Laboratory News and Research

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Study finds abnormal expression of miRNAs can contribute to human diseases

Researchers at Tufts University School of Medicine and Tufts Medical Center have identified an RNA sequence that promotes increased numbers of specific microRNAs (miRNAs), molecules that regulate cell growth, development, and stress response. The discovery helps researchers understand the links between miRNA expression and disease, including heart disease and cancer. The findings are published in the August 13 issue of Molecular Cell.

17 Aug 2010

Ozone, nicotine reaction may become threat to asthma sufferers: Study

Another reason for including asthma on the list of potential health risks posed by secondhand tobacco smoke, especially for non-smokers, has been uncovered. Furthermore, the practice of using ozone to remove the smell of tobacco smoke from indoor environments, including hotel rooms and the interiors of vehicles, is probably a bad idea.

17 Aug 2010

Emisphere second-quarter net loss increases to $13.7 million

Emisphere Technologies, Inc. today announced financial and operational results for the three and six months ended June 30, 2010.

16 Aug 2010

Alverix and BD partner to develop point of care infectious disease diagnostic assay systems

As consumers begin to take greater ownership of their own healthcare, there is a growing demand for accessibility to diagnostic testing. Alverix, Inc. and BD (Becton, Dickinson and Company) are on the cutting edge of this trend and today announced an agreement to produce assay systems at the point-of-care (POC) that will improve infectious disease diagnoses.

From BD (Becton, Dickinson and Company) 16 Aug 2010

NanoViricides' anti-Herpes drug candidates demonstrate significant efficacy in cell culture studies

NanoViricides, Inc., reports that its anti-Herpes drug candidates demonstrated significant efficacy in the recently completed cell culture studies. The studies were performed in the laboratory of Dr. Ken Rosenthal at Northeastern Ohio Universities Colleges of Medicine and Pharmacy.

16 Aug 2010

Researchers develop method to predict lifetime of implants

Extra-hard coatings made from diamond-like carbon (DLC) extend the operating lifetime of tools and components. In artificial joints, however, these coatings often fail because they detach. Empa researchers found out why - and developed methods to both make the interface between the DLC layer and the metal underneath corrosion-resistant and to predict the lifetime of the implants.

16 Aug 2010

Sinovac Biotech second-quarter 2010 sales increase 131% to $10.3 million

Sinovac Biotech Ltd., a leading China-based vaccine manufacturer, announced today its unaudited financial results for the three-month and six-month periods ended June 30, 2010.

16 Aug 2010

Adeona reports $979,782 net income for second-quarter 2010 vs. $879,550 net loss for same period in 2009

Adeona Pharmaceuticals, Inc. announced its second quarter 2010 financial results and recent achievements.

16 Aug 2010

Scientists use PCT technique to understand physical effects of compression on macromolecules

Scientists are turning to a decades-old technique to better understand the physical effects of compression on macromolecules and how it might impact their research in proteomics, mass spectrometry, protein extraction, and tissue investigations, reports Genetic Engineering & Biotechnology News.

16 Aug 2010

Scientists replace human gene to preserve photoreceptor function in retinal degeneration

The easy accessibility of the eye and the established link between specific genetic defects and ocular disorders offer hope for using gene therapy to provide long-term therapeutic benefit. Two reports in the current issue of Human Gene Therapy, a peer-reviewed journal published by Mary Ann Liebert, Inc., describe the effective replacement of a human gene to preserve photoreceptor function in a mouse model of severe retinal degeneration. The articles are available free online.

16 Aug 2010

Low socioeconomic status, stressful childhood events develop risk of cardiovascular disease

Early life adversity through poverty, social isolation or abuse in childhood is linked to heightened reactivity, which can lead to heart disease later on, a leading expert on stress and disease said Saturday."Many diseases first diagnosed in mid-life can be traced back to childhood," Karen A. Matthews, PhD, said at the 118th Annual Convention of the American Psychological Association. "Having some bad health habits in your 20s and 30s is part of the reason why people get diseases later on. However, it isn't the whole reason. The evidence shows that certain reactions to adverse childhood experiences associated with lower socioeconomic status, isolation and negative events can affect the disease process."

16 Aug 2010

Obesity linked to sleep disorders: Study

Specialists at a sleep clinic in Newcastle, Australia have analyzed 20 years of patient’s records and found that their patients are becoming increasingly obese. This means that the rise in obesity rates is directly related to rise in sleep problems they say.

