Research News and Research

RSS

Exome sequencing unravels complex genetic diagnoses in growth disorders

In an article published in the Journal of Pediatrics, researchers based in Brazil describe the case of a nine-year-old boy admitted to hospital with multiple symptoms and overlapping conditions that made diagnosis difficult, such as short stature, thin tooth enamel (dental enamel hypoplasia), moderate mental deficiency, speech delay, asthma, mildly altered blood sugar, and a history of recurring infections in infancy.

16 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

Rabies in urban opossums signals health alert in São Paulo

A female White-eared opossum (Didelphis albiventris) found dead in 2021 in Bosque dos Jequitibás Park in the center of Campinas, one of the largest cities in São Paulo state, Brazil, died from rabies meningoencephalitis, according to a group of researchers at the University of São Paulo (USP) and Adolfo Lutz Institute (IAL), the regional reference laboratory, working with health professionals affiliated with public institutions in São Paulo city and Campinas.

16 Feb 2024

Genetic mechanism shields bacterial communities from viral threats

Like humans struggling to get through the COVID-19 pandemic, bacterial cells need social distancing to thwart viruses.

16 Feb 2024

Risk-reducing mastectomies lower breast cancer incidence and mortality in BRCA variant carriers

A study co-led by Professor Kelly Metcalfe of the Lawrence Bloomberg Faculty of Nursing, and researchers at the Familial Breast Cancer Research Unit at Women's College Hospital, finds risk-reducing mastectomies (RRM) in women with a BRCA1 or BRCA2 genetic variant, significantly reduces the risk of being diagnosed with breast cancer and lowers the probability of death.

16 Feb 2024

Optimizing chemotherapy for older adults with advanced cancer

Standard chemotherapy regimens, which are mostly based on testing in relatively young and healthy patients, may do more harm to older adults with cancer who often struggle with other health issues.

16 Feb 2024

Evaluating a machine learning tool for predicting hospital-acquired acute kidney injury

Hospital-acquired acute kidney injury (HA-AKI) is a common complication in hospitalized patients that can lead to chronic kidney disease and is associated with longer hospital stays, higher health care costs and increased mortality.

16 Feb 2024

Unlocking the brain's decision-making secrets for future insights

Researchers at Washington University School of Medicine in St. Louis have found important clues to how people make choices involving obtaining information about the future.

16 Feb 2024

FDA approves omalizumab for food allergy reactions based on NIH research

Today's Food and Drug Administration approval of a supplemental biologics license for the monoclonal antibody omalizumab (Xolair) highlights the vital role of the National Institutes of Health-supported research that underpins the FDA decision.

16 Feb 2024

Lockdown delays in melanoma diagnosis cost Europe £6bn and thousands of lives

Delays in diagnosing melanoma due to Covid-19 lockdown may have contributed to over 100,000 years of life lost across Europe and over £6bn in costs, mainly indirectly due to loss of productivity, finds a new study led by UCL and University Hospital of Basel researchers.

16 Feb 2024

Virginia Tech receives grant for improving rural wastewater pathogen detection

Testing wastewater to assess the spread of the COVID-19 virus became common and well-publicized during the pandemic, but it has been focused mostly on urban areas.

16 Feb 2024

Study links finger length ratio to oxygen metabolism efficiency in athletes

The efficiency of oxygen supply to tissues is a factor in the severity of important diseases such as Covid-19 and heart conditions.

16 Feb 2024

New standards for evaluating aging biomarkers unveiled

A new paper led by Harvard researchers has zeroed in on biomarkers of aging using omic data from population-based studies.

16 Feb 2024

Innovative immunotherapy targets rare melanoma subtypes

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.

16 Feb 2024

Study uncovers key genes and cell types that may affect pathogenesis of primary open-angle glaucoma

Study suggests CT imaging with automated AI system predicts EGFR genotype, identifying mutation status cost-effectively and non-invasively

Researchers developed an artificial intelligence (AI)-based predictive system (AIPS) model for the early detection of lung cancer by combining radiological, clinical, and genetic data.

16 Feb 2024