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TFAH's new report on flu finds higher hospitalization rates among African Americans

H1N1 flu hospitalization rates for African-Americans, Hispanics, and American Indian/Alaska Natives were nearly two to one higher than rates for Whites during the 2009-2010 flu season, according to a new report, Fighting Flu Fatigue, from the Trust for America's Health (TFAH). At the same time, both H1N1 and seasonal flu vaccination rates were lower for African Americans and Hispanics than for Whites.

11 Nov 2010

New approach to sneak nerve-protective drug erythropoietin into blood-brain barrier

Scientists are reporting development of a long-sought method with the potential for getting medication through a biological barrier that surrounds the brain, where it may limit the brain damage caused by stroke. Their approach for sneaking the nerve-protective drug erythropoietin into the brain is medicine's version of the Trojan Horse ploy straight out of ancient Greek legend.

11 Nov 2010

NJIT expert to discuss history of sickle cell disease at NIH symposium

The history of sickle cell disease in the 20th century and its link to race is the focus of a Nov. 16, 2010 talk at a national symposium by NJIT Associate Professor Stephen Pemberton, PhD, an expert on the history of diseases. Pemberton will speak and join a panel discussion at the National Institutes of Health (NIH), Bethesda, 100th anniversary symposium commemorating the discovery of sickle cell disease by Chicago physician James B. Herrick.

11 Nov 2010

Pleasurable activity also reduces stress by inhibiting anxiety responses

Whether it's food or sex, pleasurable activity provides more than just pleasure, University of Cincinnati (UC) researchers say. It actually reduces stress by inhibiting anxiety responses in the brain.

11 Nov 2010

Neuronal circuits involved in acquisition and control of behavioural fear responses identified

Fear is an adaptive response, essential to the survival of many species. This behavioural adaptation may be innate but can also be a consequence of conditioning, during the course of which an animal learns that a particular stimulus precedes an unpleasant event. There is a large amount of data indicating that the amygdala, a particular structure in the brain, is strongly involved during the learning of "conditioned" fear. However, until now, the underlying neuronal circuits have remained largely unknown.

11 Nov 2010

Incyte presents data on INCB28050 Phase IIa trial for rheumatoid arthritis at ACR/ARHP Meeting

Incyte Corporation announced the presentation of final six-month clinical data from the dose ranging, placebo-controlled Phase IIa trial of its orally available janus kinase (JAK) inhibitor INCB28050 in patients with active rheumatoid arthritis (RA).

11 Nov 2010

Alnylam Pharmaceuticals presents ALN-VSP Phase I data for liver cancer at Chemotherapy Foundation Symposium

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today presented additional interim data from its ongoing Phase I trial with ALN-VSP, a systemically delivered RNAi therapeutic for the treatment of advanced solid tumors with liver involvement. The data were presented at the Chemotherapy Foundation Symposium being held in New York City.

11 Nov 2010

Mother's poor nutrition during pregnancy affects offspring's ability to process medications

New research has found that a mother's poor nutrition during pregnancy and nursing can cause problems for her offspring's ability to process medications, even well into adulthood.

11 Nov 2010

Scientists identify new way to drive dendritic cells from blood monocytes

Dendritic cells, known to be the prime movers of the body's immune response, are still notoriously difficult to study in humans. Samples, which come primarily from bone marrow or lymphoid tissue, are simply too difficult to obtain. But new research at Rockefeller University has shown scientists a way to study "authentic" dendritic cells from mouse monocytes, which are abundant in the blood, a much more accessible source in humans.

11 Nov 2010

Hygeia completes HYG-102 preclinical studies for vulvar and vaginal atrophy, and age-related skin fragility

Hygeia Therapeutics, Inc. announced today the successful completion of a series of preclinical studies for HYG-102, their lead product for the treatment of vulvar and vaginal atrophy (VVA) and age-related skin fragility. HYG-102 is the lead biodegradable estrogenic candidate in a portfolio of 23 similar compounds licensed from the laboratory of Dr. Richard Hochberg of Yale University.

11 Nov 2010

SRU Biosystems announces launch of annual Label-free Technology Award

SRU Biosystems, a leader in label-free technologies, announced today the launch of its annual Label-free Technology Award. This year the company will award its newest label-free BIND SCANNER to an academic or non-profit laboratory to support innovative scientific and drug discovery research.

11 Nov 2010

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Using proton pump inhibitors and antiplatelet drugs (thienopyridines) together is an appropriate way of treating patients with cardiovascular disease who are at high risk of upper gastrointestinal bleeds, despite recent concerns about an adverse interaction between these two types of drugs, according to an Expert Consensus Document released jointly today by the American College of Cardiology Foundation, the American College of Gastroenterology, and the American Heart Association.

