Cell News and Research

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Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

A synthetic peptide appears to directly disrupt the destructive inflammation that occurs in nephritis, enabling the kidneys to better recover and maintain their important functions, investigators report.

25 Mar 2019

Exposure to dim light at night may contribute to spread of breast cancer to bones

Exposure to dim light at night, which is common in today's lifestyle, may contribute to the spread of breast cancer to the bones, researchers have shown for the first time in an animal study.

25 Mar 2019

Chemicals in household dust promote development of fat cells in cell model

Endocrine-disrupting chemicals present in household dust promote the development of fat cells in a cell model and could contribute to increased growth in children relative to their age, according to research to be presented Monday, March 25 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Exposure to particulate air pollution may lead to reduced sperm production

Exposure to tiny air pollution particles may lead to reduced sperm production, suggests new research in mice to be presented Monday, March 25 at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Modulating stiffness of blood-forming stem cells could facilitate mobilization procedures

Scientists at Winship Cancer Institute of Emory University, Children's Healthcare of Atlanta and Georgia Tech have found that modulating blood-forming stem cells' stiffness could possibly facilitate mobilization procedures used for stem cell-based transplants.

25 Mar 2019

Nervous system relies on guidance cues for neuronal axons to reach destinations

Similar to the dozens of Sherpas that guide hikers up treacherous Himalayan mountains to reach a summit, the nervous system relies on elaborate timing and location of guidance cues for neuronal axons--threadlike projections--to successfully reach their destinations in the body.

25 Mar 2019

Hemoglobin A1c blood test does not detect diabetes in most patients, shows study

The hemoglobin A1c blood test is widely used to diagnose type 1 and type 2 diabetes, but it is actually unable to detect the disease in most patients, according to a new study presented Saturday, March 23, at a news conference at ENDO 2019, the Endocrine Society's annual meeting in New Orleans, La.

25 Mar 2019

Anti-TB drugs can increase susceptibility to Mtb reinfection

Current treatments for tuberculosis are very effective in controlling TB infection caused by Mycobacterium tuberculosis. They don't, however, always prevent reinfection. Why this happens is one of the long-standing questions in TB research.

22 Mar 2019

Antidepressant drugs may not work when neurons are out of shape

elective serotonin reuptake inhibitors are the most commonly prescribed medication for major depressive disorder, yet scientists still do not understand why the treatment does not work in nearly thirty percent of patients with MDD.

22 Mar 2019

High-fat, high-sugar diet in mouse mothers causes problems in the hearts of offspring

A diet high in fats and sugars is known for its unhealthy effects on the heart. Scientists now have found that a high-fat, high-sugar diet in mouse mothers before and during pregnancy causes problems in the hearts of their offspring, and that such problems are passed down at least three generations, even if the younger generations only eat a standard mouse chow diet.

22 Mar 2019

Study provides new pathway for controlling inflammation

UT Southwestern researchers have identified two proteins that act as gatekeepers to dampen a potentially life-threatening immune response to chronic infection.

22 Mar 2019

Study provides new insight into blood cell and immune cell production

A healthy adult makes about 2 million blood cells every second, and 99 percent of them are oxygen-carrying red blood cells. The other one percent are platelets and the various white blood cells of the immune system.

22 Mar 2019

Repurposing drugs to outsmart cancers

In an article published today by SAGE Publishing, investigators from The Nagourney Cancer Institute and The Albert Einstein Israelite Hospital in São Paulo, Brazil, announced a new approach to identifying effective treatments for patients with advanced metastatic cancers. A drug commonly used to treat kidney and liver cancer was discovered effective for breast cancer, which may open new drug therapies to patients regardless of tumor type.

22 Mar 2019

Researchers develop new tool for imaging large groups of neurons in living animals

Researchers have developed a microscope specifically for imaging large groups of interacting cells in their natural environments.

22 Mar 2019

A new way to visualize the immune cell "landscape" of bowel cancer tumors

University of Otago scientists have discovered a way to view the immune cell "landscape" of bowel cancer tumours, paving the way towards more individualised medicine and treatment for many other diseases in future.

22 Mar 2019

Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia

Most patients with chronic myelogenous leukemia can be treated with tyrosine kinase inhibitors. These drugs are highly effective and lead to deep remission and prolonged survival.

22 Mar 2019

Lung cancer survivor recounts her lifetime struggles

By any measure, lung cancer patients have it rough. But Maryland resident and special education teacher Montessa Lee has been through a particularly arduous ordeal.

22 Mar 2019

New nanotechnology approach shows promise in treating triple negative breast cancer

Unlike the three most common forms of breast cancer, triple negative breast cancer has no currently approved targeted therapies for treatment. That was one of the reasons it was chosen as a disease area of focus for the Indiana University Precision Health Grand Challenge initiative, aimed to research and develop better treatments, cures or preventions, as quickly as possible.

22 Mar 2019

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

Xiaojun "Lance" Lian, assistant professor of biomedical engineering, was one of three recipients of the College of Engineering's ENGineering for Innovation & Entrepreneurship grant for "Small Molecule-Based Definitive Endoderm Kit and Pancreatic Progenitor Kit for Stem Cell Research and Therapy."

22 Mar 2019

City of Hope exhibits current studies and data on cancer therapies at AACR

City of Hope, a world-renowned independent research and treatment center for cancer and diabetes, will showcase ongoing studies and data on chimeric antigen receptor T cell therapy, immunotherapy against solid tumors and more at the American Association for Cancer Research annual meeting from March 29 through April 3 in Atlanta.

22 Mar 2019

Cell News and Research

Synthetic peptide appears to disrupt inflammation and protect kidneys from nephritis

Exposure to dim light at night may contribute to spread of breast cancer to bones

Chemicals in household dust promote development of fat cells in cell model

Exposure to particulate air pollution may lead to reduced sperm production

Modulating stiffness of blood-forming stem cells could facilitate mobilization procedures

Nervous system relies on guidance cues for neuronal axons to reach destinations

Hemoglobin A1c blood test does not detect diabetes in most patients, shows study

Anti-TB drugs can increase susceptibility to Mtb reinfection

Antidepressant drugs may not work when neurons are out of shape

High-fat, high-sugar diet in mouse mothers causes problems in the hearts of offspring

Study provides new pathway for controlling inflammation

Study provides new insight into blood cell and immune cell production

Repurposing drugs to outsmart cancers

Researchers develop new tool for imaging large groups of neurons in living animals

A new way to visualize the immune cell "landscape" of bowel cancer tumors

Understanding maintenance of quiescent stem cells in chronic myelogenous leukemia

Lung cancer survivor recounts her lifetime struggles

New nanotechnology approach shows promise in treating triple negative breast cancer

Lian wins ENGINE grant for stem-cell-based therapy to treat Type 1 diabetes

City of Hope exhibits current studies and data on cancer therapies at AACR

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