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High troponin levels after exercise predict risk of cardiovascular events

Regular exercise is healthy and reduces the risk of cardiovascular disease. Nevertheless, it appears that prolonged and/or intensive exercise can lead to an increase in cardiac biomarkers in the blood, such as the regulatory protein troponin. Troponin is a protein that is present in every heart muscle cell.

14 Aug 2019

Removing single enzyme improves outcomes in mouse model of sepsis

Sepsis occurs when the body goes overboard in its attempt to fight off an infection. Immune cells rush in, overreact and wreak havoc on tissues and organs, often resulting in organ failure and death.

14 Aug 2019

Researchers identify molecular switch that impacts immune responses to viral infections

Walter and Eliza Hall Institute researchers have identified a molecular switch that impacts immune responses to viral infections, and whether or not protective antibodies are produced.

14 Aug 2019

Scientists demonstrate an in vitro kidney model

Kidneys work to constantly filter blood and remove toxins from the body. Conditions such as chronic kidney disease are characterized by a reduced ability to perform this essential function.

14 Aug 2019

New automated tool maps the movement of particles inside cells

Scientists have developed an automated tool for mapping the movement of particles inside cells that may accelerate research in many fields, a new study in eLife reports.

14 Aug 2019

Deadly protein combination reveals new drug targets for viral infections

New research from Cornell University details how two highly lethal viruses have greater pathogenic potential when their proteins are combined.

14 Aug 2019

Researchers identify new transmembrane protein as chloride ion channel

In the human body the salt content of cells and their surrounding is regulated by sophisticated transport systems.

14 Aug 2019

Penn State researcher awarded NSF grant to model cell disorder in the heart

On average, the human heart beats anywhere from 60 to 80 times per minute - that's almost 42 million times a year. Each beat consists of billions of cells working together, using their protein channels to pass electrical signals across the muscle.

14 Aug 2019

Roswell Park receives more than $15 million in grants for cancer research

Roswell Park Comprehensive Cancer Center researchers have received more than a dozen recent grant awards totaling more than $15.4 million.

14 Aug 2019

Uchicago Medicine oncologist to receive 2019 Henry M. Stratton Medal for hematology research

For his pioneering hematology research, University of Chicago Medicine oncologist and professor Richard A. Larson, MD, will receive the 2019 Henry M. Stratton Medal from the American Society of Hematology.

13 Aug 2019

Study shows how cervicovaginal microbiome can elicit resistance to chlamydia

The vaginal microbiome is believed to protect women against Chlamydia trachomatis, the etiological agent of the most prevalent sexually transmitted infections in developed countries.

13 Aug 2019

Mice study suggests anti-cancer effect of ketogenic diet

It's well known that keeping blood glucose levels in check can help individuals avoid or manage diabetes, but new research led by biologists at The University of Texas at Dallas suggests that restricting blood glucose levels might also keep certain cancers at bay.

13 Aug 2019

Using cannabis and opioids for pain increases mental health issues

Opioid misuse has become a significant public health problem. Despite efforts to control its use, opioid is still the most widely prescribed class of medicines. Now, a new study shows that when adults mix prescription opioids for pain with marijuana or cannabis, they report higher rates of anxiety and depression symptoms.

13 Aug 2019

Researchers examine how superbug fights last-resort antibiotics

Antibiotic resistance is one of the biggest threats to global health, food security, and development today. A new study shows how superbugs adapt to combat 'last-resort antibiotics'.

13 Aug 2019

Sartorius Stedim Biotech announces launch of new services for mammalian cell bank manufacturing

Sartorius Stedim Biotech (SSB), a leading partner of the biopharmaceutical industry, today announced the launch of new services for mammalian cell bank manufacture under GMP conditions.

From Sartorius 13 Aug 2019

Bile pigment may play an unexpected role in protecting the brain

In studies in mice, Johns Hopkins Medicine researchers report they have found that bilirubin, a bile pigment most commonly known for yellowing the skin of people with jaundice, may play an unexpected role in protecting brain cells from damage from oxidative stress.

From Johns Hopkins Medicine 13 Aug 2019

Newborn mouse model yields clues to cause of devastating gut disease in anemic preemies

Physicians have long suspected that red blood cell transfusions given to premature infants with anemia may put them in danger of developing necrotizing enterocolitis, or NEC, a potentially lethal inflammatory disease of the intestines.

From Johns Hopkins Medicine 13 Aug 2019

Beta amyloid structure mapped in new Alzheimer’s research

In search of a possible cure for Alzheimer’s disease (AD), scientists have found out the molecular structure of a type of protein called beta amyloid that accumulates within brain cells, eventually killing them. This could help understand how to prevent these abnormal proteins from forming, leading to a cure or treatment for this killer disease.

13 Aug 2019

NUS scientists discover control mechanism that regulates traffic across blood vessels

NUS scientists have discovered a control mechanism that regulates the traffic of cells and substances across blood vessels. This effect can have significant impact on cancer metastasis.

13 Aug 2019

Neuronal gene mutations may be linked to seizures associated with Long QT Syndrome

Researchers identified a gene in fruit flies that helps prevent the hyperexcitability of specific neurons that trigger seizures. In humans, mutations in the gene may be linked to seizures associated with Long QT Syndrome.

From PLOS ONE 13 Aug 2019