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Diabetic nerve damage weakens bones by disrupting cell communication

Diabetes affects millions worldwide, causing both nerve and metabolic complications. A recent study suggests that diabetic nerve damage may also lead to impaired bone health.

18 Jul 2025

ANXA2 positive hepatocytes drive migration based repair in acute liver failure

Acute liver failure (ALF) represents a life-threatening condition marked by rapid deterioration of liver function, often necessitating urgent liver transplantation.

18 Jul 2025

Study reveals how aging alters liver function and structure

The aging liver undergoes dramatic changes in its functional organization and other key attributes, which may underpin its increasing susceptibility to disease, according to a study led by investigators at Weill Cornell Medicine.

17 Jul 2025

Galectin-3 identified as key driver of chemoresistance in pancreatic cancer

Pancreatic cancer is often diagnosed at an advanced stage and is characterized by a poor prognosis and rising mortality.

17 Jul 2025

Fruit fly study sheds light on how new genes become functional

Most genes are ancient and shared across species. But a small subset of genes are relative newcomers, spontaneously emerging from stretches of DNA that once encoded nothing at all.

14 Jul 2025

Viome and Scripps Research join forces to develop at-home RNA test for colon cancer prevention

Viome Life Sciences, the leader in AI-powered, RNA-based diagnostics and precision nutrition and Scripps Research, the leader in accelerating the impact of fundamental research on human health, today announced a strategic partnership to develop and clinically validate the first at-home RNA test designed to detect precancerous colon polyps, enabling early prevention of colorectal cancer.

14 Jul 2025

Shen-Bai-Jie-Du decoction inhibits colorectal tumorigenesis by targeting immunosuppressive dendritic cells

This new article publication from Acta Pharmaceutica Sinica B, discusses how single-cell RNA sequencing reveals that Shen-Bai-Jie-Du decoction retards colorectal tumorigenesis by regulating the TMEM131-TNF signaling pathway-mediated differentiation of immunosuppressive dendritic cells.

12 Jul 2025

Weight loss wipes out senescent fat cells but leaves immune scars, study finds

Researchers have mapped human fat tissue at single-cell resolution, uncovering how obesity alters cellular stress, inflammation, and tissue structure. Weight loss reverses much of this damage, especially senescence in fat and vascular cells, but leaves some immune dysfunction behind.

10 Jul 2025

Could serotonin supplements become the next hair loss treatment?

Researchers have shown that serotonin directly stimulates dermal papilla cells and promotes hair growth in lab-grown hair follicloids and human hair follicles. The findings suggest serotonin and related compounds could offer new avenues for treating hair loss, though safety and dosing challenges remain.

9 Jul 2025

Study identifies why some prostate cancers fail to respond to treatment

A new study from University of Michigan Rogel Cancer Center researchers identifies a cellular signature that explains why about one-third of prostate cancers respond especially poorly to treatment.

8 Jul 2025

Oral lysozyme can restore healthy gut balance and reverse signs of vascular aging

A study reveals that lysozyme (LYZ) plays a pivotal role in age-related blood vessel inflammation by influencing gut bacteria.

8 Jul 2025

Study provides a molecular snapshot of Tanshi constitution's immunological landscape

The study aims to uncover the immunological basis of Tanshi (phlegm-dampness) constitution—a subhealth type in traditional Chinese medicine (TCM)—using single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs).

7 Jul 2025

New neurons form in the hippocampus even in late adulthood

A study in the journal Science presents compelling new evidence that neurons in the brain's memory centre, the hippocampus, continue to form well into late adulthood.

4 Jul 2025

Blocking key immune cells could make prostate cancer treatable

Scientists have revealed how certain immune cells may be quietly helping prostate cancer grow - and how blocking them could help the body fight back.

3 Jul 2025

Single-cell transcriptomes of immune cells offer insight into juvenile idiopathic arthritis

Juvenile idiopathic arthritis (JIA), a type of arthritis commonly occurring in children, is a chronic, inflammatory condition that affects the joints, causing pain, swelling, stiffness, and limiting the range of motion.

2 Jul 2025

Rarely studied RNA linked to triple-negative breast cancer

Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it's also one of the most curable.

1 Jul 2025

Study explores how a familiar spice tackles the toughest cancer cells

Researchers found that clinically achievable doses of curcumin, the active compound in turmeric, target and suppress colorectal cancer stem-like cells, especially in early adenomas. Curcumin shifts these cells toward differentiation, delays tumor growth in mice, and may offer a safe preventive strategy.

27 Jun 2025

Epigenetic enzyme SETD1B drives aggressive growth in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive cancer affecting the blood and bone marrow that progresses rapidly, making immediate treatment essential.

26 Jun 2025

Parse Biosciences GigaLab to support Mount Sinai researchers in generating one of the largest Alzheimer's and Parkinson's single cell datasets

Parse Biosciences today announced their commitment to support researchers from the Icahn School of Medicine at Mount Sinai in generating one of the largest single cell datasets focused on understanding alternative splicing events in the cells of Alzheimer's and Parkinson's patients.

From Parse Biosciences 26 Jun 2025