Anemia News and Research

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Anemia is a decrease in normal number of red blood cells (RBCs) or less than the normal quantity of hemoglobin in the blood. However, it can include decreased oxygen-binding ability of each hemoglobin molecule due to deformity or lack in numerical development as in some other types of hemoglobin deficiency. The three main classes of anemia include excessive blood loss (acutely such as a hemorrhage or chronically through low-volume loss), excessive blood cell destruction (hemolysis) or deficient red blood cell production (ineffective hematopoiesis). Anemia is the most common disorder of the blood. There are several kinds of anemia, produced by a variety of underlying causes. Anemia can be classified in a variety of ways, based on the morphology of RBCs, underlying etiologic mechanisms, and discernible clinical spectra, to mention a few.

Combining medications often best strategy to battle rheumatoid arthritis

For patients with rheumatoid arthritis, combining one well-known, lower cost synthetic drug with one of six biologic medications often works best to reduce joint swelling or tenderness, according to a new report funded by the Agency for Healthcare Research and Quality, part of the U.S. Department of Health and Human Services.

18 Dec 2007

Blood transfusions linked to surgery complications in women

Women die and get infections more often than men after heart surgery because they tend to receive more blood transfusions, which boost the risks of bad outcomes, according to a study published in the December Journal of Women's Health.

13 Dec 2007

Most carriers of Fanconi anemia genes are not at a higher risk of cancer

For almost 50 years, Fanconi anemia has been associated with leukemia. Not just among those who have the genetic disorder but among their family members, whose genes, they were told, made them highly susceptible to a variety of malignancies.

13 Dec 2007

Human hormone shows potential as new antidepressant agent

Novel treatment strategies for major depression with broader treatment success or a more rapid onset of action would have immense impact on public health, a new study published in the December 1st issue of Biological Psychiatry explains.

12 Dec 2007

Need for education for primary care physicians on rarely seen cancers

Many primary care physicians may lack the necessary knowledge when it comes to recognizing the signs, symptoms and making proper diagnoses in cases of blood cancers such as leukemia and lymphoma, a recent survey indicates.

10 Dec 2007

Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

Treating relapsed follicular lymphoma patients with a milder chemotherapy regimen before they receive a blood stem cell transplant from a donor resulted in long-term complete remission for 45 of 47 patients in a clinical trial, researchers at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology.

10 Dec 2007

Anemia drugs linked with leukemic transformation in patients with primary myelofibrosis

Mayo Clinic researchers have reported the discovery of a link between erythropoiesis-stimulating agents (ESAs) and leukemic transformation (conversion to leukemia) of the blood disorder myelofibrosis.

10 Dec 2007

Study results from Zolinza (vorinostat) in combination with bortezomib for multiple myeloma trial

Results from two investigational Phase I trials of ZOLINZA (vorinostat) in combination with bortezomib provide preliminary anti-tumor activity in patients with relapsed and/or refractory multiple myeloma.

10 Dec 2007

Reprogrammed stem cells cure sickle cell anaemia

Scientists in the U.S. have made a breakthrough in the fight against sickle cell anaemia, a blood disease caused by a defect in a single gene.

9 Dec 2007

Study questions impact of hemoglobin variations on mortality in dialysis patients

For patients with dialysis-related anemia, the risk of death is increased when hemoglobin levels remain persistently low over a period several months - not necessarily when they fluctuate over time, according to a study in the January Clinical Journal of the American Society of Nephrology.

5 Dec 2007

Scientists develop optical device that allows them to peer through the eyes of a mouse and monitor cells passing in bloodstream

A team of researchers from the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) and Harvard Medical School (HMS) have developed an optical device that allows them to peer through the eyes of a mouse and monitor the cells passing through its bloodstream.

4 Dec 2007

Study looks at blood transfusion outcomes in women

3 Dec 2007

Researchers find new way to transplant new blood-forming stem cells into bone marrow of mice

Researchers at the Stanford University School of Medicine have taken a small but significant step, in mouse studies, toward the goal of transplanting adult stem cells to create a new immune system for people with autoimmune or genetic blood diseases.

22 Nov 2007

Combining medications often best strategy to battle rheumatoid arthritis

For patients with rheumatoid arthritis, combining one well-known, lower-cost synthetic drug with one of six biologic medications often works best to reduce joint swelling or tenderness, according to a new report by researchers at the RTI International-University of North Carolina at Chapel Hill Evidence-based Practice Center, which is sponsored by the Agency for Healthcare Research and Quality.

19 Nov 2007

Human health, agriculture and the environment to benefit from bioengineering project at the University of Kent

Martin Warren, Professor of Biochemistry at the University of Kent’s Department of Biosciences, has been awarded over £750,000 from the Biotechnology and Biological Sciences Research Council for a study into biochemical pathways that could ultimately lead to improved health benefits for humans, as well as the development of important new technologies and products for agriculture and bioremediation (the use of plants or microorganisms to clean up pollution or contaminated material).

19 Nov 2007

New anemia measure predicts risk of death in dialysis patients

A new indicator of variations in hemoglobin level over time is a strong predictor of the risk of death among patients receiving dialysis for end-stage renal disease (ESRD), reports a study in the December Journal of the American Society of Nephrology.

15 Nov 2007

Anemia News and Research

Further Reading

Combining medications often best strategy to battle rheumatoid arthritis

Blood transfusions linked to surgery complications in women

Most carriers of Fanconi anemia genes are not at a higher risk of cancer

Human hormone shows potential as new antidepressant agent

Need for education for primary care physicians on rarely seen cancers

Mild chemo before stem cell transplant causes long-term remission of follicular lymphoma

Anemia drugs linked with leukemic transformation in patients with primary myelofibrosis

Study results from Zolinza (vorinostat) in combination with bortezomib for multiple myeloma trial

Reprogrammed stem cells cure sickle cell anaemia

Study questions impact of hemoglobin variations on mortality in dialysis patients

Scientists develop optical device that allows them to peer through the eyes of a mouse and monitor cells passing in bloodstream

Study looks at blood transfusion outcomes in women

Researchers find new way to transplant new blood-forming stem cells into bone marrow of mice

Combining medications often best strategy to battle rheumatoid arthritis

Human health, agriculture and the environment to benefit from bioengineering project at the University of Kent

New anemia measure predicts risk of death in dialysis patients

FDA strengthens warnings for erythropoiesis-stimulating agents

Chronic kidney disease common in U.S. - obesity, diabetes, hypertension and aging population contribute to increase

Minority patients prefer optical colonoscopy for colorectal cancer screening

Somalia experiencing huge increase in cases of visceral leishmaniasis

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