Laboratory News and Research

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Genoptix signs multi-year licensing agreement with HistoRx for AQUA technology

Genoptix, Inc., a specialized laboratory service provider, and HistoRx, Inc. (privately held), a diagnostics company, today announced a multi-year licensing agreement for AQUA® technology and several diagnostic assays based on it.

19 Feb 2010

BioCrossroads' Indiana Seed Fund invests $400,000 in Bioscience Vaccines

BioCrossroads' Indiana Seed Fund has invested in Bioscience Vaccines, Inc. to accelerate the development of biologic materials, which may boost the effectiveness of a wide range of life-saving vaccines.

19 Feb 2010

Kinesin protein motor shuttles cargo within cells and helps cells divide by rocking like a seesaw

Life's smallest motor, a protein that shuttles cargo within cells and helps cells divide, does so by rocking up and down like a seesaw, according to research conducted by scientists at the U.S. Department of Energy's Lawrence Berkeley National Laboratory and Brandeis University.

19 Feb 2010

Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

A new study of mutations in cancer genomes shows how researchers can begin to distinguish the 'driver' mutations that push cells towards cancer from the 'passenger' mutations that are a by-product of cancer cell development. The study also shows that at least one in nine genes can be removed without killing human cells.

19 Feb 2010

CMAJ study summarizes risk factors for severe outcome among patients admitted to hospital with H1N1

A new study in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/cgi/doi/10.1503/cmaj.091823 of all patients in Canada admitted to hospital for H1N1 in the first five months of the outbreak summarizes the risk factors for a severe outcome (www.cmaj.ca). The H1N1 pandemic presents important learnings for clinicians and researchers and data on severe outcomes can help inform future treatment and prevention guidelines.

19 Feb 2010

Most genetic abnormalities shared across multiple cancers

An international team of researchers has created a genome-scale map of 26 different cancers, revealing more than 100 genomic sites where DNA from tumors is either missing or abnormally duplicated compared to normal tissues. The study, the largest of its kind, finds that most of these genetic abnormalities are not unique to one form of cancer, but are shared across multiple cancers. The work appears in the February 18 issue of the journal Nature.

19 Feb 2010

Benefits of wartime camaraderie extend far beyond the battlefield: Study of U.S. Civil War veterans

Veterans who served in military units characterized by a strong esprit de corps were much less likely decades later to die of a stroke or heart condition than veterans from less cohesive companies, two UCLA economists have found.

19 Feb 2010

FDA approves 53 new cancer indications between July 2005 and end of 2007

The U.S. Food and Drug Administration's Office of Oncology Drug Products approved more than 50 new indications for the use of oncology and hematology drugs and biologics between July 2005, when the office began reviewing marketing applications, and the end of 2007, according to a new agency study.

19 Feb 2010

Research shows natural compound in marine sponges reduces cancer cell motility

Investigators at Sanford-Burnham Medical Research Institute (Sanford-Burnham, formerly Burnham Institute for Medical Research) led by Kristiina Vuori, M.D., Ph.D., have discovered that the natural compound sceptrin, which is found in marine sponges, reduces cancer cell motility (movement) and has very low toxicity.

19 Feb 2010

UBC researcher finds improved uptake of highly active antiretroviral therapy

A comprehensive population-based study, conducted by the BC Centre for Excellence in HIV/AIDS (BC-CfE) and presented at the 17th Conference on Retroviruses and Opportunistic Infections in San Francisco, shows that expanded highly active antiretroviral therapy (HAART) coverage was associated with a 50% decrease in new yearly HIV infections among injection drug users.

19 Feb 2010

VARI researchers find ways to reverse resistance to sunitinib: Patients with ccRCC show positive response

Van Andel Research Institute researchers have found a way to reverse resistance to sunitinib, a treatment that is currently the first line of defense against clear cell renal cell carcinoma (ccRCC), a deadly form of kidney cancer. Most patients who show a positive response to sunitinib develop a resistance to the drug after one year of treatment.

19 Feb 2010

Report: Green tea catechins may protect against glaucoma and other common eye diseases

Scientists have confirmed that the healthful substances found in green tea - renowned for their powerful antioxidant and disease-fighting properties - do penetrate into tissues of the eye. Their new report, the first documenting how the lens, retina, and other eye tissues absorb these substances, raises the possibility that green tea may protect against glaucoma and other common eye diseases.

