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Down syndrome may hold important clues to onset of Alzheimer's disease

At first glance, Down syndrome and Alzheimer's disease, two severe brain abnormalities, may seem to have little in common. Down syndrome is a hereditary disease, the source of which has long been recognized--a triplication of chromosome 21.

17 Oct 2018

Researchers find opportunity to control salt-sensitive hypertension without exercising

Couch potatoes rejoice -- there might be a way to get the blood pressure lowering benefits of exercise in pill form.

16 Oct 2018

Study to explore bioethics of brain organoids

Research scientists around the world are now able to investigate the structural, cellular, and developmental intricacies of the human brain using bioengineered stem cell-based models called organoids.

16 Oct 2018

Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features

A study comparing DNA and RNA data from Nigerian breast cancer patients to patients in a United States database found that certain aggressive molecular features were far more prevalent in tumors from Nigerian women than in black or white American women.

16 Oct 2018

New findings reveal potential cellular players in tumor microenvironment

New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy.

16 Oct 2018

Fish oil based diets may suppress growth and spread of breast cancer cells

Omega-3 fatty acids, such as those typically contained in fish oil, may suppress the growth and spread of breast cancer cells in mice.

16 Oct 2018

Simple, inexpensive test quickly detects antibiotic-resistant 'superbugs'

When you get sick, you want the right treatment fast. But certain infectious microbes are experts at evading the very anti-bacterial drugs designed to fight them.

16 Oct 2018

Study uncovers important role of PRMT1 in dilated cardiomyopathy

In a study published in iScience, Professor Akiyoshi Fukamizu of the Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (University of Tsukuba, JAPAN) and the research group reported a new work on discovery of the important role of PRMT1 in dilated cardiomyopathy.

16 Oct 2018

Zebrafish study uncovers molecular 'brake' that helps control eye lens development

How different cells in a multicellular organism acquire their identities remains a fundamental mystery of development. In the eye, for example, the lens contains two cell types - lens epithelial cells and lens fiber cells -- the first of which differentiates into the second as an animal matures.

16 Oct 2018

Rice University chemist wins big award to study small surfaces

It's one thing to start a chemical reaction and get a result, but it's quite another thing to watch it in progress. Rice University chemist Matt Jones wants to see it happen.

16 Oct 2018

Birth mode may have acute effects on neurodevelopment, study suggests

Cesarean-born mice show altered patterns of cell death across the brain, exhibiting greater nerve cell death than vaginally delivered mice in at least one brain area, a finding by Georgia State University researchers that suggests birth mode may have acute effects on human neurodevelopment that may lead to long-lasting changes in the brain and behavior.

16 Oct 2018

Non-invasive brain stimulation sheds light on neurobiology underlying implicit bias

BIDMC Research Briefs showcase groundbreaking scientific advances that are transforming medical care.

16 Oct 2018

Researchers examine SSRI use during pregnancy and major gestational malformations

A comprehensive new review article presents the most current understanding of the role selective serotonin reuptake inhibitors play in increased risk of multiple diverse gestational malformations and takes aim at the ongoing debate over whether SSRIs as a drug class can cause these malformations.

16 Oct 2018

Research points to potential new treatment for hearing loss

Researchers have taken an important step toward what may become a new approach to restore the hearing loss. In a new study, out today in the European Journal of Neuroscience, scientists have been able to regrow the sensory hair cells found in the cochlea - a part of the inner ear - that converts sound vibrations into electrical signals and can be permanently lost due to age or noise damage.

15 Oct 2018

Modeling Non-Numerical Data in Systems Biology

An interview with Dr. Eshan Mitra, discussing the importance of computer models in biology and the development of a more accurate model of the RAF phosphorylation pathway.

15 Oct 2018

Researchers develop comprehensive molecular atlas of postnatal mouse heart development

Myocardial infarction is one of the most common causes of death in the Western world. Typically, MI is caused by the blockage of a coronary artery by an atherosclerotic plaque: as the oxygen supply of the heart drops, cell death occurs.

15 Oct 2018

Potential 'early warning markers' for sepsis discovered

A multi-site research collaboration supported by a Technology Strategy Board Grant has shown that immune response signatures could be used as an early warning test for the serious condition sepsis in patients attending emergency departments with suspected infection.

15 Oct 2018

Researchers identify basic relationships of cell cycle and cellular senescence in the placenta

Working with researchers from Stanford University and St. Anna Children's Cancer Research, researchers from Jürgen Pollheimer's laboratory at the Medical University of Vienna's Department of Obstetrics and Gynecology have now, for the first time, identified basic relationships of the cell cycle and cellular senescence in the human placenta.

15 Oct 2018

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Squamous cell carcinomas are aggressive malignancies arising from squamous epithelium of various organs, such as esophagus, head and neck, lung and skin. Previous studies demonstrated that two master transcription factors, TP63 and SOX2, effect genomic activation in SCCs.

15 Oct 2018

Researchers demonstrate integrated technique to control production of cell therapeutics

Researchers have demonstrated an integrated technique for monitoring specific biomolecules - such as growth factors - that could indicate the health of living cell cultures produced for the burgeoning field of cell-based therapeutics.

15 Oct 2018

Cell News and Research

Down syndrome may hold important clues to onset of Alzheimer's disease

Researchers find opportunity to control salt-sensitive hypertension without exercising

Study to explore bioethics of brain organoids

Study of Nigerian breast cancer patients reveals prevalence of aggressive molecular features

New findings reveal potential cellular players in tumor microenvironment

Fish oil based diets may suppress growth and spread of breast cancer cells

Simple, inexpensive test quickly detects antibiotic-resistant 'superbugs'

Study uncovers important role of PRMT1 in dilated cardiomyopathy

Zebrafish study uncovers molecular 'brake' that helps control eye lens development

Rice University chemist wins big award to study small surfaces

Birth mode may have acute effects on neurodevelopment, study suggests

Non-invasive brain stimulation sheds light on neurobiology underlying implicit bias

Researchers examine SSRI use during pregnancy and major gestational malformations

Research points to potential new treatment for hearing loss

Modeling Non-Numerical Data in Systems Biology

Researchers develop comprehensive molecular atlas of postnatal mouse heart development

Potential 'early warning markers' for sepsis discovered

Researchers identify basic relationships of cell cycle and cellular senescence in the placenta

Scientists shed light on roles of transcription factors, TP63 and SOX2, in squamous cell carcinoma

Researchers demonstrate integrated technique to control production of cell therapeutics

Industry focus eBook - Cell and gene therapy (2nd edition) eBook

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