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Chronic insomnia with objectively measured short sleep duration associated with increased mortality in men

A study in the Sept. 1 issue of the journal SLEEP found an elevated risk of death in men with a complaint of chronic insomnia and an objectively measured short sleep duration. The results suggest that public health policy should emphasize the diagnosis and appropriate treatment of chronic insomnia.

2 Sep 2010

Mipomersen Phase 3 trial in heFH meets primary, secondary and tertiary endpoints

Genzyme Corp. and Isis Pharmaceuticals Inc. announced that data from the phase 3 study of mipomersen in patients with heterozygous familial hypercholesterolemia (heFH) were presented today at the European Society of Cardiology's Congress 2010 in Stockholm, Sweden. The study met its primary endpoint with a 28 percent reduction in LDL-cholesterol, compared with an increase of 5 percent for placebo (p<0.001). The trial also met all of its secondary and tertiary endpoints.

2 Sep 2010

Inhibitex completes INX-189 Phase1a trial for HCV

Inhibitex, Inc., announced today that it has successfully completed a Phase1a, first-in-man, single ascending dose trial of INX-189, its nucleotide polymerase inhibitor in development for the treatment of chronic hepatitis C (HCV) infections. In this trial, 42 healthy volunteers received either a single oral dose of INX-189, ranging from 3 mg to 100 mg, or placebo. The Company plans to present detailed results from this trial during a future scientific meeting.

2 Sep 2010

Asuragen launches KRAS, BRAF mutational testing in CLIA laboratory

Asuragen, Inc., a leader in molecular diagnostics and nucleic acid-based pharmacogenomics services, announced today that it has launched KRAS and BRAF mutational testing services in its CAP-accredited CLIA laboratory.

2 Sep 2010

Celator Pharmaceuticals raises $20 million in Series D private equity financing

Celator Pharmaceuticals, a privately held pharmaceutical company developing new and more effective therapies to treat cancer based on the company's proprietary technology, today announced that it raised $20 million in a Series D private equity financing.

2 Sep 2010

Abbott RealTime HBV assay receives marketing approval from FDA

Abbott announced today it has received approval from the U.S. Food and Drug Administration to market the Abbott RealTime HBV assay for measuring viral load or the amount of hepatitis B virus in a patient's blood. It is the first and only approved test capable of automating HBV viral load testing from sample extraction to final results.

2 Sep 2010

Neutralizing key toxin associated with Staph aureus bacteria reduces severity of skin and soft-tissue damage

Scientists from the National Institutes of Health and University of Chicago have found a promising treatment method that in laboratory mice reduces the severity of skin and soft-tissue damage caused by USA300, the leading cause of community-associated Staphylococcus aureus infections in the United States.

2 Sep 2010

New research clinic in Edinburgh to improve outcomes for multiple sclerosis sufferers

A research clinic for multiple sclerosis patients is being set up with a -10 million donation from the author J K Rowling.The Anne Rowling Regenerative Neurology Clinic at the University of Edinburgh will place patients at the heart of research to improve outcomes for multiple sclerosis sufferers.

2 Sep 2010

First mind controlled prosthesis

Christian Kandlbauer, who lost both of his arms in a high voltage accident, uses a unique development which until recently sounded almost like science fiction: An arm prosthesis, the first of its kind in the world, which he controls solely through the power of his mind.

31 Aug 2010

Scientists find effective training regimens to determine exercise intensity

For competitive bicyclists with goals - whether competing in the Tour de France or aiming for the podium at a local race - faster cycling comes from training regimens based on various zones of exercise intensity. New research from exercise scientists at the University of New Hampshire has found that effective training regimens, which generally are created after expensive, time-consuming laboratory tests, can be developed from a relatively simple, do-it-yourself test.

31 Aug 2010

Older people prefer to read negative news about young adults: Study

When given a choice, older people prefer to read negative news, rather than positive news, about young adults, a new study suggests.

31 Aug 2010

ANTIPAF trial reveals ARBs do not reduce number of AF episodes in paroxysmal AF patients

Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting about 7 million people in Europe. It is a progressive chronic disease in which episodes become more frequent and long-lasting over time. Conventional anti-arrhythmic therapy aims at halting progression and reducing symptoms, but the use of most anti-arrhythmic drugs is compromised by severe side effects, such as pro-arrhythmia or extra-cardiac organ toxicity.

