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New approach to tackling chronic inflammatory diseases

An EU-funded project has developed new approaches to tackling chronic inflammatory diseases. These will be used to create precise and individualized treatment options, potentially leading to faster diagnosis, more effective treatments and even cures.

1 Mar 2019

New tool uncovers molecular causes of different diseases

Princeton University researchers are gaining new insights into the causes and characteristics of diseases by harnessing machine learning to analyze molecular patterns across hundreds of diseases simultaneously.

1 Mar 2019

Johns Hopkins study sheds light on resistance to radiation treatment

A new Johns Hopkins study offers promise towards someday being able to non-invasively examine changes in cancerous tumors to determine whether they'll respond to radiation treatment, before treatment even begins.

1 Mar 2019

Research identifies super-enhancers as novel target for pancreatic ductal adenocarcinoma

Differential H3K27AC marks were identified at enhancer regions of genes including c-MYC, MED1, OCT-4, NANOG, and SOX2 that can act as super-enhancers (SE), cluster of genes in non-cancerous, cancerous and metastatic PDAC cell lines.

1 Mar 2019

Scientists find clue to rapid human conversations in singing mice

Studying the songs of mice from the cloud forests of Costa Rica, researchers from New York University School of Medicine and The University of Texas at Austin have identified a brain circuit that might enable the high-speed back and forth of human conversation.

1 Mar 2019

Research shows how common fungus gets the flexibility to live in different host environments

The fungus Candida albicans is found in the gastrointestinal tract of about half of healthy adults with little if any effect, yet it also causes an oft-fatal blood infection among patients with compromised immune systems, including those with HIV/AIDS.

1 Mar 2019

Research reveals how metabolites can be used to inhibit epigenetic mechanisms and treat MS

Understanding and mitigating the role of epigenetics (environmental influences that trigger changes in gene expression) in disease development is a major goal of researchers.

28 Feb 2019

New clues to triggers of gut inflammation uncovered

New detail about what happens when a key cellular process is impaired in cells that are vital for a healthy gut have been uncovered by a wide-ranging analysis.

28 Feb 2019

Personalized therapy for aggressive brain cancer shows potential

Advances in genetics and genomics have taught us that every single tumor is different, and yet most standard therapies treat them all in the same way, limiting the effectiveness of treatments offered to many cancer patients.

28 Feb 2019

Breakthrough chromosome imaging could aid in development of new treatments

Chromosomes, each containing hundreds or thousands of genes, act like a detailed instruction manual for how cells should develop and behave.

28 Feb 2019

Johns Hopkins researchers find genetic cause of olfactory neuroblastoma

By sequencing the entire genomes of tumor cells from six people with a rare cancer of the nose and sinus cavity, Johns Hopkins researchers report they unexpectedly found the same genetic change¾one in a gene involved in muscle formation¾in five of the tumors.

28 Feb 2019

Newly discovered drug targets could pave way for esophageal cancer therapeutics

Blocking two molecular pathways that send signals inside cancer cells could stave off esophageal adenocarcinoma, the most common esophageal malignancy in the United States, according to new research out of Case Western Reserve University School of Medicine.

28 Feb 2019

Structure of human type 2 cannabinoid receptor revealed

A Chinese research team joined forces with Russian and U.S. biologists to obtain the crystal structure of the human type 2 cannabinoid receptor.

28 Feb 2019

Scientists identify how cells make choice between various mechanisms to repair DNA

When DNA in the cell nucleus gets damaged, our cells can resort to a variety of repair mechanisms. A recent study published in 'Nature Cell Biology', to which scientists from Helmholtz Zentrum Muenchen made major contributions, elucidates the molecular basis by which a cell makes the choice between these repair mechanisms.

28 Feb 2019

New strategy may alleviate motor disorders in Parkinson's patients

Scientists of the German Center for Neurodegenerative Diseases and the University Medical Center Goettingen have been able to alleviate motor disorders in mice that resemble those seen in Parkinson's patients.

28 Feb 2019

Study finds specific mechanism that protects cells from natural DNA errors

Researchers from the University of Copenhagen have identified a specific mechanism that protects our cells from natural DNA errors - an 'enemy within' - which could permanently damage our genetic code and lead to diseases such as cancer.

27 Feb 2019

Experimental treatment offers hope to restore cells damaged in Parkinson's disease

A pioneering clinical trials program that delivered an experimental treatment directly to the brain offers hope that it may be possible to restore the cells damaged in Parkinson's disease.

27 Feb 2019

Researchers discover new mechanism of bone growth

In a paper published in the journal Nature, an international research team led by researchers at Karolinska Institutet in Sweden report that bone growth in mice takes place in accordance with the same principles as when new cells are constantly produced in blood, skin and other tissue.

27 Feb 2019

Pioneering trial offers hope for patients with Parkinson’s disease

In a pioneering new clinical trial, researchers have succeeded in delivering a cell-restoring drug directly to the brains of patients with Parkinson’s disease.

27 Feb 2019

New test could be a ‘game changer’ in the treatment of chronic lymphocytic leukemia

The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukemia has been developed at Cardiff University. The technology could guide doctors’ decisions on which drugs to give to patients.

27 Feb 2019