Bone Marrow News and Research

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Bone Marrow is the soft, sponge-like tissue in the center of most bones. It produces white blood cells, red blood cells, and platelets.

Excess fat in liver, muscle tissue and blood may increase risk of bone loss

Excess fat around the belly has recently been identified as a risk factor for bone loss. Now, a new study has determined that excess liver and muscle fat also may be detrimental to bone.

16 Jul 2013

New noninvasive technique for tracking stem cells after transplantation

A new, noninvasive technique for tracking stem cells after transplantation - developed by a cross-disciplinary team of radiologists, chemists, statisticians and materials scientists at the Stanford University School of Medicine - could help surgeons determine whether a procedure to repair injured or worn-out knees is successful.

12 Jul 2013

Nerves play critical role in development and spread of prostate tumors, say researchers

Researchers at Albert Einstein College of Medicine of Yeshiva University have found that nerves play a critical role in both the development and spread of prostate tumors. Their findings, using both a mouse model and human prostate tissue, may lead to new ways to predict the aggressiveness of prostate cancer and to novel therapies for preventing and treating the disease. The study published online today in the July 12 edition of Science.

12 Jul 2013

New discovery may help doctors determine role of microchimerism in human diseases

Some people possess a small number of cells in their bodies that are not genetically their own; this condition is known as microchimerism. It is difficult to determine potential health effects from this condition because of humans' relatively long life-spans.

12 Jul 2013

Researchers identify new cellular source for disease-fighting protein

Researchers at UT Southwestern Medical Center report the identification of a new cellular source for an important disease-fighting protein used in the body's earliest response to infection.

11 Jul 2013

Advanced genetics technologies may help predict patient outcomes in people with ALL

New evidence suggests that using advanced genetics technologies to monitor for remaining cancer cells after treatment may soon become an effective tool to inform treatment decisions and ultimately predict patient outcomes for patients with a particularly aggressive form of acute lymphocytic leukemia (ALL).

10 Jul 2013

Pharmacyclics submits ibrutinib NDA to FDA for two B-cell malignancies

Pharmacyclics, Inc. today announced that it has submitted a New Drug Application to the U.S. Food and Drug Administration for the investigational oral Bruton's tyrosine kinase inhibitor, ibrutinib, for two relapsed/refractory B-cell malignancy indications: mantle cell lymphoma and chronic lymphocytic leukemia/small lymphocytic lymphoma.

10 Jul 2013

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Amyotrophic Lateral Sclerosis (ALS) is a devastating motor neuron disease that rapidly atrophies the muscles, leading to complete paralysis. Despite its high profile - established when it afflicted the New York Yankees' Lou Gehrig - ALS remains a disease that scientists are unable to predict, prevent, or cure.

10 Jul 2013

Stem cells in the aesthetic industry: an interview with Dr. Norma Kassardjian

Stem Cells are special “master” cells in your body. Stem cells are the building blocks that can replicate into other kinds of cells like blood cells, heart, muscle, blood vessels and cartilage.

9 Jul 2013

CTI announces publication of preclinical, clinical data for pacritinib in Drugs of the Future 2013

Cell Therapeutics, Inc. today announced that a comprehensive article summarizing preclinical and clinical data for pacritinib, an oral JAK2/FLT3 inhibitor, authored by Srdan Verstovsek, M.D., Ph.D., et al., was published in the journal Drugs of the Future 2013.

3 Jul 2013

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

Yale Cancer Center scientists, together with colleagues at the Denver Police Crime Lab and the University of Colorado, have found evidence that a human metastatic tumor can arise when a leukocyte (white blood cell) and a cancer cell fuse to form a genetic hybrid.

3 Jul 2013

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

ARIAD Pharmaceuticals, Inc. today announced that the European Commission has granted a marketing authorization for Iclusig (ponatinib) as an orphan medicinal product for two indications.

2 Jul 2013

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Researchers at UCLA's Eli & Edythe Broad Center of Regenerative Medicine & Stem Cell Research have successfully established the foundation for using hematopoietic (blood-producing) stem cells from the bone marrow of patients with sickle cell disease to treat the disease.

