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Researchers outline targeted therapeutic strategy for triple-negative breast cancer

New findings put forth by the University of Maryland Fischell Department of Bioengineering and researchers from four other academic institutions outline a targeted therapeutic strategy to treat triple-negative breast cancer - a potential first for the particularly aggressive form of breast cancer.

26 Feb 2019

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

Scientists at the University of British Columbia have discovered a new protein "switch" that could stop the progression of blood-poisoning, or sepsis, and increase the chances of surviving the life-threatening disease.

26 Feb 2019

'Chromosome scanner' that protects against cancer identified

In a new study, researchers from the University of Copenhagen have identified one of the main mechanisms behind the repair of serious damage to the human DNA. A 'scanner' inside the cells decides whether or not so-called flawless DNA repair, which protects against cancer, is launched.

26 Feb 2019

Scientists report new and improved method to detect chemical modifications to DNA

Ludwig Cancer Research scientists report in the current issue of Nature Biotechnology a new and improved method to detect chemical modifications to DNA.

26 Feb 2019

Immunologists uncover the immune system's unknown messenger

A novel messenger which alarms nearby cells when the immune system recognizes infections has been uncovered by immunologists from Aarhus University, Denmark. This knowledge will help fighting infections and autoimmune diseases.

26 Feb 2019

New microfluidic device can isolate individual cancer cells from blood samples

Researchers at the University of Illinois at Chicago and Queensland University of Technology of Australia, have developed a device that can isolate individual cancer cells from patient blood samples. The microfluidic device works by separating the various cell types found in blood by their size.

26 Feb 2019

Killer T cells may explain inability of immune cells to destroy cancer tumors

Scientists at the University of Virginia School of Medicine have discovered a defect in immune cells known as "killer T cells" that explains their inability to destroy cancer tumors. The researchers believe that repairing this defect could make the cells much better cancer killers.

26 Feb 2019

Scientists discover puzzle piece that plays key role in development of epilepsies

When an epileptic seizure occurs in the brain, the nerve cells lose their usual pattern and fire in a very fast rhythm. The cause is a complex interplay of various factors.

25 Feb 2019

FDA warns Total Thermal Imaging for illegally marketing unapproved thermography device

The U.S. Food and Drug Administration has issued a warning letter toTotal Thermal Imaging Inc., of La Mesa, California, and its president and co-owner, Linda Hayes, for illegally marketing and distributing an unapproved thermography device as a sole screening device for breast cancer and other diseases.

25 Feb 2019

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Although molecular-targeted drugs have been known to show high efficacy to lung cancer patients, they also have limitations due to acquiring resistance to the drug used.

25 Feb 2019

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

As the biomedical field races to develop therapies based on an individual's genetic makeup, a City of Hope scientist and his colleagues found that some commercial cell lines used for countless laboratory studies have mislabeled ancestry when it comes to minorities.

25 Feb 2019

Study findings can help develop new drugs for ischemia

Russian scientists investigated the role of opioid receptors in protecting the heart from coronary disease: the lack of its blood supply.

25 Feb 2019

Researchers discover origin of resistance to lung cancer

For treating cancer, drugs based on molecules known as tyrosine kinase inhibitors are sometimes used. One such tyrosine kinase inhibitor, called osimertinib, has been used to treat EGFR-mutated lung cancer with a certain degree of efficacy.

25 Feb 2019

Scientists identify cause of devastating pediatric brain disorder

An international effort led by physician-scientists at Rady Children's Institute for Genomic Medicine, in collaboration with a team at the Montreal Children's Hospital of the McGill University Health Centre, has identified the cause of a devastating pediatric brain disorder paving the way for the first step in developing potential therapies for this rare neurodegenerative condition.

25 Feb 2019

Fat cells exhibit circadian rhythms affecting critical metabolic functions, study finds

Fat cells in the human body have their own internal clocks and exhibit circadian rhythms affecting critical metabolic functions, new research in the journal Scientific Reports, finds.

25 Feb 2019

Neuron-derived estrogen key to making memories

Estrogen in the brain is important to keep neurons communicating and memories being made, scientists report.

25 Feb 2019

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

Researchers have engineered "antibody-like" T cell receptors that can specifically stick to cells infected with cytomegalovirus, or CMV, a virus that causes lifelong infection in more than half of all adults by age 40.

23 Feb 2019

New technology platform digitally counts growth factors in single cells

Whether healthy or diseased, human cells exhibit behaviors and processes that are largely dictated by growth factor molecules, which bind to receptors on the cells. For example, growth factors tell the cells to divide, move, and when to die--a process known as apoptosis.

23 Feb 2019

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Drugs such as ibuprofen or aspirin that relieve pain and lower fever are among the most frequently used drugs worldwide. They are used above all for the treatment of inflammatory reactions. However, in spite of their indisputable effectiveness and frequent use, we do not yet fully understand the underlying mechanisms of these drugs.

23 Feb 2019

Study unravels genetic basis of hypertrophic cardiomyopathy cases in Finland

One third of hypertrophic cardiomyopathy cases in Finland are caused by one of the four major mutations, a new study from the University of Eastern Finland and Kuopio University Hospital shows.

23 Feb 2019

Cell News and Research

Researchers outline targeted therapeutic strategy for triple-negative breast cancer

New protein 'switch' could stop progression of blood-poisoning and increase chances of survival

'Chromosome scanner' that protects against cancer identified

Scientists report new and improved method to detect chemical modifications to DNA

Immunologists uncover the immune system's unknown messenger

New microfluidic device can isolate individual cancer cells from blood samples

Killer T cells may explain inability of immune cells to destroy cancer tumors

Scientists discover puzzle piece that plays key role in development of epilepsies

FDA warns Total Thermal Imaging for illegally marketing unapproved thermography device

New research finds how cancer cells acquire resistance to molecular-targeted drugs

Lack of diversity in cell lines does not allow minorities to reap the benefits of precision medicine

Study findings can help develop new drugs for ischemia

Researchers discover origin of resistance to lung cancer

Scientists identify cause of devastating pediatric brain disorder

Fat cells exhibit circadian rhythms affecting critical metabolic functions, study finds

Neuron-derived estrogen key to making memories

Researchers engineer 'antibody-like' T cell receptors to combat deadly virus

New technology platform digitally counts growth factors in single cells

Researchers develop highly sensitive cell model to study complex effects of anti-inflammatory drugs

Study unravels genetic basis of hypertrophic cardiomyopathy cases in Finland

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