Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Study directly links common variants of Alzheimer's risk genes to atrophy

Two genetic variants previously linked to Alzheimer's disease have been more specifically tied to brain atrophy that is characteristic of the disease.

24 Dec 2015

Novel antibody improves glucose regulation and reduces fatty liver in obese mice

A new study by researchers from Harvard T.H. Chan School of Public Health and colleagues describes the pre-clinical development of a therapeutic that could potentially be used to treat type 2 diabetes, fatty liver disease, and other metabolic diseases.

24 Dec 2015

Eating at the wrong time of day affects learning and memory

An occasional late-night raid on turkey leftovers might be harmless but new research with mice suggests that making a habit of it could alter brain physiology.

24 Dec 2015

Researchers identify 124 protein targets of artemisinin in most pathogenic malaria parasite

A team of researchers from the National University of Singapore (NUS) has uncovered the mystery behind the potent parasite-killing effect of artemisinin, a drug that is considered to be the last line of defence against malaria. Given the emergence of artemisinin resistance, these findings could potentially lead to the design of new treatments against drug-resistant parasites.

24 Dec 2015

NEJM publishes results of Cosentyx Phase III studies in ankylosing spondylitis

Novartis announced today that the results of the MEASURE 1 and MEASURE 2 Phase III studies for Cosentyx® (secukinumab) in ankylosing spondylitis (AS) were published in The New England Journal of Medicine (NEJM). These pivotal studies demonstrated significant clinical improvements with Cosentyx versus placebo in reducing the signs and symptoms of active AS – a long-term, painful and debilitating inflammation of the spine.

24 Dec 2015

IASLC lauds FDA approval of alectinib for lung cancer treatment

The International Association for the Study of Lung Cancer (IASLC) is once again gratified to see the approval of a new second-generation lung cancer treatment that can help many patients in their battle against the disease.

24 Dec 2015

YAP protein appears to play vital role in helping control inflammation inside the brain

Inside the brain, a protein called YAP, best known for its ability to help right-size our developing hearts and livers, appears to have the different but equally important task of helping control inflammation.

23 Dec 2015

Researchers identify underlying molecular mechanism of cardiac hypertrophy

Specific genes are responsible for determining cell growth and differentiation during the early stages of cardiac development. Reactivation of these genes later in life can lead to an abnormal thickening of the heart muscle. Researchers from Charité -- Universitätsmedizin Berlin lead by Professor Silke Rickert-Sperling have been able to identify the underlying molecular mechanism.

23 Dec 2015

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

As we age, proteins in the lenses of our eyes start misbehaving: They unfold and congregate in clusters that block, scatter and distort light as it passes through the lens. A cloudy area, or cataract, forms. In a new study, scientists found that throughout our lifetime, levels of a key protein decline, and may be an early warning sign of a developing cataract.

23 Dec 2015

Researchers identify cause of rare syndrome consistent with Fanconi Anemia

An international team of researchers has established the cause of rare syndrome consistent with Fanconi Anemia: a de novo mutation in a so called RAD51 gene, which is responsible for repairing damages in the DNA.

23 Dec 2015

NUS scientists uncover mystery behind potent parasite-killing effect of artemisinin

A team of researchers from the National University of Singapore has uncovered the mystery behind the potent parasite-killing effect of artemisinin, a drug that is considered to be the last line of defence against malaria. Given the emergence of artemisinin resistance, these findings could potentially lead to the design of new treatments against drug-resistant parasites.

23 Dec 2015

New $8.5M research grant aims to address patients affected by severe hemophilia A

People with hemophilia have prolonged abnormal bleeding as a result of trauma. Hemophilia A, also called factor VIII (FVIII) deficiency, is the most common form of the genetic disorder caused by missing or defective blood clotting protein called factor VIII.

23 Dec 2015

Zinc levels in breast milk may help identify breast-feeding problems

Zinc levels in breast milk may be able to serve as an indicator of breast function during lactation, according to Penn State health researchers.

23 Dec 2015

Researchers awarded $16 million NIH/NINDS grant to create methods for detecting CTE during life

Researchers from Boston University, the Cleveland Clinic, Banner Alzheimer's Institute and Brigham and Women's Hospital in Boston, have been awarded a $16 million grant from the National Institutes of Health/National Institute of Neurological Disorders and Stroke.

23 Dec 2015

Cholesterol essential for health, but also plays key role in longevity

Animals from tiny worms to human beings have a love-hate relationship with fats and lipids. Cholesterol is a famous example of how they are both essential for health and often have a role in death.

23 Dec 2015

Researchers describe epigenetic mechanisms underlying the development of cerebellum

From before birth through childhood, connections form between neurons in the brain, ultimately making us who we are. So far, scientists have gained a relatively good understanding of how neural circuits become established, but they know less about the genetic control at play during this crucial developmental process.

23 Dec 2015

TIGER-X study reviews efficacy of rociletinib therapy in patients with EGFR mutant-positive NSCLC

Oncology & Hematology Review, the peer-reviewed journal, has published a review highlighting recent data around rociletinib, an investigational therapy in patients with previously treated EGFR mutant-positive non-small cell lung cancer.

23 Dec 2015

Inorganic mercury can damage key cell processes, finds UGA study

University of Georgia research has found that inorganic mercury, which was previously thought to be a less harmful form of the toxic metal, is very damaging to key cell processes.

22 Dec 2015

Novoron Bioscience receives NIH grant to study novel therapeutic approach for multiple sclerosis

Novoron Bioscience, Inc., a private biotech company dedicated to developing new therapeutics for disorders of the central nervous system, today announced that the company has been awarded a National Institutes of Health grant under the Small Business Innovation Research (SBIR) Program.

22 Dec 2015

Researchers reveal inherited genetic errors across 12 cancer types

Researchers long have known that some portion of the risk of developing cancer is hereditary and that inherited genetic errors are very important in some tumors but much less so in others.

22 Dec 2015

Protein News and Research

Further Reading

Study directly links common variants of Alzheimer's risk genes to atrophy

Novel antibody improves glucose regulation and reduces fatty liver in obese mice

Eating at the wrong time of day affects learning and memory

Researchers identify 124 protein targets of artemisinin in most pathogenic malaria parasite

NEJM publishes results of Cosentyx Phase III studies in ankylosing spondylitis

IASLC lauds FDA approval of alectinib for lung cancer treatment

YAP protein appears to play vital role in helping control inflammation inside the brain

Researchers identify underlying molecular mechanism of cardiac hypertrophy

Dynamic light scattering technique may help detect people at risk of cataracts and presbyopia

Researchers identify cause of rare syndrome consistent with Fanconi Anemia

NUS scientists uncover mystery behind potent parasite-killing effect of artemisinin

New $8.5M research grant aims to address patients affected by severe hemophilia A

Zinc levels in breast milk may help identify breast-feeding problems

Researchers awarded $16 million NIH/NINDS grant to create methods for detecting CTE during life

Cholesterol essential for health, but also plays key role in longevity

Researchers describe epigenetic mechanisms underlying the development of cerebellum

TIGER-X study reviews efficacy of rociletinib therapy in patients with EGFR mutant-positive NSCLC

Inorganic mercury can damage key cell processes, finds UGA study

Novoron Bioscience receives NIH grant to study novel therapeutic approach for multiple sclerosis

Researchers reveal inherited genetic errors across 12 cancer types

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