10 Nov 2010

Researcher awarded Sylvia and Charles Viertel Charitable Foundation Fellowship

Walter and Eliza Hall Institute researcher Dr Ross Dickins has been awarded a Sylvia and Charles Viertel Charitable Foundation Fellowship worth $AUD975,000 over five years.

10 Nov 2010

UC Davis researchers identify new pathway to repair oxidative-damaged DNA

UC Davis researchers have found a new pathway for repairing DNA damaged by oxygen radicals. The results are published this week in the journal Proceedings of the National Academy of Sciences.

10 Nov 2010

Pres. Obama emphasizes U.S.-Indian partnerships to track, fight diseases

On his final day in India as part of his 10-day Asia-Pacific tour, President Barack Obama on Monday addressed the joint session of the Indian Parliament in New Dehli, where he emphasized the importance of U.S.-Indian partnerships to tackle disease and improve education, Indo-Asian News Service/Hindustan Times reports (11/8).

10 Nov 2010

NCI awards $4 million for UNM's cancer nanotechnology partnership with Sandia Labs

The National Cancer Institute recently announced two five-year awards totaling nearly $4 million for a partnership between the University of New Mexico Cancer Center and Sandia National Laboratories. One $1.95 million grant will fund the creation of a joint Cancer Nanotechnology Platform Partnership, and another $1.8 million grant will pay for a new Cancer Nanotechnology Training Center to train a new generation of multidisciplinary scientists.

10 Nov 2010

Cholera confirmed in Haiti's capital as health ministry says outbreak has killed 544 so far

Haiti's cholera outbreak appears to have spread to its capital, "imperiling nearly 3 million people living in Port-au-Prince, nearly half of them in unsanitary tent camps for the homeless from the Jan. 12 earthquake," the Associated Press/KIRO reports.

10 Nov 2010

Research may help develop new therapies for aggressive prostate cancer

A monoclonal antibody targeting a well known cell surface protein inhibited prostate cancer growth and metastasis in an aggressive form of the disease that did not respond to hormone therapy, according to a study by researchers with the UCLA Department of Urology and UCLA's Jonsson Comprehensive Cancer Center.

9 Nov 2010

Endeca, eHealth Ontario partner to implement chronic disease management system

Endeca Technologies, Inc., a search and business intelligence (BI) company, today announced that eHealth Ontario, an agency of the Government of Ontario, has selected Endeca and commenced work on the chronic disease management system (CDMS) and portal project previously announced in August 2010. Endeca, working with its partners, will assist with the design, build, and implementation of the system that will be used initially to better manage diabetes care throughout the province.

9 Nov 2010

DHA protects brain tissue and promotes recovery in acute ischemic stroke

Research led by Dr. Nicolas Bazan, Boyd Professor, Villere Chair, and Director of the Neuroscience Center of Excellence at LSU Health Sciences Center, has shown that Docosahexaenoic acid (DHA), a component of fish oil, is a powerful therapeutic agent that can protect brain tissue and promote recovery in an experimental model of acute ischemic stroke, even when treatment is delayed by up to five hours.

9 Nov 2010

Laboratory News and Research

TFAH's new report on flu finds higher hospitalization rates among African Americans

New approach to sneak nerve-protective drug erythropoietin into blood-brain barrier

NJIT expert to discuss history of sickle cell disease at NIH symposium

Pleasurable activity also reduces stress by inhibiting anxiety responses

Neuronal circuits involved in acquisition and control of behavioural fear responses identified

Incyte presents data on INCB28050 Phase IIa trial for rheumatoid arthritis at ACR/ARHP Meeting

Alnylam Pharmaceuticals presents ALN-VSP Phase I data for liver cancer at Chemotherapy Foundation Symposium

Mother's poor nutrition during pregnancy affects offspring's ability to process medications

Scientists identify new way to drive dendritic cells from blood monocytes

Hygeia completes HYG-102 preclinical studies for vulvar and vaginal atrophy, and age-related skin fragility

SRU Biosystems announces launch of annual Label-free Technology Award

PPIs, antiplatelet drugs can help treat CV disease patients at high risk of upper GI bleeding

Researcher awarded Sylvia and Charles Viertel Charitable Foundation Fellowship

UC Davis researchers identify new pathway to repair oxidative-damaged DNA

Pres. Obama emphasizes U.S.-Indian partnerships to track, fight diseases

NCI awards $4 million for UNM's cancer nanotechnology partnership with Sandia Labs

Cholera confirmed in Haiti's capital as health ministry says outbreak has killed 544 so far

Research may help develop new therapies for aggressive prostate cancer

Endeca, eHealth Ontario partner to implement chronic disease management system

DHA protects brain tissue and promotes recovery in acute ischemic stroke

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