16 Aug 2010

Legal scholar calls for FDA to regulate all health-related genetic tests

An opinion piece by a legal scholar from the Johns Hopkins Berman Institute of Bioethics in this week's issue of Nature calls for the Food and Drug Administration to regulate all health-related genetic tests — whether available directly to consumers or through a health care provider — using an approach that imposes requirements proportionate to a test's level of risk.

13 Aug 2010

U.S. FDA purchases more licenses to Simulations Plus' DDDPlus software

Simulations Plus, Inc., a leading provider of software for pharmaceutical discovery and development, today announced that it has received a purchase order from the U.S. Food and Drug Administration to expand the number of licenses for the Company's DDDPlus™ simulation software.

13 Aug 2010

LabCorp announces collaboration between Esoterix Clinical Trials Services, Clearstone Central Laboratories

Laboratory Corporation of America Holdings announced today a collaboration between Esoterix Clinical Trials Services, a division of LabCorp, and Clearstone Central Laboratories, a global central laboratory specializing in drug development and pharmaceutical services.

13 Aug 2010

Combination of fungi, insecticides can combat malaria mosquitoes: Research

A combination of fungal spores and chemical insecticides are an effective way of combating insecticide-resistant malaria mosquitoes. Researchers at Wageningen UR and from Benin, West Africa, have shown that fungi and insecticides reinforce each other´s efficacy, and that the effect of using a combination of both is greater than the sum of using the two methods separately. Their article in the August edition of PLoS One (Public Library of Science) claims that biological and chemical methods of fighting malaria can and should be used together.

13 Aug 2010

American CareSource second-quarter revenues decrease to $16.0 million

American CareSource Holdings Inc. today announced second quarter 2010 revenues of $16.0 million compared to $17.1 million in the corresponding prior year quarter. Net income for the second quarter 2010 was $299,000, or $0.02 per diluted share, compared to $534,000, or $0.01 per diluted share, in the corresponding prior year quarter. Net income for the second quarter 2010 included a federal income tax provision of $137,000, or $0.01 per diluted share, which was not included in net income for the second quarter 2009.

13 Aug 2010

A*STAR's Singapore Immunology Network, Institut M-rieux and bioM-rieux partner in TB research

An investment of S$3 million is being pumped into tuberculosis (TB) research by A*STAR's Singapore Immunology Network (SIgN), bioindustrial group Institut M-rieux and its in vitro diagnostics company bioM-rieux. The project, which involves setting up a joint laboratory in Biopolis, Singapore aims to investigate and identify novel biomarkers that could allow early identification of individuals at risk of TB disease development and disease reactivation. This could lead to better diagnosis and treatment for the highly contagious disease.

13 Aug 2010

Guided Therapeutics second-quarter service revenue increases to $0.8 million

Guided Therapeutics, Inc. today announced its operating results for the second quarter and first six months of 2010.

13 Aug 2010

U-M dentistry agrees to use Interleukin's PST test for gum disease clinical study

University of Michigan School of Dentistry has signed an agreement with Interleukin Genetics Inc. to conduct what may be the largest clinical study to date using genetic testing to assess the risk for gum disease.

13 Aug 2010

Laboratory News and Research

Study finds abnormal expression of miRNAs can contribute to human diseases

Ozone, nicotine reaction may become threat to asthma sufferers: Study

Emisphere second-quarter net loss increases to $13.7 million

Alverix and BD partner to develop point of care infectious disease diagnostic assay systems

NanoViricides' anti-Herpes drug candidates demonstrate significant efficacy in cell culture studies

Researchers develop method to predict lifetime of implants

Sinovac Biotech second-quarter 2010 sales increase 131% to $10.3 million

Adeona reports $979,782 net income for second-quarter 2010 vs. $879,550 net loss for same period in 2009

Scientists use PCT technique to understand physical effects of compression on macromolecules

Scientists replace human gene to preserve photoreceptor function in retinal degeneration

Low socioeconomic status, stressful childhood events develop risk of cardiovascular disease

Obesity linked to sleep disorders: Study

Legal scholar calls for FDA to regulate all health-related genetic tests

U.S. FDA purchases more licenses to Simulations Plus' DDDPlus software

LabCorp announces collaboration between Esoterix Clinical Trials Services, Clearstone Central Laboratories

Combination of fungi, insecticides can combat malaria mosquitoes: Research

American CareSource second-quarter revenues decrease to $16.0 million

A*STAR's Singapore Immunology Network, Institut M-rieux and bioM-rieux partner in TB research

Guided Therapeutics second-quarter service revenue increases to $0.8 million

U-M dentistry agrees to use Interleukin's PST test for gum disease clinical study

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