Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

Research explores whether increasing Medicare payments can improve nursing facility care

Regenstrief Institute and Indiana University Center for Aging Research investigators are testing whether providing nursing homes and the doctors and nurse practitioners who care for their residents with increased Medicare payments can further reduce avoidable hospitalizations.

10 Oct 2018

New DNA test can predict adult heart attack risk much earlier in life

People at high risk of a heart attack in adulthood could be spotted much earlier in life with a one-off DNA test, according to new research part-funded by the British Heart Foundation and published today in the Journal of the American College of Cardiology.

9 Oct 2018

Two related enzymes have opposing roles in heart failure

Two related enzymes have opposing roles in mouse heart muscle cells exposed to pressure overload, according to a recent study published in the Proceedings of the National Academy of Sciences, USA.

9 Oct 2018

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

9 Oct 2018

Study finds suboptimal antithrombotic care in AFib patients with cancer history

Atrial fibrillation patients with a history of cancer are less likely to see a cardiologist or fill anticoagulant prescriptions compared with AFib patients who never had cancer, according to a study in the Journal of the American College of Cardiology.

8 Oct 2018

RNA sequencing method uncovers new insights into biological events in heart disease

Scientists using a powerful new technology that sequences RNA in 20,000 individual cell nuclei have uncovered new insights into biological events in heart disease.

5 Oct 2018

Lilly, Boehringer Ingelheim present full results of cardiovascular outcome trial, CARMELINA

Boehringer Ingelheim and Eli Lilly and Company today presented the full results of the long-term cardiovascular outcome trial, CARMELINA®, which studied the impact of Trajenta® (linagliptin) on cardiovascular and kidney safety in adults with type 2 diabetes at high risk for heart and/or kidney disease.

5 Oct 2018

UB receives £1.78 million to find new therapies for treating heart failure and diabetes

The University of Birmingham has been awarded £1.78 million by the Wellcome Trust for research aimed at finding new therapies to treat diseases such as heart failure, diabetes and neurodegenerative disorders.

29 Sep 2018

Medicare eases readmission penalties against safety-net hospitals

On orders from Congress, Medicare is easing up on its annual readmission penalties on hundreds of hospitals serving the most low-income residents, records released last week show.

28 Sep 2018

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

Pfizer Inc. today announced that the U.S. Food and Drug Administration has approved VIZIMPRO [vih-ZIM-pro] (dacomitinib), a kinase inhibitor for the first-line treatment of patients with metastatic non-small cell lung cancer with epidermal growth factor receptor exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test.

28 Sep 2018

UH pharmacologist receives NIH grant to improve kidney function in older people

Mohammad Asghar, associate professor of pharmacology at the University of Houston, has been awarded $459,000 from the National Institutes of Health/National Institute on Aging to improve kidney function in people 65 and older, a population at higher risk for developing impaired kidney function.

27 Sep 2018

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Mesoblast Limited today announced that Mesoblast's proprietary allogeneic mesenchymal precursor cell heart failure product candidate MPC-150-IM for use in children with hypoplastic left heart syndrome was featured at the First Cardiac Regenerative Symposium for Congenital Heart Disease in Baltimore, Maryland on the weekend.

26 Sep 2018

Research reveals three-dimensional structure of membrane channel that controls blood pressure

New research for the first time reveals the three-dimensional structure of a membrane channel that's critical in controlling blood pressure.

26 Sep 2018

Ancora Heart announces positive data of study evaluating AccuCinch Ventricular Repair System

Ancora Heart, Inc., a company developing a novel therapy to address heart failure, today announced positive clinical data from the company's recently expanded U.S. early feasibility study evaluating the safety of the investigational AccuCinch Ventricular Repair System designed for the treatment of heart failure and functional mitral regurgitation.

24 Sep 2018

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

AstraZeneca today announced positive results from the Phase III DECLARE-TIMI 58 cardiovascular outcomes trial for FARXIGA, the broadest SGLT-2 inhibitor CVOT conducted to date.

24 Sep 2018

Study: Transcatheter mitral valve repair reduces mortality for patients with mitral regurgitation

A multicenter clinical trial has found that a minimally invasive procedure called transcatheter mitral valve repair significantly reduced hospitalizations and mortality for heart failure patients with moderate-to-severe or severe functional mitral regurgitation.

24 Sep 2018

Most patients who underwent transcatheter valve replacement experience prosthesis-patient mismatch

In the largest multi-institutional study to date, led by researchers from Penn Medicine, the team found that among patients who underwent a transcatheter aortic valve replacement, a high number experienced severe and moderate cases of prosthesis-patient mismatch--meaning the implanted heart valve is too small for the patient which can lead to inadequate blood flow.

24 Sep 2018

King's commemorates opening of new NMR facility with one-day symposium

On Tuesday 4 September the Nuclear Magnetic Resonance facility celebrated the refurbishment of their suite of spectrometers by hosting a one-day symposium.

24 Sep 2018

Transcatheter mitral-valve repair in patients with heart failure

A new heart device called the MitraClip (from Abbott) has been shown to benefit patients with heart failure and reduce death rates among them significantly.

23 Sep 2018

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Non-steroidal anti-inflammatory drugs, or NSAIDs, are commonly used as inflammation blockers worldwide. However, recent clinical data show these painkillers can have serious side effects that create some risk of heart attacks, strokes, and kidney or heart failure.

21 Sep 2018

Heart Failure News and Research

Further Reading

Research explores whether increasing Medicare payments can improve nursing facility care

New DNA test can predict adult heart attack risk much earlier in life

Two related enzymes have opposing roles in heart failure

Massively parallel single-nucleus RNA sequencing reveals insights into heart disease

Study finds suboptimal antithrombotic care in AFib patients with cancer history

RNA sequencing method uncovers new insights into biological events in heart disease

Lilly, Boehringer Ingelheim present full results of cardiovascular outcome trial, CARMELINA

UB receives £1.78 million to find new therapies for treating heart failure and diabetes

Medicare eases readmission penalties against safety-net hospitals

Pfizer announces FDA approval of VIZIMPRO for first-line treatment of EGFR-mutated metastatic NSCLC

UH pharmacologist receives NIH grant to improve kidney function in older people

Mesoblast’s MPC therapy for children featured at symposium for congenital heart disease

Research reveals three-dimensional structure of membrane channel that controls blood pressure

Ancora Heart announces positive data of study evaluating AccuCinch Ventricular Repair System

FARXIGA receives positive results in Phase III DECLARE-TIMI 58 cardiovascular outcomes trial

Study: Transcatheter mitral valve repair reduces mortality for patients with mitral regurgitation

Most patients who underwent transcatheter valve replacement experience prosthesis-patient mismatch

King's commemorates opening of new NMR facility with one-day symposium

Transcatheter mitral-valve repair in patients with heart failure

UAB researchers study dysfunction of the immune system associated with NSAID carprofen

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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