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Cardiologists succeed in localized cooling of the heart to limit damage from heart attack

Cardiologists at the Catharina hospital in Eindhoven have succeeded in the localized cooling of the heart during a heart attack, a world first. By cooling part of the heart prior to and following angioplasty, the cardiologists believe that the damage from a heart attack can be limited.

12 Jan 2018

Researchers discover new warning system in the immune defense

Researchers at Linköping University in Sweden have discovered a previously unknown warning system that contributes to the body's immune system. Mitochondria in the white blood cells secrete a web of DNA fibers that raises the alarm.

12 Jan 2018

Global study on stroke prevention in high-risk AF patients

The largest global clinical study on the best-possible therapy for patients with atrial fibrillation at high risk of having a stroke and at increased risk of bleeding is starting at the German Centre for Cardiovascular Research.

12 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

The field of immunotherapy - the harnessing of patients' own immune systems to fend off cancer - is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy.

12 Jan 2018

Genetic analysis can enhance outcomes of depression treatment

The failure of drugs such as SSRIs, used to treat depression, can be a result of genetic variations in patients.

12 Jan 2018

‘Nudging’ techniques could increase parents’ intentions for cord blood donations

It contains potentially lifesaving stem cells that can treat a host of blood-based cancers and other diseases. Yet the blood found in newborns' umbilical cords is almost always discarded as medical waste, rather than banked for future needs.

12 Jan 2018

Humanitarian program decreases stress hormone levels in adolescents affected by war

A new study shows that a humanitarian program to improve the mental health of adolescents affected by the Syrian war has decreased levels of cortisol (a hormone associated with stress) in participants by a third.

12 Jan 2018

Novel polygenic hazard score captures age variations of aggressive prostate cancer

An international team, led by researchers at the University of California San Diego School of Medicine, has developed and validated a genetic tool for predicting age of onset of aggressive prostate cancer, a disease that kills more than 26,000 American men annually.

12 Jan 2018

People with family history of heart attack may be more at risk

The president of the American Heart Association, Dr John Warner, had a minor heart attack recently during a scientific conference held in California.

12 Jan 2018

New analysis highlights need for protective therapy to reduce risk of repeat heart attacks

AstraZeneca announced today the publication of a new analysis from an ongoing real-world quality registry that suggests the risk of experiencing a repeat heart attack (also known as a myocardial infarction or MI) from occlusions in non-stented arteries is twice as high as the risk stemming from the initially stented artery following a first heart attack.

12 Jan 2018

Insilico Medicine develops new deep-learning based hematological human aging clock

Today, Insilico Medicine, Inc., a Baltimore-based company specializing in the application of artificial intelligence for drug discovery, biomarker development and aging research, announced a publication of a research paper titled "Population-specific biomarkers of human aging: a big data study using South Korean, Canadian and Eastern-European patient populations" in The Journal of Gerontology.

11 Jan 2018

Researchers discover new weapon to combat tuberculosis

Tuberculosis (TB), an infectious disease which attacks the lungs, claims someone's life every 20 seconds and 1.5 million lives worldwide every year.

11 Jan 2018

New study shows how the immune system regulates gut fungal population

Immune cells that process food and bacterial antigens in the intestines control the intestinal population of fungi, according to a new study from Weill Cornell Medicine scientists.

11 Jan 2018

Unhealthy diet makes the body's defenses more aggressive in the long term

The immune system reacts similarly to a high fat and high-calorie diet as to a bacterial infection. This is shown by a recent study led by the University of Bonn.

11 Jan 2018

Elevated levels of inflammation marker linked to lower muscle mass

Elevated levels of the inflammation marker CRP in the blood is an underlying cause of the loss of muscle mass in elderly persons, as shown by a new study from örebro University and University of Nottingham.

11 Jan 2018

Metabolic Syndrome could make it harder for older adults to respond to antidepressant therapy

Researchers suspect that having Metabolic Syndrome makes it harder for older adults to respond to therapies for depression.

11 Jan 2018

Implanted robotic system stimulates tissue growth in stunted organs

An implanted, programmable medical robot can gradually lengthen tubular organs by applying traction forces -- stimulating tissue growth in stunted organs without interfering with organ function or causing apparent discomfort, report researchers at Boston Children's Hospital.

11 Jan 2018

Researchers create ‘protocells’ for delivering drugs to deepest tumor regions

Despite herculean efforts, cancer remains a formidable disease, with each malignant subtype responding differently to therapeutics.

11 Jan 2018

Human cardiac-muscle patches improve recovery from heart attack injury

Large, human cardiac-muscle patches created in the lab have been tested, for the first time, on large animals in a heart attack model. This clinically relevant approach showed that the patches significantly improved recovery from heart attack injury.

11 Jan 2018

Blood News and Research

Cardiologists succeed in localized cooling of the heart to limit damage from heart attack

Researchers discover new warning system in the immune defense

Global study on stroke prevention in high-risk AF patients

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

Prostate cancer’s gene-determined ‘immune landscape’ dictates tumor progression

Genetic analysis can enhance outcomes of depression treatment

‘Nudging’ techniques could increase parents’ intentions for cord blood donations

Humanitarian program decreases stress hormone levels in adolescents affected by war

Novel polygenic hazard score captures age variations of aggressive prostate cancer

People with family history of heart attack may be more at risk

New analysis highlights need for protective therapy to reduce risk of repeat heart attacks

Insilico Medicine develops new deep-learning based hematological human aging clock

Researchers discover new weapon to combat tuberculosis

New study shows how the immune system regulates gut fungal population

Unhealthy diet makes the body's defenses more aggressive in the long term

Elevated levels of inflammation marker linked to lower muscle mass

Metabolic Syndrome could make it harder for older adults to respond to antidepressant therapy

Implanted robotic system stimulates tissue growth in stunted organs

Researchers create ‘protocells’ for delivering drugs to deepest tumor regions

Human cardiac-muscle patches improve recovery from heart attack injury

Industry Focus eBook - Forensics & toxicology (2nd edition) eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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