Laboratory News and Research

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Smokers' breath contains 2,5-dimethylfuran

If you smoke, your breath contains 2,5-dimethylfuran. A team of Catalan researchers have proved that the presence of this chemical compound indicates that a person has smoked in the last three days. This substance does not appear in the breath of non-smokers, unless they have been in direct contact with tobacco smoke for a long time.

20 May 2010

EPFL develops flowing 3D model of cardiovascular system that predicts heart attacks

The supercomputer Cadmos, installed at the Ecole Polytechnique Fédérale de Lausanne (EPFL) in August of 2009, has bared one of its first fruits: the Laboratory of Multiscale Modeling of Materials has recently developed a computer program the accurately models the complex system of blood flow in the heart for individuals at an unheard-of precision of ten millionths of a meter or ten microns.

20 May 2010

Basque researchers find new Alzheimer's-related mechanism

Researchers from the University of the Basque Country have found a new Alzheimer's-related mechanism that could give rise to the development of new therapies against this disease. The study was recently published in the Cell Calcium journal, and the authors have already applied for a European patent to protect the commercial exploitation of this new discovery.

20 May 2010

Dynamic testing approach for HIV/AIDS diagnostics

A relatively simple electronic gadget could speed up HIV/AIDS diagnostics and improve accuracy particularly in parts of the world with very limited access to healthcare workers. The device is described in the International Journal of Biomedical Engineering and Technology.

20 May 2010

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

Dr. Ming-Heng Wu of the Institute of Basic Medical Sciences at National Cheng Kung University (NCKU), Taiwan, in collaboration with Prof. Chawnshang Chang's laboratory of University of Rochester (UR), United States, have discovered that androgen receptors (AR) can promote hepatitis B virus-induced hepatocarcinogenesis through modulation of hepatitis B virus (HBV) RNA transcription.

20 May 2010

Home portable monitor testing can be used to diagnose, manage patients with OSA: Study

Patients with suspected obstructive sleep apnea may no longer have to spend an expensive and uncomfortable night at a sleep center to monitor their sleep-disordered breathing. According to new research, those who performed sleep testing in their home with portable monitors showed similar improvements after three months of treatment with continuous positive airway pressure in daytime function as compared to patients who underwent overnight testing in a sleep center.

20 May 2010

New Agilent SurePrint G3 Gene Expression Microarrays introduced

Agilent Technologies Inc. today introduced Agilent SurePrint G3 Gene Expression Microarrays, providing up to one million features per standard 1-by-3-inch slide for added throughput, unique coverage which includes both coding and non-coding RNA, and cost effectiveness.

20 May 2010

Role of neurotransmitter acetylcholine may suggest new treatment for Parkinson's disease: Researchers

Chicago and Montreal researchers studying the lowly lamprey eel have identified an overlooked nervous system pathway running parallel to known brainstem locomotor command circuitry in vertebrates such as birds, fishes and mammals.

20 May 2010

Live malaria parasites in the skin shut down immune responses and block vaccine function: Study

Why one after another new malaria vaccine tests well in the laboratory but fails in field trials has frustrated legions of malaria researchers, and has been the main stumbling block to malaria eradication. Now, a research team from Germany has unraveled that puzzle and shown that the problem is all about the skin and how it controls the immune system. The implications are profound.

20 May 2010

Illusion challenges human visual system and brain

A new amazing illusion proves that defying gravity may be as simple as your point of view.

20 May 2010

New study shows CDPK1 controls toxoplasma's ability to secrete microneme proteins

Researchers at Washington University School of Medicine in St. Louis have identified a parasite protein that has all the makings of a microbial glass jaw: it's essential, it's vulnerable and humans have nothing like it, meaning scientists can take pharmacological swings at it with minimal fear of collateral damage.

20 May 2010

Trius awarded new DTRA contract for developing novel antibiotics against gram-negative bacterial pathogens

Trius Therapeutics, Inc. today announced that it has been awarded a new four and a half year contract from the Defense Threat Reduction Agency (DTRA), an agency within the U.S. Department of Defense, for the development of novel antibiotics directed against gram-negative bacterial pathogens. Trius may receive up to $29.5 million in support of development efforts under the new DTRA contract, which is funded as part of DTRA's Transformational Medical Technologies Initiative (TMTI).

