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UH Cleveland Medical Center explores novel treatments for uterine fibroids

Uterine fibroids, or uterine myomas, can cause symptoms that include unusually long and heavy menstrual flow, pain, enlarged uterus, pressure on the bladder and rectum, and uncomfortable intercourse.

19 Feb 2018

Major review suggests link between female sex hormones and allergies, asthma

Fluctuations in female sex hormones could play a role in the development of allergies and asthma, a major review of evidence suggests.

15 Feb 2018

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Cleveland Clinic researchers have published findings in Nature Communications on a new stem cell pathway that allows a highly aggressive form of breast cancer - triple-negative breast cancer - to thrive.

8 Feb 2018

Study uncovers potential targets for treatment of aggressive triple-negative breast cancers

As part of a breast-cancer diagnosis, doctors analyze the tumor to determine which therapies might best attack the malignancy.

2 Feb 2018

Imaging technique used to identify women at risk of premature labor

Ultrasound is traditionally used on pregnant women to study the anatomy, movement and blood flow of the developing fetus, but University of Illinois at Chicago nurse researchers are using the imaging technique to identify women who are at risk of giving birth prematurely.

27 Jan 2018

Sex steroid hormone fluctuations may have direct effects on eye physiology and AMD

Gender-based differences may influence several ocular conditions, suggesting that fluctuations in sex steroid homeostasis may have direct effects on eye physiology and the pathogenesis of conditions like Age-Related Macular Degeneration.

18 Jan 2018

"Baby brain" a real clinical entity finds study

Pregnant women are often forgetful and inattentive. This is called “baby brain” and has been recognized as a real entity by researchers now.

15 Jan 2018

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

AstraZeneca and Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has approved LYNPARZA (olaparib) for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting.

12 Jan 2018

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Researchers at the University of Cincinnati College of Medicine have identified for the first time that the estrogen receptor-binding protein MED1 is a critical mediator of HER2-driven breast cancer, identifying it as a potential therapeutic target.

9 Jan 2018

Women who conceive while using IUD more likely to have adverse perinatal outcomes

Women who conceive while using an intrauterine contraceptive device have a greater risk of preterm delivery, low birth weight babies, bacterial infections, or losing a fetus, according to researchers at Ben-Gurion University of the Negev and the Soroka University Medical Center.

8 Jan 2018

UVA scientists working to find end-around method to stop triple-negative breast cancer

So-called "triple-negative" breast cancer is a particularly aggressive and difficult-to-treat form. It accounts for only about 10 percent of breast cancer cases, but is responsible for about 25 percent of breast cancer fatalities.

20 Nov 2017

Mount Sinai researchers identify new therapeutic target for ER+ breast cancer

Researchers at the Icahn School of Medicine at Mount Sinai have identified a protein that can be targeted to suppress growth of a common type of breast cancer known as "estrogen receptor positive" (ER+), including ER+ cancers that are resistant to standard treatments.

17 Nov 2017

New study further validates use of vaginal progesterone to decrease risk of preterm birth

A new study published today - World Prematurity Day - in the American Journal of Obstetrics & Gynecology provides additional support for treatment with vaginal progesterone to reduce the risk of preterm birth, neonatal complications and infant death in pregnant women with a short cervix.

17 Nov 2017

Vaginal progesterone decreases the risk of premature birth in women with short cervix

A meta-analysis of placebo-controlled data published today indicates that vaginal progesterone reduces preterm birth and neonatal complications in women with a mid-trimester short cervix.

17 Nov 2017

Researchers find low levels of neuroactive steroid in both obese and anorexic women

Women at opposite extremes of the weight spectrum have low levels of the neuroactive steroid allopregnanolone, according to new research published in the journal Neuropsychopharmacology.

10 Nov 2017

Gene targets for triple negative breast cancers resistant to chemotherapy found

Researchers have finally found the genetic targets that could be used for treatment and development of new drugs in patients who are resistant to chemotherapy. These patients who are resistant to chemotherapy are most likely to have triple negative breast cancer which is the most aggressive form of breast cancer. The study appeared in the latest issue of the journal Cell Metabolism.

4 Oct 2017

Research uncovers potential targets for treatment of triple negative breast cancer

Research led by Dr. Carlos Arteaga, Director of the Harold C. Simmons Comprehensive Cancer Center, has identified potential targets for treatment of triple negative breast cancer, the most aggressive form of breast cancer.

3 Oct 2017

Pregnant women with endometriosis have greater risk for complications during pregnancy and delivery

A new meta-analysis shows that pregnant women with endometriosis are at greater risk for a host of complications during pregnancy and at delivery, including preterm birth and cesarean section. The study was published in the journal Fertility and Sterility.

13 Sep 2017

Researchers synthesizing new, first-in-class drug to stop growth of ER-positive breast cancer

Researchers at UT Health San Antonio and two partner institutions are developing a new, first-in-class agent that has stopped the growth of estrogen receptor-positive (ER-positive) breast cancer in its tracks.

30 Aug 2017

Scientists discover novel lineage-restricted stem cell in the mammary gland

One of the key questions in stem cell and cancer biology is to understand the cellular hierarchy governing tissue development and maintenance and the cancer cell of origin.

16 Aug 2017

Progesterone News and Research

UH Cleveland Medical Center explores novel treatments for uterine fibroids

Major review suggests link between female sex hormones and allergies, asthma

Study finds new stem cell pathway that allows triple-negative breast cancer to thrive

Study uncovers potential targets for treatment of aggressive triple-negative breast cancers

Imaging technique used to identify women at risk of premature labor

Sex steroid hormone fluctuations may have direct effects on eye physiology and AMD

"Baby brain" a real clinical entity finds study

U.S. FDA approves first drug for patients with germline BRCA-mutated metastatic breast cancer

UC scientists identify protein that acts as mediator of HER2-driven breast cancer

Women who conceive while using IUD more likely to have adverse perinatal outcomes

UVA scientists working to find end-around method to stop triple-negative breast cancer

Mount Sinai researchers identify new therapeutic target for ER+ breast cancer

New study further validates use of vaginal progesterone to decrease risk of preterm birth

Vaginal progesterone decreases the risk of premature birth in women with short cervix

Researchers find low levels of neuroactive steroid in both obese and anorexic women

Gene targets for triple negative breast cancers resistant to chemotherapy found

Research uncovers potential targets for treatment of triple negative breast cancer

Pregnant women with endometriosis have greater risk for complications during pregnancy and delivery

Researchers synthesizing new, first-in-class drug to stop growth of ER-positive breast cancer

Scientists discover novel lineage-restricted stem cell in the mammary gland

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From Discovery Biology to ELRIG Chair

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