Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Wichita State professor hopes to understand how cancer cells spread and become fatal

Through her research at Wichita State University, assistant chemistry professor Moriah Beck hopes to understand how cancer cells spread and become fatal.

30 Nov 2012

Neuro-inflammation plays a crucial role in initiating prion disease

In a recent publication, researchers of the Computational Biology group at the Luxembourg Centre for Systems Biomedicine showed that neuro-inflammation plays a crucial role in initiating prion disease.

30 Nov 2012

Cleveland Clinic researcher names American Association for the Advancement of Science Fellow

Cleveland Clinic researcher Jun Qin, Ph.D., has been named a Fellow of the American Association for the Advancement of Science (AAAS). As part of the Molecular Cardiology Department in the Lerner Research Institute, Qin was elected as an AAAS Fellow for exemplary contributions to the field of cell signaling.

30 Nov 2012

German Research Foundation to establish new CRC at Mainz University Medical Center

On January 1, 2013, the German Research Foundation (DFG) will establish a new Collaborative Research Center (CRC) at the University Medical Center of Johannes Gutenberg University Mainz (JGU).

30 Nov 2012

African Americans experience faster progression of CKD during later stages

Among individuals with chronic kidney disease (CKD), African Americans experience faster progression of the disease during later stages compared with other races, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

30 Nov 2012

Novel SIRT2 inhibitor protects against neuronal damage in animal models of Huntington's

Treatment with a novel agent that inhibits the activity of SIRT2, an enzyme that regulates many important cellular functions, reduced neurological damage, slowed the loss of motor function and extended survival in two animal models of Huntington's disease.

30 Nov 2012

Scientists define key underlying process implicated in multiple sclerosis

Scientists at the Gladstone Institutes have defined for the first time a key underlying process implicated in multiple sclerosis (MS)-a disease that causes progressive and irreversible damage to nerve cells in the brain and spinal cord. This discovery offers new hope for the millions who suffer from this debilitating disease for which there is no cure.

30 Nov 2012

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Epizyme, Inc., a biopharmaceutical company leading the creation of personalized therapeutics to treat patients with genetically defined cancers, today announced the presentation of data evaluating the preclinical safety and efficacy of two of the Company's novel, potent and selective small molecule inhibitors. These inhibitors individually target DOT1L and EZH2, members of a class of epigenic enzymes called histone methyltransferases (HMTs).

30 Nov 2012

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

A three-month-old Winnipeg girl has become the first patient in Canada to receive an experimental and potentially life-saving form of therapy to improve the function of her liver.

29 Nov 2012

ArmaGen closes $17M Series A financing

ArmaGen Technologies, Inc. today announced the closing of a $17 million Series A financing to support the development of brain-penetrating recombinant protein therapeutics.

29 Nov 2012

Methodist dietitian offers tips to prevent holiday weight gain

The holiday season is officially in full gear and with it comes the tempting Thanksgiving-to-New-Year's food fest. While research shows that the average person really only gains about a pound over the course of the holidays, it can still have a big cumulative effect on waistlines. That's because the extra weight usually doesn't come off the following year.

29 Nov 2012

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia

A previously invincible mutation in chronic myeloid leukemia (CML) has been thwarted by an investigational drug in a phase I clinical trial reported in the current edition of The New England Journal of Medicine.

29 Nov 2012

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

As part of their ongoing research on the role of genes in the development of type 1 diabetes, Joslin Diabetes Center scientists, in collaboration with scientists at the University of Würzburg, have demonstrated how a genetic variant associated with type 1 diabetes and other autoimmune diseases influences susceptibility to autoimmunity. The findings appear in the upcoming issue of Diabetes.

29 Nov 2012

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Scientists from the Florida campus of The Scripps Research Institute (TSRI) have uncovered a group of what have been considered relatively minor regulators in the body that band together to suppress the spread of cancer from its primary site.

29 Nov 2012

Microglia might play a key role in protecting brain from Alzheimer's

A new experimental study carried out in mice shows that microglia, immune cells of the brain, might play a key role in protecting the brain from Alzheimer's disease (AD).

29 Nov 2012

Tufts University researchers demonstrate silk-based implantable optics

Tufts University School of Engineering researchers have demonstrated silk-based implantable optics that offer significant improvement in tissue imaging while simultaneously enabling photo thermal therapy, administering drugs and monitoring drug delivery. The devices also lend themselves to a variety of other biomedical functions.

29 Nov 2012

New paper describes MCUR1 protein and its function

Most healthy cells rely on a complicated process to produce the fuel ATP. Knowing how ATP is produced by the cell's energy storehouse - the mitochondria -- is important for understanding a cell's normal state, as well as what happens when things go wrong, for example in cancer, cardiovascular disease, neurodegeneration, and many rare disorders of the mitochondria.

29 Nov 2012

microRNA-223 molecule plays a surprising role in protecting brain cells from stroke effects

A small molecule known to regulate white blood cells has a surprising second role in protecting brain cells from the deleterious effects of stroke, Johns Hopkins researchers report. The molecule, microRNA-223, affects how cells respond to the temporary loss of blood supply brought on by stroke - and thus the cells' likelihood of suffering permanent damage.

29 Nov 2012

Tadalafil may offer therapeutic strategy in patients with Becker muscular dystrophy

Cedars-Sinai Heart Institute researchers have found in an initial clinical trial that a drug typically prescribed for erectile dysfunction or pulmonary hypertension restores blood flow to oxygen-starved muscles in patients with a type of muscular dystrophy that affects males, typically starting in childhood or adolescence.

29 Nov 2012

IL17RC-mediated immune responses can be crucial in causing AMD

Changes in how genes in the immune system function may result in age-related macular degeneration (AMD), the leading cause of visual impairment in older adults, based on preliminary research conducted by National Institutes of Health (NIH) investigators.

29 Nov 2012

Protein News and Research

Further Reading

Wichita State professor hopes to understand how cancer cells spread and become fatal

Neuro-inflammation plays a crucial role in initiating prion disease

Cleveland Clinic researcher names American Association for the Advancement of Science Fellow

German Research Foundation to establish new CRC at Mainz University Medical Center

African Americans experience faster progression of CKD during later stages

Novel SIRT2 inhibitor protects against neuronal damage in animal models of Huntington's

Scientists define key underlying process implicated in multiple sclerosis

Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting

Alberta Children's Hospital performs first liver cell transplant in Calgary, Canada

ArmaGen closes $17M Series A financing

Methodist dietitian offers tips to prevent holiday weight gain

Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia

Study shows how PTPN22 variant linked with T1D influences susceptibility to autoimmunity

DLKI-DIO3 miRNA cluster suppresses spread of cancer from its primary site

Microglia might play a key role in protecting brain from Alzheimer's

Tufts University researchers demonstrate silk-based implantable optics

New paper describes MCUR1 protein and its function

microRNA-223 molecule plays a surprising role in protecting brain cells from stroke effects

Tadalafil may offer therapeutic strategy in patients with Becker muscular dystrophy

IL17RC-mediated immune responses can be crucial in causing AMD

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