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Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

By using specialized assays customized to detect specific receptor interactions, researchers from the Wellcome Sanger Institute in Cambridge UK find no evidence for direct binding of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein to a transmembrane glycoprotein known as basigin.

28 Jul 2020

Simple blood test may be a great advance for people with and at risk for Alzheimer's

A simple blood test for Alzheimer's would be a great advance for individuals with - and at risk for - the disease, families, doctors and researchers.

28 Jul 2020

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Precision medicine in cancer treatment uses genetic changes in the cancer cells to select the best therapies for individual patients.

28 Jul 2020

Population screening has potential to identify individuals at risk for inherited genetic conditions

In a new study published today in the journal Nature Medicine, researchers behind the Healthy Nevada Project® suggest that community-based genetic screening has the potential to efficiently identify individuals who may be at increased risk for three common inherited genetic conditions known to cause several forms of cancer and increased risk for heart disease or stroke.

27 Jul 2020

Study provides insight into evolution of amyloid-β oligomer with temporary salt crystals

Alzheimer's disease is the leading cause of dementia worldwide and a major cause of disability. Now, researchers at Osaka University and Hokkaido University have shown that repeated precipitation-dissolution events of salt crystals do occur even at low salt concentrations in nanoscales, and that it can accelerate the aggregation of the neurotoxic amyloid-β peptides implicated in its pathogenesis.

27 Jul 2020

Scientists develop COVID-19 test to detect neutralizing antibodies with high sensitivity, specificity

According to a study published in Nature Biotechnology, the sVNT is capable of detecting the functional neutralizing antibodies (NAbs) that can block the binding of the coronavirus spike protein to the angiotensin-converting enzyme 2 (ACE2) host receptor, which mimics the virus-host interaction.

25 Jul 2020

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

A HIGHLY accurate urine test which can rule out bladder cancer with a negative-predictive value of 99% using a hospital laboratory’s standard ELISA testing equipment is today being offered free to the NHS to help urologists clear the backlog of people waiting for a diagnosis and monitoring as a result of COVID-19 hospital closures.

25 Jul 2020

Exercise equipment in communal gyms have high levels of antibiotic-resistant bacteria

Research presented at ASM Microbe Online found that 43% of Staphylococcus bacteria found on exercise equipment in university gyms were ampicillin-resistant, with 73% of those isolates being resistant to multiple additional drugs.

24 Jul 2020

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest® bio-ADM®, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin. Blood levels of bio-ADM® reflect in real-time the functional status of the endothelium, the inner cell sheet of blood vessels.

24 Jul 2020

Arcturus and Duke-NUS announce approval of clinical trials for COVID-19 vaccine candidate

Arcturus Therapeutics Holdings Inc., a leading clinical-stage messenger RNA medicines company focused on the discovery, development and commercialization of therapeutics for rare diseases and vaccines, and Duke-NUS Medical School, Singapore's flagship research-intensive graduate entry medical school, today announced that the Clinical Trial Application for COVID-19 vaccine candidate LUNAR-COV19 has been approved to proceed by the Singapore Health Sciences Authority.

22 Jul 2020

SphingoTec introduces a CE-IVD-marked point-of-care test to determine blood levels of bio-ADM

Diagnostics company SphingoTec GmbH today announced the launch of its IB10 sphingotest bio-ADM, a CE-IVD-marked point-of-care test to quantitatively determine blood levels of Bioactive Adrenomedullin (bio-ADM).

22 Jul 2020

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Avacta is pleased to announce that it has begun work with the UK government’s CONDOR program to evaluate and clinically validate the COVID-19 laboratory assay.

22 Jul 2020

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Avacta is pleased to announce that it has begun work with the UK government’s CONDOR program to evaluate and clinically validate the COVID-19 laboratory assay.

22 Jul 2020

High-quality lab procedures crucial to discovery of effective drugs

In their quest to find new drugs to treat deadly diseases, scientists study millions of molecules at high speed at the same time. Often it is enzymes that are investigated as targets in these 'high-throughput' screenings.

21 Jul 2020

Stanford researchers develop a portable device for rapidly detecting blood ammonia levels

Seated around the dinner table, faculty affiliated with Stanford ChEM-H - one of Stanford University's interdisciplinary institutes - spoke one-by-one, pitching ideas for collaborative research.

21 Jul 2020

Early detection of cancer four years before conventional diagnosis using non-invasive blood test

An international team of researchers has developed a non-invasive blood test that can detect whether an individual has one of five common types of cancers, four years before the condition can be diagnosed with current methods. The test detects stomach, esophageal, colorectal, lung and liver cancer.

21 Jul 2020

Promega Maxwell Extraction System added to CDC COVID-19 diagnostic protocol

Promega Corporation’s Maxwell RSC 48 Instrument and Maxwell RSC Viral Total Nucleic Acid Purification Kit are now in the Centers for Disease Control and Prevention’s COVID-19 diagnostic protocol for emergency use.

From Promega Corporation 21 Jul 2020

Antibody profile and estimated seroprevalence in COVID-19 infection

A new Swedish study published on the preprint server medRxiv in July 2020 describes the results of using highly sensitive and specific anti-spike antibody tests in a cohort of patients with COVID-19 over a range of disease severity.

21 Jul 2020

New assay improves detection of SARS-CoV-2 antibodies

Researchers at the University of California Santa Cruz have developed a new assay for the detection of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that they say provides significant advantages over the techniques currently used.

20 Jul 2020

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Promising early stage results from a phase 1/2 clinical trial of the UK's vaccine candidate against SARS-CoV-2 (the virus that causes COVID-19) are published today in The Lancet.

20 Jul 2020

Assay News and Research

Basigin/CD147 discarded as an accessory SARS-CoV-2 binding receptor

Simple blood test may be a great advance for people with and at risk for Alzheimer's

Study identifies phosphorylation-based biomarkers to guide cancer therapy

Population screening has potential to identify individuals at risk for inherited genetic conditions

Study provides insight into evolution of amyloid-β oligomer with temporary salt crystals

Scientists develop COVID-19 test to detect neutralizing antibodies with high sensitivity, specificity

Non-invasive urine test being offered free to the NHS to help clear bladder cancer diagnoses backlog

Exercise equipment in communal gyms have high levels of antibiotic-resistant bacteria

SphingoTec launches point-of-care test for bio-ADM, a biomarker for life threatening endothelial dysfunction

Arcturus and Duke-NUS announce approval of clinical trials for COVID-19 vaccine candidate

SphingoTec introduces a CE-IVD-marked point-of-care test to determine blood levels of bio-ADM

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

Avacta provides update on clinical validation of Adeptrix COVID-19 diagnostic test

High-quality lab procedures crucial to discovery of effective drugs

Stanford researchers develop a portable device for rapidly detecting blood ammonia levels

Early detection of cancer four years before conventional diagnosis using non-invasive blood test

Promega Maxwell Extraction System added to CDC COVID-19 diagnostic protocol

Antibody profile and estimated seroprevalence in COVID-19 infection

New assay improves detection of SARS-CoV-2 antibodies

Oxford University and AstraZeneca vaccine against SARS-CoV-2 safe and induces immune response

Microplate-based assays in microbiology research eBook eBook

How Omics Technologies Are Transforming Biological Research and Drug Discovery

How microplastics and bacteria interact to drive antibiotic resistance

Single-cell proteomics: Revealing proteome diversity from cellular heterogeneity to non-canonical biology

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