2 Jul 2013

Scientists track down origins of fibrosis-promoting cells that scar and destroy organs

Scientists have tracked down and quantified the diverse origins of cells that drive fibrosis, the incurable, runaway wound-healing that scars and ultimately destroys organs such as the lungs, liver and kidneys.

2 Jul 2013

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

A study carried out in India examining the safety and efficacy of self-donated (autologous), transplanted bone marrow stem cells in patients with type 2 diabetes (TD2M), has found that patients receiving the transplants, when compared to a control group of TD2M patients who did not receive transplantation, required less insulin post-transplantation.

30 Jun 2013

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

Type 1 diabetes is an attack by the immune system of the islet of Langerhans within the pancreas. Basically, the islet of Langerhans harbor beta cells, which produce insulin and when the islets are attacked, the beta cells destruct and there is no more insulin. When the insulin level goes low, blood glucose levels go high and that creates a problem.

28 Jun 2013

BioLife Solutions, HemaCare enter into strategic partnership

BioLife Solutions, Inc., a leading developer, manufacturer and marketer of proprietary clinical grade hypothermic storage and cryopreservation freeze media for cells and tissues, and contract aseptic media manufacturer, and HemaCare Corporation, a leading supplier of blood derived cells and components for research and clinical applications, today announced a strategic relationship wherein HemaCare will market BioLife's HypoThermosol and CryoStor biopreservation media products and HemaCare's blood derived cells to the research and clinical communities.

25 Jun 2013

New study provides guidelines for stem cell transplantation in older MDS patients

A new study by an international team led by Dana-Farber Cancer Institute scientists provides the first statistically-based guidelines for determining whether a stem cell transplant is appropriate for older patients with myelodysplastic syndromes - the most common blood disorders in people over 60 years of age, and frequently a precursor for leukemia.

25 Jun 2013

Research findings suggest potent new therapeutic target for certain types of cancer

Scientists have discovered the survival secret to a genetic mutation that stokes leukemia cells, solving an evolutionary riddle and paving the way to a highly targeted therapy for leukemia.

21 Jun 2013

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

University Hospitals Case Medical Center clinical researchers have launched an innovative clinical trial, unique in its design, which will evaluate the ability of a patient's own stem cells to prevent leg amputations in end stage peripheral arterial disease (PAD).

20 Jun 2013

Bone Marrow News and Research

Further Reading

Excess fat in liver, muscle tissue and blood may increase risk of bone loss

New noninvasive technique for tracking stem cells after transplantation

Nerves play critical role in development and spread of prostate tumors, say researchers

New discovery may help doctors determine role of microchimerism in human diseases

Researchers identify new cellular source for disease-fighting protein

Advanced genetics technologies may help predict patient outcomes in people with ALL

Pharmacyclics submits ibrutinib NDA to FDA for two B-cell malignancies

Researcher uncover biomarkers from stem cells derived from bone marrow of ALS patients

Stem cells in the aesthetic industry: an interview with Dr. Norma Kassardjian

CTI announces publication of preclinical, clinical data for pacritinib in Drugs of the Future 2013

Metastasis can occur when leukocyte and cancer cell fuse to form genetic hybrid

ARIAD Pharmaceuticals' Iclusig gets EC marketing authorization for CML and Ph+ ALL treatment

UCLA researchers introduce gene therapy technique to treat sickle cell disease

Scientists track down origins of fibrosis-promoting cells that scar and destroy organs

Transplanted bone marrow stem cells in patients with type 2 diabetes reduce insulin use

Curing type 1 diabetes: an interview with Dr. Habib Zaghouani, MU School of Medicine

BioLife Solutions, HemaCare enter into strategic partnership

New study provides guidelines for stem cell transplantation in older MDS patients

Research findings suggest potent new therapeutic target for certain types of cancer

Researchers launch clinical trial on stem cells to prevent amputations in end stage PAD

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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