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$Phase 1 clinical trial of XMT-1107 initiated in patients with refractory advanced solid tumors$

Phase 1 clinical trial of XMT-1107 initiated in patients with refractory advanced solid tumors

Mersana Therapeutics, a platform-based cancer therapeutics company, today announced that it has initiated a Phase 1 clinical trial to study the safety and pharmacokinetics of XMT-1107 in patients with refractory advanced solid tumors. XMT-1107 is a novel anti-angiogenic fumagillin analog that employs Mersana's Fleximer platform. Mersana's XMT-1001, a conjugate of Fleximer and camptothecin, is currently completing a Phase 1 study.

23 Jun 2010

German IVF Register reports one-millionth treatment cycle in reproductive medicine

Dr. Klaus Buhler, President of the German IVF Register, has reported the one-millionth treatment cycle in reproductive medicine recorded by the IVF Register in Germany this year. Presently, ninety per cent of all centers for in-vitro fertilization (IVF) in Germany collect data from reproductive treatments using RecDate Advance by Merck Serono - a database system developed by the IT consulting firm CRITEX, and marketed under the name MedITEX IVF.

23 Jun 2010

K-State chemical engineer patents chemical structure to make natural personal care products in lab

A Kansas State University chemical engineer has developed and patented a chemical structure to make all-natural personal care products and purer pharmaceuticals in the laboratory.

23 Jun 2010

Researchers treat acute kidney injury using cells genetically reprogrammed to produce protein

A protein whose primary role is in the embryonic development of kidneys may play a future role in treating kidney failure. Indiana University School of Medicine researchers have successfully treated acute kidney injury in laboratory experiments using cells that were genetically reprogrammed to produce the protein. The research suggests there could be a potential future treatment using such cells delivered intravenously instead of surgically.

23 Jun 2010

World Bank provides over $63M for multi-country lab network in East Africa region

East African Business Week/allAfrica.com reports on the recent decision by the World Bank to back the creation of "a unique regional network of 25 public health laboratories" in Kenya, Tanzania, Uganda and Rwanda with $63.66 million in support.

23 Jun 2010

Scientists apply fuzzy logic modeling to predict aging progresses in cells, organisms

The process of aging disturbs a broad range of cellular mechanisms in a complex fashion and is not well understood. Computer models using fuzzy logic might help to unravel these complexities and predict how aging progresses in cells and organisms, according to a study from Drexel University in Philadelphia and Children's Hospital Boston.

23 Jun 2010

Proven Diagnostics signs contract to provide comprehensive laboratory services to Highmark members

Proven Diagnostics, a clinical diagnostic laboratory located in Bethlehem, Pa., announced today that it has signed a contract with Highmark, the largest health insurer in Pennsylvania.

23 Jun 2010

Understanding HIV viral protein structure could lead to new molecular medicines: Study

The UK's National Physical Laboratory is involved in a collaborative project that is helping to further the understanding of HIV viral protein structure which could lead to new molecular medicines.

23 Jun 2010

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

OvaGene Oncology Inc., a biotechnology company specializing in the development and commercialization of personalized DNA-based diagnostics for gynecologic cancer, announced today the opening of its new clinical and research laboratory in Irvine, California. This state-of-the-art facility will serve as the central headquarters for operations, research, and molecular clinical lab testing.

23 Jun 2010

Benioff family gifts $100 million for construction of new UCSF Children's Hospital at Mission Bay

Salesforce.com chairman and CEO Marc Benioff and his family have given a $100 million private gift to help fund the construction of the new UCSF Children's Hospital at the UCSF Mission Bay campus near downtown San Francisco. The gift is both the largest gift the donors have ever made and the largest gift ever granted specifically to the UCSF Children's Hospital.

22 Jun 2010

Ethicon Endo-Surgery renews research collaboration agreement with UC and Metabolic Diseases Institute

Ethicon Endo-Surgery, Inc. (EES) today announced it has renewed its research collaboration agreement with the University of Cincinnati (UC) and its Metabolic Diseases Institute (MDI). The three-year, $13.5M grant extension, is part of the EES Metabolic Applied Research Strategy (MARS), which also includes research from GI Metabolism Laboratory and Weight Center at the Massachusetts General Hospital (MGH).

22 Jun 2010

Scientists complete comparative analysis of bacterial communities living in human nose, throat

Scientists have completed the most comprehensive comparative analysis to date of bacterial communities inhabiting the human nose and throat, which could provide new insights into why some individuals become colonized with pathogens while others do not. They release their findings today in mBio- the online open-access journal published by the American Society for Microbiology.

