Biochemistry News and Research

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Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

My research lab studies several classes of systems. We are mostly interested in looking at large protein assemblies to understand their structure, dynamics and how their properties relate to their malfunction in disease.

From Bruker BioSpin Group 21 Sep 2016

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

In reading, a bookmark tells where you stopped. Cells use bookmarks too, specific proteins that help the cell remember what collection of genes needs to be turned on again after the brief halt of gene expression during cell division.

20 Sep 2016

Researchers discover gene variants linked to thoracic aortic dissections

On Super Bowl Sunday, Tina Wilkins was relaxing in her recliner while she chatted on the phone with her mother and waited for the game to begin. She had recently lost 63 pounds and was in better shape than she had been in years.

20 Sep 2016

Desalination can increase prevalence of inadequate iodine intake

Hebrew University study suggests that desalination can dramatically increase the prevalence of inadequate iodine intake.

19 Sep 2016

Food intolerance testing: an interview with Dr Gill Hart

Food intolerances are caused by adverse reactions to food or drink ingredients in your body. These are very different to food allergies. It is estimated that up to forty-five percent of the population suffers from food intolerances.

15 Sep 2016

Chemists develop one-step solution to make precursors for synthesis of drugs

A one-step solution to make nitrogen-laden molecular precursors for the preparation of drugs and other bioactive molecules has been discovered by researchers at Rice University, the University of Texas Southwestern Medical Center and Brigham Young University.

13 Sep 2016

Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Genome-wide studies of fission yeast (Schizosaccharomyces pombe) suggest that the evolutionary conserved enzyme Pfh1 helicase facilitates DNA synthesis by tracking along with the replication apparatus, promoting intact DNA synthesis at hard-to-replicate sites and consequently suppressing DNA damage. The findings are published in PLOS Genetics.

12 Sep 2016

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

As health departments around the U.S. boost efforts to combat Zika, scientists are working on new ways to kill the mosquitoes that carry the virus. One approach involves understanding the molecular mechanisms that keep the bugs alive so we can then undermine them.

9 Sep 2016

Scientists discover potential new genetic causes for intellectual disability

An international group of researchers has for the first time identified a set of 30 inherited recessive genes that play a role in intellectual disability (ID), a neurodevelopmental disorder that, according to the Centers for Disease Control, affects as many as 213 million people around the world.

9 Sep 2016

Mathematical model explains molecular events linked to learning and memory formation

A team of researchers has built a mathematical model that describes the molecular events associated with the beginning stage of learning and memory formation in the human brain.

9 Sep 2016

International conference on longevity to be held in Brussels for 3 days

The Eurosymposium on Healthy Ageing is an international event that provides a unique opportunity for researchers, government officials, biotech executives, entrepreneurs, and non-governmental institutions from around the world to meet, network, and forge new scientific collaborations.

9 Sep 2016

Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Groundbreaking research from the University of Alberta has identified the structure of the infectious prion protein, the cause of "mad cow disease" or BSE, chronic wasting disease in deer and elk and Creutzfeldt-Jakob disease in humans, which has long remained a mystery.

8 Sep 2016

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

In research published online today in Science, a team of scientists describe a new therapeutic strategy to target a hidden Achilles' heel shared by all known types of Ebola virus.

8 Sep 2016

Research could pave way for more effective and safer anti-epilepsy drugs

Columbia University Medical Center researchers have discovered how a new epilepsy drug works, which may lead the way to even more effective and safer medications.

8 Sep 2016

Interactions between rare and common genetic variants may contribute to craniosynostosis

During the first year of life, the human brain doubles in size, and continues growing through adolescence.

8 Sep 2016

Researchers use unique computational approach to identify promising drug leads for heart diseases

Using a unique computational approach to rapidly sample, in millisecond time intervals, proteins in their natural state of gyrating, bobbing, and weaving, a research team from UC San Diego and Monash University in Australia has identified promising drug leads that may selectively combat heart disease, from arrhythmias to cardiac failure.

6 Sep 2016

HIF-2 inhibitors could be promising target to combat kidney cancer

A new class of drugs called HIF-2 inhibitors is more effective and better tolerated than the standard of care drug sunitinib in treating kidney cancer, researchers with the Kidney Cancer Program at Harold C. Simmons Comprehensive Cancer Center have found.

6 Sep 2016

Researchers describe how genetic mutations cause unnamed neurological disorder

In rare cases -- for instance, among siblings in two families from Pakistan and Oman described in a new study -- children have been born with an unnamed neurological disorder.

6 Sep 2016

New discovery offers way to develop vaccine against highly infectious bacteria

Biochemists at the University of California San Diego have uncovered patterns in the outer protein coat of group A Streptococcus that could finally lead to a vaccine against this highly infectious bacteria--responsible for more than 500,000 deaths a year, including toxic shock syndrome and necrotizing fasciitis or "flesh-eating disease."

5 Sep 2016

Research aims to understand how cell designs length, pattern of heparan sulphate chains

Heparan sulphate occurs as carbohydrate chains which are very important for human body cells both for normal foetal development and during the course of various diseases.

2 Sep 2016

Biochemistry News and Research

Solid-state NMR in structural biology: an interview with Professor Tatyana Polenova

De-bookmarking could be key to better reprogramming of fibroblasts into iPS cells

Researchers discover gene variants linked to thoracic aortic dissections

Desalination can increase prevalence of inadequate iodine intake

Food intolerance testing: an interview with Dr Gill Hart

Chemists develop one-step solution to make precursors for synthesis of drugs

Genome-wide studies reveal evolutionary conserved enzyme facilitates DNA replication

Scientists reveal new structural insights on key protein from mosquitoes linked to spread of Zika

Scientists discover potential new genetic causes for intellectual disability

Mathematical model explains molecular events linked to learning and memory formation

International conference on longevity to be held in Brussels for 3 days

Groundbreaking research unravels structure of infectious prions that cause mad cow disease

Novel Trojan Horse antibody strategy may target Ebola's Achilles' heel

Research could pave way for more effective and safer anti-epilepsy drugs

Interactions between rare and common genetic variants may contribute to craniosynostosis

Researchers use unique computational approach to identify promising drug leads for heart diseases

HIF-2 inhibitors could be promising target to combat kidney cancer

Researchers describe how genetic mutations cause unnamed neurological disorder

New discovery offers way to develop vaccine against highly infectious bacteria

Research aims to understand how cell designs length, pattern of heparan sulphate chains

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