Glycolysis News and Research

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Glycolysis is a series of reactions that helpextract energy from glucose. This is an ancient pathway of metabolism that is present in the majority of living organisms today. It is the foundation of both aerobic and anaerobic cellular respiration. It takes place in the cytosol of a cell and is the foundation of both aerobic and anaerobic cellular respiration.

Targeting metabolic function of breast cancer may help combat disease

How does a cancer cell burn calories? New research from Thomas Jefferson University shows that breast cancer cells rely on a different process for turning fuel into energy than normal cells.

28 Nov 2016

Epigenetic enzyme plays key role in maintaining metabolic properties of brown fat, research shows

In mammals, three types of adipose tissues exist. White adipocytes are mainly located in the abdominal and subcutaneous areas of the body and highly adapted to store excess energy.

31 Oct 2016

Research shows metabolism of macrophages can be attuned to prevent spread of cancer

Scientists at VIB and KU Leuven have discovered a crucial factor in the spread of cancer. A team led by professor Massimiliano Mazzone has demonstrated that the metabolism of macrophages, a particular type of white blood cell, can be attuned to prevent the spread of cancer.

20 Oct 2016

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

A drink developed for soldiers to generate energy from ketones rather than carbs or fat allowed highly trained cyclists to add up to 400 meters of distance to their workouts, a UK-led study reports July 27 in Cell Metabolism.

27 Jul 2016

Scientists identify timing of major metabolic shift in developing neurons

Our brains can survive only for a few minutes without oxygen. Salk Institute researchers have now identified the timing of a dramatic metabolic shift in developing neurons, which makes them become dependent on oxygen as a source of energy.

13 Jul 2016

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Cancerous tumors must be fed. Their unregulated growth requires a steady stream of blood flow and nutrients. Thus, one way that researchers have tried to wipe out cancer is to target cells undergoing the metabolic shifts that enable a tumor's rapid growth.

7 Jul 2016

Scientists reveal metabolic reasons why low calorie diets may lead to longer life

Overeating can lead to health issues that can shorten one's life, such as obesity, diabetes and heart disease.

30 Jun 2016

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Researchers have identified a new signaling pathway that helps cancer cells cope with the lack of oxygen found inside tumors. These are the results of a study published in Nature Cell Biology on June 20, and led by researchers at NYU Langone Medical Center and its Laura and Isaac Perlmutter Cancer Center, Princess Margaret Cancer Center, the University of Toronto, Harvard Medical School and Oxford University.

21 Jun 2016

Diet modification could help improve quality of life in women with ovarian cancer

New research conducted at the University of Alabama at Birmingham has shown that a particular type of diet could help women with ovarian cancer to lose weight and improve their quality of life and cancer-related measures.

16 Jun 2016

University of Arizona selects Cubresa’s NuPET scanner for cancer research

Cubresa Inc., a medical imaging company that develops and markets molecular imaging systems, today announced that their compact PET scanner called NuPET™ for simultaneous preclinical PET (Positron Emission Tomography) and MRI (Magnetic Resonance Imaging) has been selected by the University of Arizona (UA).

From Cubresa Inc. 1 Jun 2016

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

A team of researchers at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine recently discovered a novel, non-toxic approach to treating a wide variety of cancers.

19 May 2016

Researchers report tumors can continue to grow even without supply of new blood vessels

When medication is used to shut off the oxygen supply to tumor cells, the cells adapt their metabolism in the medium term -- by switching over to producing energy without oxygen. This observation by biomedical scientists at the University of Basel and University Hospital Basel could be used for treatments that can inhibit tumor growth in the long term, as the researchers report in the latest issue of the journal Cell Reports.

29 Apr 2016

Bacteria uses sensitive, nano-sized pump to transport magnesium

Researchers at UiO and NCMM have discovered that the system used by bacteria to transport magnesium is so sensitive that it can detect a pinch of magnesium salt in a swimming pool.

7 Apr 2016

PKM2 enzyme plays major role in early steps of wound healing

An enzyme involved in glucose metabolism in cells plays a major role in the early steps of wound healing, a finding that could lead to new therapeutic approaches for wound care, according to researchers at Georgia State University.

11 Mar 2016

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Using a new approach, scientists at The Scripps Research Institute and collaborating institutions have discovered a novel drug candidate that could be used to treat certain types of breast cancer, lung cancer and melanoma.

10 Mar 2016

Study provides critical insight into Warburg effect

PGK1, a glycolytic enzyme, has been found to play a role in coordinating cellular processes crucial to cancer metabolism and brain tumor formation, according to results published in today's online issue of Molecular Cell. The findings may lay the groundwork for improved approaches to diagnosis and treatment of glioblastoma and other cancers.

4 Mar 2016

Glycolysis News and Research

Further Reading

Targeting metabolic function of breast cancer may help combat disease

Epigenetic enzyme plays key role in maintaining metabolic properties of brown fat, research shows

Research shows metabolism of macrophages can be attuned to prevent spread of cancer

Single drink of nutritional ketone can alter metabolism to improve performance of cyclists

Scientists identify timing of major metabolic shift in developing neurons

Mitochondrial stress can trigger tumor-related metabolic shifts, study finds

Scientists reveal metabolic reasons why low calorie diets may lead to longer life

Breast cancer cells use new signaling pathway to cope with lack of oxygen levels inside tumors

Diet modification could help improve quality of life in women with ovarian cancer

University of Arizona selects Cubresa’s NuPET scanner for cancer research

Combining 2-DG with fenofibrate could provide non-toxic treatments for many cancers

Researchers report tumors can continue to grow even without supply of new blood vessels

Bacteria uses sensitive, nano-sized pump to transport magnesium

PKM2 enzyme plays major role in early steps of wound healing

Scientists discover novel drug candidate to treat breast cancer, lung cancer and melanoma

Study provides critical insight into Warburg effect

Findings suggest potential metabolic pathway against cancer

NS1 protein can be considered as vital target for development of new drugs to treat dengue: Study

Study shows link between impaired mitochondria, energy failure, and neuronal dysfunction

Diabetes drug 'suffocates' pancreatic cancer stem cells, new study finds

New Approach Methodologies, the 3Rs and Multimodal Imaging in Preclinical Research - eBook eBook

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