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Groundbreaking cystic fibrosis clinical trial to proceed after renewed funding

The team of scientists based in Edinburgh, Oxford and London were developing a treatment which involves putting genes into the lungs of patients suffering the fatal, inherited wasting disease, passed early clinical trials in 2010. But the recession badly affected the Cystic Fibrosis Trust, the charity that had funded the programme, and work had to stop last year just as the consortium was closing in on its goal.

19 Mar 2012

Soy-based S-equol lowers HbA1c, LDL cholesterol and improves vascular stiffness

A 12-week treatment of the fermented soy germ-based nutritional supplement containing S-equol significantly lowered hemoglobin A1c (HbA1c), LDL cholesterol and improved vascular stiffness, all factors that occur as part of metabolic syndrome, according to a first-of-its-kind peer-reviewed study reported in a poster at the Women's Health 2012 annual meeting.

19 Mar 2012

Eating salmon benefits pregnant women and their babies

University of Granada researchers have proven that eating two servings of salmon reared at a fish farm (enriched with omega-3 fatty acids and only slightly contaminated) a week during pregnancy is beneficial both for the mother and child.

19 Mar 2012

Hive Health Media article cites several tips to improve skin's health

Hive Health Media has recently published an article that presents several tips for those individuals who are seeking anti-aging solutions. As a cultural movement, as well as a healthcare trend, anti-aging has become a popular activity among many generations.

19 Mar 2012

Tiny Tim may have suffered from rickets and TB

Le Bonheur Professor Russell Chesney, M.D. believes he knows what was ailing Tiny Tim, the iconic character from Charles Dickens' "A Christmas Carol." Based on detailed descriptions of both the symptoms and living conditions of 18th century London, Dr. Chesney hypothesizes that Tiny Tim suffered from a combination of rickets and tuberculosis (TB).

17 Mar 2012

BRG1 gene loss implies lack of response of cells to retinoic acid and steroids

Retinoic acid (vitamin A) and steroids are hormones found in our body that protect against oxidative stress, reduce inflammation and are involved in cellular differentiation processes. One of the characteristics of tumours is that their cells have lost the ability to differentiate; therefore these hormones have useful properties to prevent cancer. Currently, retinoic acid and steroids are being used to treat some types of leukaemia.

16 Mar 2012

Food-insecure mothers more likely to develop obesity

Mothers who financially struggle to provide food for their families tend to put themselves at risk for obesity while trying to feed their children, according to Penn State sociologists.

16 Mar 2012

Link between white rice consumption and risk of type 2 diabetes

The risk of type 2 diabetes is significantly increased if white rice is eaten regularly, claims a study published today on bmj.com.

16 Mar 2012

Scientists discover cells that chaperone food antigens in the intestine

With every meal, immune cells in the intestine stand like sentries at a citadel, turning away harmful bacteria but allowing vitamins and nutrients to pass. Now, researchers at Washington University School of Medicine in St. Louis have identified the cells that chaperone food antigens, or proteins, in the intestine so that the immune system doesn't mount an attack.

15 Mar 2012

Viewpoints: Health law savings questioned; Ryan-Wyden plan for all; Penalizing hospitals may not save money

As we approach the second anniversary of ObamaCare, it's worth re-examining some of the claims its proponents made about the impact of the law on health-care costs. Three of the law's most-touted cost-control measures have already been shown to be unlikely to succeed.

15 Mar 2012

Highlights from Journal of the American Academy of Orthopaedic Surgeons

The Spine Patient Outcomes Research Trial (SPORT) is the first comprehensive study to look at the effectiveness of different treatments for low back and leg pain. It was designed to provide data and outcomes to guide doctors and their patients in their treatment choices for three common spinal disorders: intervertebral disk herniation (IDH), degenerative spondylolisthesis (DS), and lumbar spinal stenosis (LSS).

14 Mar 2012

Earlier start of micronutrient supplementation better for pregnant women and the unborn child

When pregnant women take supplements with micronutrients (vitamins and minerals), the growth of their unborn child improves. The improvement is cumulative, so researchers from the Antwerp Institute of Tropical Medicine report : the earlier in pregnancy the supplementation starts, the better. In developing countries, where women often have a poor diet, these supplements really make a difference.

14 Mar 2012

Antidepressant could help the workings of anticancer drug used in leukemia

The study by scientists at the Institute of Cancer Research found that tranylcypromine (TCP) – which can be used to treat psychotic depressive states - can make cancer cells vulnerable to the effects of a vitamin A-derivative drug called ATRA.

13 Mar 2012

Swaddling babies tight could lead to hip problems

Swaddling babies is back in vogue as many mothers are convinced that wrapping babies tightly makes them feel more secure. However a children's surgeon at Southampton General Hospital has warned that the practice of tight swaddling, where both the arms and legs are wrapped up, is causing an increase in hip problems.

13 Mar 2012

Many Americans deficient in magnesium, sulfur and sulfate

Many Americans are deficient in magnesium, sulfur and sulfate, experts say. It's a problem that causes a variety of health issues that could be prevented with small changes to diet and behavior, including frequent soaks in Epsom salt.

12 Mar 2012

ITQB, REQUIMTE convert solid antibiotic ampicilin into an ionic liquid form

In a daring move into the biomedical arena, ITQB chemists from the Molecular Thermodynamics Lab and collaborators from REQUIMTE have managed to convert the solid antibiotic ampicilin into an ionic liquid form, a method that may be extended to other pharmaceutical compounds with benefits for their administration. The work is now published in Medicinal Chemistry Communications.

12 Mar 2012

Tranylcypromine shows promise against AML

A retinoid called all-trans retinoic acid (ATRA), which is a vitamin A-derivative, is already used successfully to treat a rare sub-type of acute myeloid leukemia (AML), however this drug has not been effective for the more common types of AMLs.

12 Mar 2012

Even low-dose nanoparticles could have big impact on long-term health

Nanoparticles are everywhere. From cosmetics and clothes, to soda and snacks. But as versatile as they are, nanoparticles also have a downside, say researchers at Binghamton University and Cornell University in a recent paper published in the journal Nature Nanotechnology. These tiny particles, even in low doses, could have a big impact on our long-term health.

9 Mar 2012

Vitamin D deficiency may increase risk of mortality in institutionalized elderly patients

The majority of institutionalized elderly female patients are vitamin D deficient and there is an inverse association of vitamin D deficiency and mortality, according to a recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology and Metabolism.

7 Mar 2012

Tree nut consumption may reduce weight and health risks

March is National Nutrition Month and as the spotlight shines on all things healthy, celebrate with a mindful snack that loves you back-California pistachios.

7 Mar 2012