving the lives of thousands of Cystic Fibrosis sufferers thanks to the award of a £1.74 million US-Ireland Research and Development Partnership grant.

4 Feb 2011

How body's first line of defence distinguishes between microbes and own structures

This week, the highly-respected US Academy of Sciences journal (PNAS) published an article describing how the first line of defence of the human immune system distinguishes between microbes and the body's own structures.

4 Feb 2011

Research unmasks long sought stem cell origin of carcinoma

A constellation of different stem cell populations within our skin help it to cope with normal wear and tear. By constantly proliferating, the stem cells allow skin to replenish itself, allowing each cell to be replaced by a new one about once a month. But the normal cycle of division and death within one or more of these stem cell types can sometimes be derailed by genetic mishaps. Such events are believed to spawn carcinomas and other deadly skin cancers, which are the mostly frequently diagnosed cancers in the United States.

4 Feb 2011

Researchers identify regulatory defect that drives lupus

Researchers at Dana-Farber Cancer Institute in Cambridge, Mass., in collaboration with Jackson Laboratory scientists, have identified a regulatory defect that drives lupus.

4 Feb 2011

Cholesterol efflux capacity may protect against heart disease: Study

The discovery that high levels of high-density lipoprotein cholesterol are associated with reduced risk of cardiovascular disease has fostered intensive research to modify HDL levels for therapeutic gain. However, recent findings have called into question the notion that pharmacologic increases in HDL cholesterol levels are necessarily beneficial to patients.

4 Feb 2011

New discovery: miR-429 regulatory RNA may be effective in fighting ovarian cancer

Cancer researchers have discovered that a type of regulatory RNA may be effective in fighting ovarian cancer. Ovarian cancer isn't typically discovered until it's in the advanced stages, where it is already spreading to other organs and is very difficult to fight with chemotherapy.

4 Feb 2011

Kaiser Permanente receives $3 million CDC grant to continue SEARCH study for childhood diabetes

The Kaiser Permanente Southern California Department of Research & Evaluation has been awarded more than $3 million from the Centers for Disease Control and Prevention to continue the SEARCH for Diabetes in Youth Study for an additional five years to 2015.

4 Feb 2011

Data generated on Ion Torrent PGM sequencer to be presented at AGBT

Life Technologies Corporation, today announced that just six weeks following the launch of the Ion Torrent PGM sequencer, independent researchers will present data they generated with the system at the annual Advances in Genome Biology and Technology (AGBT) conference.

4 Feb 2011

Scientists reprogram marrow cells from patient with chronic myeloid leukemia

By coaxing healthy and diseased human bone marrow to become embryonic-like stem cells, a team of Wisconsin scientists has laid the groundwork for observing the onset of the blood cancer leukemia in the laboratory dish.

4 Feb 2011

Laboratory News and Research

WINCS device can detect and measure serotonin levels in brain: Mayo Clinic

Phase II results of VELCADE in patients with aggressive lymphoma published in Journal of Clinical Oncology

U-M Medical School earns $368.7 million in NIH research funding during federal fiscal year 2010

First mobile application is now available for clinicians to diagnose bleeding disorders

Anacor initiates dosing in AN2728 Phase 2b trial for psoriasis

Scientists discover how stressed cells boost thrombin production

Salk Institute receives $2.3 million CIRM grant for translational research on Parkinson's disease

Engineered cells take control of the cells and microenvironment following transplantation

Lampreys may have dual immune defense system similar to that of humans

Scientists discover how stressed cells boost production of key blood-clotting factor, thrombin

Most Canadians want to do more to support cancer research

Queen's awarded £1.74 million grant to study microbiology of Cystic Fibrosis pulmonary infection

How body's first line of defence distinguishes between microbes and own structures

Research unmasks long sought stem cell origin of carcinoma

Researchers identify regulatory defect that drives lupus

Cholesterol efflux capacity may protect against heart disease: Study

New discovery: miR-429 regulatory RNA may be effective in fighting ovarian cancer

Kaiser Permanente receives $3 million CDC grant to continue SEARCH study for childhood diabetes

Data generated on Ion Torrent PGM sequencer to be presented at AGBT

Scientists reprogram marrow cells from patient with chronic myeloid leukemia

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