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Study shows how fly's circadian clock network takes temperature cues to control sleep

Circuits in the brain act as an internal clock to tell us it is time to sleep and to control how long we then stay asleep. A new study in flies suggests a part of that clock constantly monitors changes in external temperature and integrates that information into the neural network controlling sleep.

8 Mar 2018

UCLA researchers use fluorescent colored proteins to trace origin of heart cells

UCLA researchers used fluorescent colored proteins to trace how cardiomyocytes -- cells in heart muscle that enable it to pump blood -- are produced in mouse embryos. The findings could eventually lead to methods for regenerating heart tissue in human adults.

22 Feb 2018

Scientists successfully produce functioning human kidney tissue

Scientists have successfully produced human kidney tissue within a living organism which is able to produce urine, a first for medical science.

9 Feb 2018

Free magnesium ions regulate chromosome shape, new tool shows

Japanese researchers report a new ion detector, MARIO. Using it, they show that changes in the intracellular concentration of free magnesium ions (Mg2+) is critical for the chromosome folding that must occur for cells to divide.

1 Feb 2018

Economical Fluorescence Adapter for Stereo Microscopes

An interview with Charles Mazel, President of NIGHTSEA, conducted by Barbara Foster, The Microscopy & Imaging Place, Inc.

From NIGHTSEA 25 Jan 2018

Caltech researchers develop new method to see neural connections in living flies

The human brain is composed of billions of neurons wired together in intricate webs and communicating through electrical pulses and chemical signals.

12 Jan 2018

Penn researchers reveal new approach to restart replication in cardiomyocytes after heart attack

In mammals, including humans, the cells that contract the heart muscle and enable it to beat do not regenerate after injury.

29 Nov 2017

New microscope optimized to perform studies using optogenetic techniques

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication.

29 Nov 2017

Researchers uncover how rogue immune cells gain access to neurons in multiple sclerosis

Drug designers working on therapeutics against multiple sclerosis should focus on blocking two distinct ways rogue immune cells attack healthy neurons, according to a new study in the journal Cell Reports.

21 Nov 2017

Scientists invent new way of folding and protecting recombinant proteins

A team from the NUS Yong Loo Lin School of Medicine has invented a fundamentally new way of folding and protecting recombinant proteins.

13 Nov 2017

Antiviral drug selectively targets the most aggressive viruses, research says

An antiviral drug that inhibits a virus' replication machinery selectively targets the most aggressive viruses, according to new research that looked at the infection of individual cells by a virus and the consequence of antiviral intervention.

9 Nov 2017

Stem cells do not participate directly in cartilage regeneration but serve to ‘animate’ the process

Stem cell therapy has great potential for curing cartilage damage. However, it has remained unclear whether stem cells are responsible for regeneration or whether they trigger the process.

31 Oct 2017

Researchers identify link between circadian rhythm disturbance and brain dysfunction

Researchers at Okayama University describe in the Journal of Neuroscience that a certain protein known to play a major role in circadian rhythmicity — humans’ intrinsic 24-hour biological cycle — is also key to proper brain functioning.

31 Oct 2017

CUMC researchers discover ‘cell of origin’ for esophageal cancer

Columbia University Medical Center researchers have identified cells in the upper digestive tract that can give rise to Barrett's esophagus, a precursor to esophageal cancer. The discovery of this "cell of origin" promises to accelerate the development of more precise screening tools and therapies for Barrett's esophagus and esophageal adenocarcinoma, the fastest growing form of cancer in the U.S.

11 Oct 2017

Researchers develop fluorescent sensors for detecting, tracking GTP levels in living cells

For several decades, scientists have recognized the key role that a molecule known as GTP, one of the building blocks of RNA, plays in the development of cancer and other diseases.

13 Sep 2017

UAlberta chemistry professor develops revolutionary neuroscience tools

UAlberta chemistry professor Robert Campbell is developing new ways to see and manipulate the activity of neurons in the brain, which could revolutionize the way we understand the organ that controls most of the activities of the body.

11 Sep 2017

G:BOX Chemi XX6 imaging system used to analyze how bacteria react to stressors

Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its G:BOX Chemi XX6 multi-application imager is being utilized by scientists at the University of Warwick to rapidly and accurately analyze how Gram positive bacteria react to stressors.

From Syngene 8 Sep 2017

Seeing the full picture, real-time analysis of live-cells

Every cell is a miniature factory taking in raw material (extracellular signals) and processing it to produce something (a biological response). But unlike a factory that can be easily tweaked to run at steady-state and look the same from day to day, cells are dynamic.

From Sartorius 7 Sep 2017

Researchers explore causal link between perirhinal neurons and mnemonic judgment of objects

Cognitive neuroscience research on non-human primates demonstrated that judgments of whether humans have previously seen or not seen an object are causally determined by neuronal signals generated in the temporal cortex of the brain. The findings are published in Science (August 2017).

1 Sep 2017

Scientists succeed in teaching robots to perform challenging brain technique

Whole-cell patch clamp electrophysiology, or whole-cell recording (WCR), is the gold-standard technique for studying the behaviour of brain cells called neurons under different brain states such as stress or learning.

31 Aug 2017