22 Jun 2010

Fructose makes cells mature into fat cells in belly fat, study finds

Fructose, the sugar widely used as high-fructose corn syrup in soft drinks and processed foods, often gets some of the blame for the widespread rise in obesity. Now a laboratory study has found that when fructose is present as children's fat cells mature, it makes more of these cells mature into fat cells in belly fat and less able to respond to insulin in both belly fat and fat located below the skin.

22 Jun 2010

CCBC fourth-quarter fiscal 2010 net revenues up 24.6%

China Cord Blood Corporation, China's leading provider of cord blood collection, laboratory testing, hematopoietic stem cell processing, and stem cell storage services, today announced preliminary unaudited financial results for the fourth quarter and full year fiscal 2010.

22 Jun 2010

New report measures growing adoption of centralized ECG services

ERT, a global provider of technology and services to the pharmaceutical, biotechnology and medical device industries, announced today the availability of a new report, conducted by the Tufts Center for the Study of Drug Development, mapping the growing adoption of centralized ECG (electrocardiogram) services. The industry-wide report measures the current and anticipated adoption levels of centralized ECGs in clinical trials.

22 Jun 2010

Protea Biosciences, Mayoly-Spindler commence Phase I/IIA human clinical trial for new recombinant Lipase

Protea Biosciences, Inc., a leading developer of new technology for pharmaceutical research, announced today that the company, in partnership with Mayoly-Spindler, a European pharmaceutical company, has commenced a Phase I/IIA human clinical trial for a new recombinant Lipase.

22 Jun 2010

New legal, ethical framework needs to be placed around banking of human biological material: Review

A lawyer and researcher at the Johns Hopkins Berman Institute of Bioethics says a new legal and ethical framework needs to be placed around the donation and banking of human biological material, one that would more clearly define the terms of the material's use - and address donor expectations before research begins.

22 Jun 2010

SynCon DNA vaccine shows advantages in magnitude and breadth of immune responses in non-human primates

Inovio Pharmaceuticals, Inc., a leader in the development of therapeutic and preventive vaccines against cancers and infectious diseases, announced today that the peer-reviewed journal Molecular Therapy has published a paper entitled "Comparative Analysis of Immune Responses Induced by Vaccination With SIV Antigens by Recombinant Ad5 Vector or Plasmid DNA in Rhesus Macaques." The paper, co-authored by researchers from Merck, University of Pennsylvania School of Medicine, and Inovio Pharmaceuticals, notes that significant advances in the design, formulation, and delivery of DNA plasmid-based vaccines have dramatically increased their ability to induce antigen-specific immune responses.

22 Jun 2010

Ultrasound-guided diffuse optical tomography holds promise for ascertaining early-stage invasive breast cancer

By combining two relatively inexpensive technologies based on sound and light waves, researchers hope to lower the rate at which women undergo breast biopsies for suspicious lesions. Results of the study on ultrasound-guided optical tomography are published in the online edition and the August print issue of Radiology.

22 Jun 2010

Connecticut is first state in U.S to expand coverage for low-income residents under Affordable Care Act

Connecticut is the first state in the nation to permanently add low-income adults to its Medicaid program under the new Affordable Care Act, Health and Human Services Secretary Kathleen Sebelius announced today.

22 Jun 2010

Laboratory News and Research

Phase 1 clinical trial of XMT-1107 initiated in patients with refractory advanced solid tumors

German IVF Register reports one-millionth treatment cycle in reproductive medicine

K-State chemical engineer patents chemical structure to make natural personal care products in lab

Researchers treat acute kidney injury using cells genetically reprogrammed to produce protein

World Bank provides over $63M for multi-country lab network in East Africa region

Scientists apply fuzzy logic modeling to predict aging progresses in cells, organisms

Proven Diagnostics signs contract to provide comprehensive laboratory services to Highmark members

Understanding HIV viral protein structure could lead to new molecular medicines: Study

OvaGene Oncology opens new advanced molecular research and clinical laboratory facility

Benioff family gifts $100 million for construction of new UCSF Children's Hospital at Mission Bay

Ethicon Endo-Surgery renews research collaboration agreement with UC and Metabolic Diseases Institute

Scientists complete comparative analysis of bacterial communities living in human nose, throat

Fructose makes cells mature into fat cells in belly fat, study finds

CCBC fourth-quarter fiscal 2010 net revenues up 24.6%

New report measures growing adoption of centralized ECG services

Protea Biosciences, Mayoly-Spindler commence Phase I/IIA human clinical trial for new recombinant Lipase

New legal, ethical framework needs to be placed around banking of human biological material: Review

SynCon DNA vaccine shows advantages in magnitude and breadth of immune responses in non-human primates

Ultrasound-guided diffuse optical tomography holds promise for ascertaining early-stage invasive breast cancer

Connecticut is first state in U.S to expand coverage for low-income residents under Affordable Care Act

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