31 Aug 2010

Bioheart's MyoCell adult stem cell therapy shows effective for heart failure patients: Study

Bioheart, Inc., The mission of the Cell Therapy Foundation is to improve public health through the support of effective adult stem cell research and education. The Foundation aims to promote basic and applied knowledge, processes and cell therapies.

31 Aug 2010

MGH scientists develop new microfluidic tool for accurate isolation of neutrophils

A team led by Massachusetts General Hospital (MGH) scientists has developed a new microfluidic tool for quickly and accurately isolating neutrophils - the most abundant type of white blood cell - from small blood samples, an accomplishment that could provide information essential to better understanding the immune system's response to traumatic injury. The system, described in a Nature Medicine paper that received advance online release, also can be adapted to isolate almost any type of cell.

31 Aug 2010

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

New research on how skin cancer begins has identified adjacent cancer cells that scientists are calling "co-conspirators" in the genesis of melanoma, in findings that could someday hold the key to predicting, preventing and stopping this hard-to-treat cancer before it spreads.

31 Aug 2010

Amino acid arginine vital in fighting infection

Richard Lamb and his post doctoral fellow Virginie Mieulet, in the Faculty of Medicine & Dentistry, may be able to explain why proper nutrition is so vital in fighting infection.

31 Aug 2010

Cell Therapy Foundation analysis calls for funding in medical research

Some of the most promising medical research conducted to treat diseases of the brain, heart, and circulatory system is moving too slowly to help millions of patients, according to the Cell Therapy Foundation, which advocates the use of adult stem cells to dramatically impact and improve the condition of patients who suffer from a variety of conditions.

31 Aug 2010

Valley Presbyterian Hospital wins 'Best Hospital' designation for fifth consecutive year

Valley Presbyterian Hospital (VPH) has won the "Best Hospital" designation for the fifth consecutive year in a poll of Los Angeles Daily News readers. The annual Readers' Choice online survey was conducted independently by the Los Angeles Daily News.

31 Aug 2010

Cognizant Communication launches 'Cell Medicine' open access journal

A new and unique journal on cell transplantation aimed at helping translate laboratory findings into clinical applications is being launched by Cognizant Communication Corporation as a companion journal to Cell Transplantation. Cell Medicine, an online-only, open access journal, publishes research papers that promise to have direct clinical relevance. The journal is freely accessible at: http://www.ingentaconnect.com/content/cog/cm.

30 Aug 2010

SQI Diagnostics 2010 third quarter net loss increases to $1,613K

SQI Diagnostics Inc.,a medical systems automation company focused on evolving laboratory-based biomarker testing, today announced its financial and operational results for the third quarter ended June 30, 2010.

30 Aug 2010

Laboratory News and Research

Chronic insomnia with objectively measured short sleep duration associated with increased mortality in men

Mipomersen Phase 3 trial in heFH meets primary, secondary and tertiary endpoints

Inhibitex completes INX-189 Phase1a trial for HCV

Asuragen launches KRAS, BRAF mutational testing in CLIA laboratory

Celator Pharmaceuticals raises $20 million in Series D private equity financing

Abbott RealTime HBV assay receives marketing approval from FDA

Neutralizing key toxin associated with Staph aureus bacteria reduces severity of skin and soft-tissue damage

New research clinic in Edinburgh to improve outcomes for multiple sclerosis sufferers

First mind controlled prosthesis

Scientists find effective training regimens to determine exercise intensity

Older people prefer to read negative news about young adults: Study

ANTIPAF trial reveals ARBs do not reduce number of AF episodes in paroxysmal AF patients

Bioheart's MyoCell adult stem cell therapy shows effective for heart failure patients: Study

MGH scientists develop new microfluidic tool for accurate isolation of neutrophils

RXR-alpha protein helps to protect pigment cells from invasive melanoma: Research

Amino acid arginine vital in fighting infection

Cell Therapy Foundation analysis calls for funding in medical research

Valley Presbyterian Hospital wins 'Best Hospital' designation for fifth consecutive year

Cognizant Communication launches 'Cell Medicine' open access journal

SQI Diagnostics 2010 third quarter net loss increases to $1,613K

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