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Discovery of key protein’s structure may help improve drug design

Scientists at The Scripps Research Institute have peered deep into the heart of a key protein used in drug design and discovered dynamic structural features that may lead to new ways to target diseases.

29 Dec 2017

Proteasome inhibitor treatment can lead to cardiovascular problems in multiple myeloma patients

The proteasome inhibitor carfilzomib has taken on an increasing role in the treatment of multiple myeloma, but new research from the Abramson Cancer Center of the University of Pennsylvania shows the therapy comes with the risk of cardiovascular problems in a higher than expected percentage of patients.

28 Dec 2017

Innovative skin patch to reduce bulging tummy fats could help address obesity problem

It combines a new way to deliver drugs, via a micro-needle patch, with drugs that are known to turn energy-storing white fat into energy-burning brown fat.

28 Dec 2017

Sickle cell patients, families and doctors face a ‘fight for everything’

The day before his 30th birthday, Marqus Valentine was in a panic. "I was so scared for midnight to come rolling around because subconsciously I was like, 'This is it. Tomorrow’s my last day on Earth,'" he said.

27 Dec 2017

Study: Noninvasive brainwave technology reduces post-traumatic symptoms in military personnel

A noninvasive brainwave mirroring technology significantly reduced symptoms of post-traumatic stress in military personnel in a pilot study conducted at Wake Forest Baptist Medical Center.

27 Dec 2017

Study highlights pernicious effect of obesity on blood-making stem cells

New research published in the Journal of Experimental Medicine highlights the pernicious effect of obesity on the long-term health of blood-making stem cells (hematopoietic stem cells).

27 Dec 2017

Researchers discover internal body scales that regulate fat mass

Researchers at Sahlgrenska Academy, University of Gothenburg, Sweden, have found evidence for the existence of an internal body weight sensing system.

27 Dec 2017

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

To date, the molecular basis of pulmonary fibrosis has been poorly understood. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim have now shown that reduced activity of the transcription factor FoxO3 plays a key role in the development of the disease.

26 Dec 2017

$Calcium, vitamin D supplements may not protect older adults against hip fractures$

Calcium, vitamin D supplements may not protect older adults against hip fractures

Supplements containing calcium, vitamin D or both did not appear to protect against hip fracture and other bone breaks in older adults.

26 Dec 2017

Study explores link between childhood blood lead levels and risk for criminal behavior

Researchers found no consistent association between childhood lead exposure and adult criminal behavior in New Zealand where low socioeconomic status, which confuses the association in settings with socioeconomic disparities, is less of a factor.

26 Dec 2017

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Novartis announced today that the US Food and Drug Administration (FDA) approved the inclusion of Treatment-free Remission (TFR) data in the Tasigna® (nilotinib) US product label.

26 Dec 2017

Researchers find more precise, neuroprotective approach to fix MS-damaged nerves

Gene expression in specific cells and in specific regions can provide a more precise, neuroprotective approach than traditional treatments for neurological diseases.

26 Dec 2017

Study opens up new avenues for stopping calcific aortic valve disease

The diminutive size of our aortic valve -- just shy of a quarter -- belies its essential role in pushing oxygen-rich blood from the heart into the aorta, our body's largest vessel, and from there to all other organs. Yet for decades, researchers have focused less on damaged valves than on atherosclerosis, the gradual hardening of the blood vessels themselves.

26 Dec 2017

International researchers find valuable clues for developing robust therapeutic agents against IBDs

Our immune system protects our bodies from numerous pathogenic microbes and toxins in the environment. The system comprises innate (non-specific) and adaptive (acquired) immunity.

26 Dec 2017

Study provides ‘big picture’ of cognitive flexibility

A healthy brain can quickly switch its focus from the large shapes to the individual parts that make up the bigger pictures.

22 Dec 2017

Researchers create visual database of metabolites from blood samples

Researchers in Japan have created a database of metabolites from blood samples collected from over 5,000 Japanese volunteers, making it freely available online as a valuable resource for researchers around the world.

22 Dec 2017

Probiotics may offer protection against depression linked to unhealthy lifestyle

New research suggests that the micro-organisms known as probiotics, which are normally providing health benefits in the intestines, also have an affect on the brain, or as an actual study at Aarhus University has shown; protect against depression.

22 Dec 2017

Hormone therapy combination may improve metabolism without increasing risk of reproductive cancer

Treating ovariectomized mice with a combination of conjugated estrogens and the drug bazedoxifene triggers the expression of genes that improve metabolism and prevent weight gain - without stimulating the uterus and increasing risks of reproductive cancer, a new study suggests.

22 Dec 2017

Sahlgrenska University Hospital becomes first Swedish site to take part in early pancreatic cancer detection study

Immunovia AB today announced that Sahlgrenska University Hospital is the first Swedish site to be part of PanFAM-1, a multicenter prospective validation study for the early diagnosis in familiar pancreatic cancer (FPC) high risk individuals.

22 Dec 2017

Study finds new marker to detect fatal breast cancer

A new study conducted at the University College London, UK, found a new marker that has the capacity to help diagnose fatal breast cancer up to one year earlier than existing methods.

22 Dec 2017

Blood News and Research

Discovery of key protein’s structure may help improve drug design

Proteasome inhibitor treatment can lead to cardiovascular problems in multiple myeloma patients

Innovative skin patch to reduce bulging tummy fats could help address obesity problem

Sickle cell patients, families and doctors face a ‘fight for everything’

Study: Noninvasive brainwave technology reduces post-traumatic symptoms in military personnel

Study highlights pernicious effect of obesity on blood-making stem cells

Researchers discover internal body scales that regulate fat mass

Reduced activity of transcription factor plays key role in triggering pulmonary fibrosis

Calcium, vitamin D supplements may not protect older adults against hip fractures

Study explores link between childhood blood lead levels and risk for criminal behavior

Novartis announces FDA approval of its first and only CML therapy with TFR data in product label

Researchers find more precise, neuroprotective approach to fix MS-damaged nerves

Study opens up new avenues for stopping calcific aortic valve disease

International researchers find valuable clues for developing robust therapeutic agents against IBDs

Study provides ‘big picture’ of cognitive flexibility

Researchers create visual database of metabolites from blood samples

Probiotics may offer protection against depression linked to unhealthy lifestyle

Hormone therapy combination may improve metabolism without increasing risk of reproductive cancer

Sahlgrenska University Hospital becomes first Swedish site to take part in early pancreatic cancer detection study

Study finds new marker to detect fatal breast cancer

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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