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New approach links cancer cell metabolism with poor clinical outcome

Identifying gene mutations in cancer patients to predict clinical outcome has been the cornerstone of cancer research for nearly three decades, but now researchers at the Kimmel Cancer Center at Jefferson have invented a new approach that instead links cancer cell metabolism with poor clinical outcome. This approach can now be applied to virtually any type of human cancer cell.

15 Apr 2011

Researchers develop Short-CGH method for preimplantation genetic screening

A Short Comparative Genomic Hybridisation method has been developed to carry out preimplantation genetic screening by analysing all chromosomes and transferring selected embryos to the recipient uterus in the same in vitro fertilisation cycle. This eliminates the need to freeze them.

15 Apr 2011

Elsevier introduces new online research tool

Elsevier, the leading publisher of scientific, technical and medical information products and services, today announced the launch of Methods Navigator. This online research tool enables life scientists to search, access and apply the right method for their research, saving time and producing high-quality results.

15 Apr 2011

Sea squirt study unravels complex mechanisms underlying heart defects

Each year in the U.S., approximately 40,000 babies are born with a heart defect. Without the proper diagnosis and treatment, many of these babies would die before their first birthday, according to Dr. Scott Klewer, a cardiologist at the UA's College of Medicine.

12 Apr 2011

Scientists develop new method to detect virus presence in cells

Scientists at the Naval Research Laboratory Center for Bio-Molecular Science and Engineering have developed a method to detect the presence of viruses in cells and to study their growth.

12 Apr 2011

Cellix expands European distribution network with Tebu-bio

Cellix are pleased to announce the signing of a distribution agreement with tebu-bio SAS. tebu-bio has a well-established pan-European presence, recognised by the international scientific community with local offices in France, Germany, Belgium, the Netherlands, Italy, Denmark, Portugal, Spain and the UK.

11 Apr 2011

Scientists identify new treatment to combat PFAPA syndrome in children

A preliminary study conducted by a team at the National Institutes of Health has identified a promising new treatment in children for the most common form of a rare disorder.

11 Apr 2011

Mammal muscle turned into biological raw material for new limb

Move over, newts and salamanders. The mouse may join you as the only animal that can re-grow their own severed limbs. Researchers are reporting that a simple chemical cocktail can coax mouse muscle fibers to become the kinds of cells found in the first stages of a regenerating limb. Their study, the first demonstration that mammal muscle can be turned into the biological raw material for a new limb, appears in the journal ACS Chemical Biology.

8 Apr 2011

ASBMB honors Stanford professor with DeLano Award for Computational Biosciences

Stanford University professor Axel T. Brunger has been named the winner of the American Society for Biochemistry and Molecular Biology's inaugural DeLano Award for Computational Biosciences. Brunger will present his award lecture, titled "Towards Structural Biology with Single Molecules" at 9:03 a.m. on Wednesday, April 13, at the Experimental Biology 2011 conference at the Walter E. Washington Convention Center in Washington, D.C.

8 Apr 2011

New publication on therapeutic hypothermia and temperature management

The successful use and evaluation of therapeutic hypothermia to improve survival and reduce the risk of neurological consequences following an out-of-hospital heart attack are explored in the premier issue of Therapeutic Hypothermia and Temperature Management, a new quarterly peer-reviewed journal published by Mary Ann Liebert, Inc.

8 Apr 2011

Novel strategy to build molecular probes may lead to development of new cancer drugs

Chemical engineers at UC Santa Barbara expect that their new process to create molecular probes may eventually result in the development of new drugs to treat cancer and other illnesses.

7 Apr 2011

Scientists reveal unknown role of cilia protein IFT88 in mitosis

Researchers at the University of Massachusetts Medical School have described a previously unknown role for the cilia protein IFT88 in mitosis, the process by which a dividing cell separates its chromosomes containing the cell's DNA into two identical sets of new daughter cells.

5 Apr 2011

Stand Up to Cancer awards UNC Lineberger scientist with 13 Innovative Research Grants

Angelique Whitehurst, PhD, assistant professor of pharmacology and a member of UNC Lineberger Comprehensive Cancer Center, has been awarded one of 13 Innovative Research Grants from Stand Up to Cancer, the scientific partner of the American Association of Cancer Research.

5 Apr 2011

CPRIT awards $12.6M grant to Gulf Coast Consortia to develop new cancer treatments

The Gulf Coast Consortia has been awarded a grant of more than $12.6 million from the Cancer Prevention Research Institute of Texas to launch a collaborative program that brings together researchers with the common purpose of developing new cancer treatments.

1 Apr 2011

3D experiments reveal MSCs have potential to produce different cell types

A type of adult stem cell is now proving itself more versatile for research and therapies thanks to revolutionary 3D experiments. These cells have already shown great promise for repairing damaged bone and cartilage but until now have been fairly limited in the types of cells they can form in the laboratory.

31 Mar 2011

Molecular pharmacologist receives AACR Award for cancer research

Susan Band Horwitz, Ph.D., will receive the Eighth Annual AACR Award for Lifetime Achievement in Cancer Research. Horwitz conducted pioneering research by discovering the mechanism of action of the chemotherapeutic drug paclitaxel, which prompted the development of this drug as an important therapy for many common solid tumors, including ovarian, breast, and lung carcinomas.

28 Mar 2011

Research outlines how cilia disease gene products regulate early cilium formation

An international collaboration jointly led by University College Dublin, University of Alabama and Simon Fraser University, British Columbia has outlined in the Journal of Cell Biology how cilia disease gene products regulate important aspects of early cilium formation and the integrity of the ciliary transport gate.

21 Mar 2011

Scientists discover enzyme family that plays a crucial role in regulating cell motility

Researchers at Albert Einstein College of Medicine of Yeshiva University have discovered that members of an enzyme family found in humans and throughout the plant and animal kingdoms play a crucial role in regulating cell motility. Their findings suggest an entirely new strategy for treating conditions ranging from diabetic ulcers to metastatic cancer.

19 Mar 2011

New video content about fungal cell biology

A recent special edition of the journal Fungal Biology Reviews, published by Elsevier, on behalf of the British Mycological Society, features a total of 76 videos which together comprise the most comprehensive collection of fungal cell biology movies ever published.

17 Mar 2011

New research: Fzd9 receptor can stimulate bone formation

New research shows that the Wnt receptor Frizzled-9 promotes bone formation, providing a potential new target for the treatment of osteoporosis. The study appears online on March 14 in The Journal of Cell Biology.

15 Mar 2011