Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Global Blood Therapeutics, Array BioPharma partner for drug discovery research

Array BioPharma Inc. and Global Blood Therapeutics today announced a multi-target drug discovery collaboration agreement to identify small molecule lead compounds targeting chronic blood-based diseases.

6 Mar 2013

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

UT Southwestern Medical Center scientists report the first successful blocking of tumor development in a genetic mouse model of an incurable human cancer.

6 Mar 2013

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Researchers have identified a critical protein role in the metastasis of melanoma, the most serious form of skin cancer.

6 Mar 2013

Scientists discover key biochemical step underlying heart failure

Some 5.8 million Americans suffer from heart failure, a currently incurable disease. But scientists at Temple University School of Medicine's (TUSM) Center for Translational Medicine have discovered a key biochemical step underlying the condition that could aid the development of new drugs to treat and possibly prevent it.

6 Mar 2013

European scientists find root cause of age-related dementia

A team of European scientists from the University Medical Center Hamburg-Eppendorf and the Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases at the University of Cologne in Germany has taken an important step closer to understanding the root cause of age-related dementia.

6 Mar 2013

Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones

Today, the Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones: the renewal of the partnership agreement for an extended period of 10 years, and the expansion of the Nordic EMBL network with the official opening of the Danish Research Institute of Translational Neuroscience (DANDRITE) at Aarhus University, which will become its Danish node.

6 Mar 2013

Study shows how high shear stress could cause VWF to change shape and form blood clots

New research from Rice University, Baylor College of Medicine (BCM) and the Puget Sound Blood Center (PSBC) has revealed how stresses of flow in the small blood vessels of the heart and brain could cause a common protein to change shape and form dangerous blood clots.

6 Mar 2013

Deleting Plin2 gene prevents obesity in mice

Researchers have discovered that deleting a specific gene in mice prevents them from becoming obese even on a high fat diet, a finding they believe may be replicated in humans.

6 Mar 2013

Insight into how protein synthesis and degradation help regulate delicate ballet of cell division

Biochemists at the University of Massachusetts Amherst including assistant professor Peter Chien recently gained new insight into how protein synthesis and degradation help to regulate the delicate ballet of cell division. In particular, they reveal how two proteins shelter each other in "mutually assured cleanup" to insure that division goes smoothly and safely.

5 Mar 2013

Gene cluster implicated in Behçet's disease

Scientists may have uncovered an underlying genetic susceptibility for Behçet's disease in East Asian patients.

5 Mar 2013

tRNA synthetases play unexpected and critical role in cancer metastasis

Studied for decades for their essential role in making proteins within cells, several amino acids known as tRNA synthetases were recently found to have an unexpected - and critical - additional role in cancer metastasis in a study conducted collaboratively in the labs of Karen Lounsbury, Ph.D., University of Vermont professor of pharmacology, and Christopher Francklyn, Ph.D., UVM professor of biochemistry.

5 Mar 2013

Sanofi, DBV Technologies partner to produce Viaskin's Active Pharmaceutical Ingredients

DBV Technologies, creator of Viaskin, a new standard in the treatment of allergies, announced today that it entered into a strategic manufacturing agreement with Sanofi to produce Viaskin's Active Pharmaceutical Ingredients (API), such as the peanut protein extract.

5 Mar 2013

Five scientists aim to make strides in predicting and preventing preterm birth

Five researchers from four states are investigating how genetics and infections interact to cause preterm birth as well as how proteins and hormones regulate a healthy pregnancy, all with the goal of giving more babies a healthy start in life, the March of Dimes announced today.

5 Mar 2013

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Sanford-Burnham Medical Research Institute and 60- Pharmaceuticals, LLC, have entered into a partnership to test furin, a human proteinase, as a drug target for the treatment of dengue fever, one of the most common infectious diseases in the tropics and subtropics.

5 Mar 2013

Oxidative stress turns protein that protects healthy cells into executioner: Study

Oxidative stress turns a protein that normally protects healthy cells into their executioner, according to a study released today in the Proceedings of the National Academy of Sciences journal.

5 Mar 2013

Carbohydrate-rich diet during pregnancy may predict RSV severity in infants

An important predictor of the severity of respiratory syncytial virus (RSV) in infants may be what their mothers ate during pregnancy, according to a Vanderbilt study published in the American Journal of Respiratory and Critical Care Medicine.

5 Mar 2013

Brain adds new cells during puberty to help navigate complex social world of adulthood

The brain adds new cells during puberty to help navigate the complex social world of adulthood, two Michigan State University neuroscientists report in the current issue of the Proceedings of the National Academy of Sciences.

5 Mar 2013

Biogen announces FDA acceptance of rFIXFc BLA for treatment of hemophilia B

Biogen Idec announced today that the U.S. Food and Drug Administration (FDA) has accepted the company's Biologics License Application (BLA) for the marketing approval of recombinant factor IX Fc fusion protein (rFIXFc) for the treatment of hemophilia B and granted the company a standard review timeline.

5 Mar 2013

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Pfizer Inc. presented today the results from a Phase 3 study demonstrating the immunogenicity, tolerability and safety of Prevnar 13 (Pneumococcal 13-valent Conjugate Vaccine Diphtheria CRM197 Protein)in adults infected with human immunodeficiency virus (HIV).

5 Mar 2013

Researchers discover new candidate disease proteins for neurodegenerative disorders

A multi-institution group of researchers has found new candidate disease proteins for neurodegenerative disorders.

4 Mar 2013

Protein News and Research

Further Reading

Global Blood Therapeutics, Array BioPharma partner for drug discovery research

Scientists report successful blocking of tumor development in genetic mouse model of human cancer

Targeting ARF6 may be effectively prevent melanoma metastasis to lungs

Scientists discover key biochemical step underlying heart failure

European scientists find root cause of age-related dementia

Nordic EMBL Partnership for Molecular Medicine celebrates two important milestones

Study shows how high shear stress could cause VWF to change shape and form blood clots

Deleting Plin2 gene prevents obesity in mice

Insight into how protein synthesis and degradation help regulate delicate ballet of cell division

Gene cluster implicated in Behçet's disease

tRNA synthetases play unexpected and critical role in cancer metastasis

Sanofi, DBV Technologies partner to produce Viaskin's Active Pharmaceutical Ingredients

Five scientists aim to make strides in predicting and preventing preterm birth

Sanford-Burnham enters into partnership to test furin for treatment of dengue fever

Oxidative stress turns protein that protects healthy cells into executioner: Study

Carbohydrate-rich diet during pregnancy may predict RSV severity in infants

Brain adds new cells during puberty to help navigate complex social world of adulthood

Biogen announces FDA acceptance of rFIXFc BLA for treatment of hemophilia B

Results from Pfizer’s Prevnar 13 Phase 3 study on HIV

Researchers discover new candidate disease proteins for neurodegenerative disorders

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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