19 Feb 2010

Poor prescription practices among doctors may increase antibiotic resistance

A new paper in the February 17th edition of the journal Molecular Cell describes how exposure to low levels of antibiotics increases mutations in E. coli and Staphylococcus bacteria hundreds of times more than normal, making the creation of drug-resistant strains more likely.

19 Feb 2010

Gladstone MD receives Potamkin Prize for identifying new avenues in Alzheimer's research

Lennart Mucke, MD, Director of the Gladstone Institute of Neurological Disease (GIND), has been named a recipient of the American Academy of Neurology's prestigious Potamkin Prize.

19 Feb 2010

AltraVax acquires vaccine development technology package from Maxygen

AltraVax, Inc., a new, privately-held biopharmaceutical company, has acquired a vaccine development technology package from Maxygen, Inc. that gives AltraVax an exclusive license to develop vaccines for infectious diseases and is targeting influenza, a treatment for hepatitis B and HIV.

18 Feb 2010

West Pharmaceutical Services reports 19.9% growth in consolidated fourth-quarter sales

West Pharmaceutical Services, Inc. today announced its results for the fourth quarter and full year of 2009.

18 Feb 2010

IRA to offer Personal Genetic Health and Ancestry Testing to residents of Latin America

Pathway Genomics™ (www.PATHWAY.com), a privately held, venture-backed company today announced that the Instituto de Referencia Andino (IRA), a Clinical Laboratory and Division of Rochem Biocare will offer Personal Genetic Health and Ancestry Testing to residents of Latin America.

18 Feb 2010

ScienceWorksForUS reveals how Recovery Act science funding benefits their campuses and communities

On the first anniversary of the American Recovery and Reinvestment Act (ARRA) - the economic stimulus - the nation's research universities today provided nearly 100 examples of how a relatively small element of the measure is paying outsize short- and long-term dividends for the nation. Of the $787 billion contained in the ARRA, $21.5 billion is allocated for research and science infrastructure.

18 Feb 2010

LabCorp acquires partnership units from noncontrolling interest holder in Ontario, Canada joint venture

Laboratory Corporation of America® Holdings announced today that on February 8, 2010 it completed a transaction to acquire the partnership units from the holder of the noncontrolling interest in the Company’s Ontario, Canada joint venture in accordance with the terms of the joint venture’s partnership agreement.

18 Feb 2010

Signaling protein has key role in fighting bacterial infection and inflammation in intestinal tract: Study

A signaling protein that is key in orchestrating the body's overall immune response has an important localized role in fighting bacterial infection and inflammation in the intestinal tract, according to a study by UC San Diego School of Medicine investigators, published in the journal Cell Host and Microbe.

18 Feb 2010

Laboratory News and Research

Genoptix signs multi-year licensing agreement with HistoRx for AQUA technology

BioCrossroads' Indiana Seed Fund invests $400,000 in Bioscience Vaccines

Kinesin protein motor shuttles cargo within cells and helps cells divide by rocking like a seesaw

Cancer genomes: Distinguishing between 'driver' and 'passenger' mutations

CMAJ study summarizes risk factors for severe outcome among patients admitted to hospital with H1N1

Most genetic abnormalities shared across multiple cancers

Benefits of wartime camaraderie extend far beyond the battlefield: Study of U.S. Civil War veterans

FDA approves 53 new cancer indications between July 2005 and end of 2007

Research shows natural compound in marine sponges reduces cancer cell motility

UBC researcher finds improved uptake of highly active antiretroviral therapy

VARI researchers find ways to reverse resistance to sunitinib: Patients with ccRCC show positive response

Report: Green tea catechins may protect against glaucoma and other common eye diseases

Poor prescription practices among doctors may increase antibiotic resistance

Gladstone MD receives Potamkin Prize for identifying new avenues in Alzheimer's research

AltraVax acquires vaccine development technology package from Maxygen

West Pharmaceutical Services reports 19.9% growth in consolidated fourth-quarter sales

IRA to offer Personal Genetic Health and Ancestry Testing to residents of Latin America

ScienceWorksForUS reveals how Recovery Act science funding benefits their campuses and communities

LabCorp acquires partnership units from noncontrolling interest holder in Ontario, Canada joint venture

Signaling protein has key role in fighting bacterial infection and inflammation in intestinal tract: Study

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