20 May 2010

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

Researchers from the Kimmel Cancer Center at Jefferson have found that Stat5, a signaling protein previously found to be key to survival of prostate cancer, is also involved in metastasis.

20 May 2010

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

Biomedical research in Arkansas has received a $14.7 million boost over five years from the National Institutes of Health (NIH) to continue expanding and improving biomedical research in the state.

20 May 2010

AACE, AME and ETA jointly publish guidelines for diagnosis and management of thyroid nodules

Three of the world's most respected medical associations for the treatment of thyroid disease recently issued joint guidelines for the diagnosis and management of thyroid nodules. The American Association of Clinical Endocrinologists, the Associazione Medici Endocrinologi and European Thyroid Association jointly published the guidelines online this week, and the executive summary will be published in the next issue of their respective journals.

20 May 2010

FDA grants 510(k) market clearance for EraGen's MultiCode-RTx HSV 1&2 Kit

EraGen Biosciences Inc. today announced that the U.S. Food and Drug Administration (FDA) has granted 510(k) market clearance for EraGen's MultiCode®-RTx HSV 1&2 Kit.

20 May 2010

ABBOTT PRISM Chagas test receives FDA approval

Abbott received Biologic License Application (BLA) approval from the United States Food and Drug Administration (FDA) for the ABBOTT PRISM Chagas test. The test is a fully automated blood screening assay that can detect antibodies to Trypansoma cruzi (T. cruzi), a parasite found only in the Americas and most commonly acquired through contact with the blood-sucking triatomine or "kissing bug."

19 May 2010

PrimeWire PRESTIGE Pressure Guide Wire receives 510(k) clearance, CE Mark approval

Volcano Corporation announced today it received both 510(k) clearance and CE Mark approval for its PrimeWire PRESTIGE Pressure Guide Wire for use with patients who have both single-vessel and multi-vessel disease. This next generation pressure wire is compatible with Volcano's full suite of integrated multi-modality consoles and stand-alone physiology systems as well as various hemodynamic monitoring systems.

19 May 2010

Experimental evolution used to develop new strains of bacteria for use as probiotic substances

When the forces of evolution took over an experimental strain of bacteria, it derailed an experiment Duke and NC State researchers thought they were conducting, but led to something much more profound instead.

19 May 2010

BBSRC, EPSRC fund £1.5M for synthetic biology projects under EuroSYNBIO Programme

Four new projects, announced today, will develop biological methods that offer a new approach to antibiotic production, power generation for extremely small mechanical components, new classes of medicines and innovative techniques to study cell biology.

19 May 2010

Laboratory News and Research

Smokers' breath contains 2,5-dimethylfuran

EPFL develops flowing 3D model of cardiovascular system that predicts heart attacks

Basque researchers find new Alzheimer's-related mechanism

Dynamic testing approach for HIV/AIDS diagnostics

Androgen receptors promote hepatitis B virus in growth and development of hepatoma cells

Home portable monitor testing can be used to diagnose, manage patients with OSA: Study

New Agilent SurePrint G3 Gene Expression Microarrays introduced

Role of neurotransmitter acetylcholine may suggest new treatment for Parkinson's disease: Researchers

Live malaria parasites in the skin shut down immune responses and block vaccine function: Study

Illusion challenges human visual system and brain

New study shows CDPK1 controls toxoplasma's ability to secrete microneme proteins

Trius awarded new DTRA contract for developing novel antibiotics against gram-negative bacterial pathogens

Over-expression of Stat5 protein leads to deadly spread of prostate cancer: Study

UAMS and partners receive $14.7M NIH grant for extension of biomedical research

AACE, AME and ETA jointly publish guidelines for diagnosis and management of thyroid nodules

FDA grants 510(k) market clearance for EraGen's MultiCode-RTx HSV 1&2 Kit

ABBOTT PRISM Chagas test receives FDA approval

PrimeWire PRESTIGE Pressure Guide Wire receives 510(k) clearance, CE Mark approval

Experimental evolution used to develop new strains of bacteria for use as probiotic substances

BBSRC, EPSRC fund £1.5M for synthetic biology projects under EuroSYNBIO Programme

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