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Nanoplastics affect composition and diversity of human intestinal microbiome

We live in a world invaded by plastic. Its role as a chemically stable, versatile and multi-purpose fostered its massive use, which has finally translated into our current situation of planetary pollution.

22 Dec 2020

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

A new study describes the in vitro mechanism by which remdesivir kinetically inhibits the replication of the virus that causes COVID-19, SARS-CoV-2.

18 Dec 2020

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

CN Bio, a leading cell culture company, that has developed single and multi-organ microphysiological systems (MPS) to improve the accuracy and efficiency of drug discovery, today announced a collaboration with the University of Melbourne, focused on respiratory therapies for recovering COVID-19 patients.

18 Dec 2020

A protein may be responsible for triggering lung scarring in scleroderma patients

Systemic sclerosis is an autoimmune disease associated with inflammation and fibrosis, or scarring, that affects organs including the skin, heart, kidney and lungs.

17 Dec 2020

PVP at Boston Children's awarded $1 million to extend research into adjuvant-based vaccines

For a vaccine to be most effective, sometimes nature needs a little 'extra' something. That something is often an adjuvant -- small molecules added to a vaccine that boost the body's immune response.

17 Dec 2020

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a serious chronic disease that affects the tissue surrounding the air sacs in the lungs.

17 Dec 2020

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Researchers from the Washington University School of Medicine, United States of America, recently demonstrated that the SARS-CoV-2 surface proteins alone triggered innate cell activity and the interferon signaling pathway.

17 Dec 2020

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

A recent preprint that appeared on the bioRxiv* server applies a new approach to conventional birth-death lineage modeling.

17 Dec 2020

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

Application of low-intensity pulsed ultrasound in combination with microbubbles might enhance the delivery of chemotherapy medication used for treating cancers.

17 Dec 2020

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

SARS-CoV-2 has infected over 71.5 million people and claimed over 1.6 million lives globally since December 2019.

17 Dec 2020

New screening platform can be used to discover more effective drugs for type 1 diabetes

With nearly 2 million Americans battling type 1 diabetes, it is no surprise that clinical therapies for the disease are constantly evolving and improving.

16 Dec 2020

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Maresin and resolvin, produced by the body from omega-3 fatty acids, can help repair tissue damaged by periodontal disease.

16 Dec 2020

Researchers focus on preventing infections caused by carbapenemase-producing bacteria

In 2017, the World Health Organization published a list of pathogens for which new drugs are urgently needed.

16 Dec 2020

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

As researchers continue to search for antivirals to counter COVID-19, a study presents the potential utility of a decoction called Respiratory Detox Shot (RDS).

16 Dec 2020

Azithromycin trial fails to provide evidence of benefit in COVID-19

Early on in the COVID-19 pandemic, azithromycin was regarded as being a potentially highly effective drug against the virus that causes it, SARS-CoV-2.

16 Dec 2020

Copper gluconate supplementation could reduce SARS-CoV-2 infection in vitro

The second wave of COVID-19 has affected many countries, costing thousands of lives and dealing further heavy blows to already reeling economies.

16 Dec 2020

SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

A new study reveals that the genome of SARS-CoV-2 is inserted into the human genome, accounting for the detection of viral RNAs.

16 Dec 2020

CN Bio and the University of Melbourne collaborate to advance therapies for respiratory complications in recovered COVID-19 patients

From AXT Pty Ltd 16 Dec 2020

RedHill Biopharma announces promising preliminary results from opaganib study

TEL AVIV, Israel and RALEIGH, NC, December 15, 2020, RedHill Biopharma Ltd., a specialty biopharmaceutical company, today announced promising preliminary results from a preclinical study with opaganib.

15 Dec 2020

Xenon positively affects the properties of coatings deposited on titanium implants

Scientists of Tomsk Polytechnic University jointly with the colleagues from Siberian State Medical University (SSMU) and Immanuel Kant Baltic Federal University studied the properties of calcium phosphate coatings deposited on titanium implants in various inert gases environment.

15 Dec 2020

in vitro News and Research

Nanoplastics affect composition and diversity of human intestinal microbiome

Remdesivir inhibits SARS-CoV-2 replication by preventing RdRp-mediated RNA translocation

CN Bio and University of Melbourne announce partnership focused on respiratory therapies for recovering COVID-19 patients

A protein may be responsible for triggering lung scarring in scleroderma patients

PVP at Boston Children's awarded $1 million to extend research into adjuvant-based vaccines

BU researchers awarded $2.4 million NIH grant to study idiopathic pulmonary fibrosis

SARS-CoV-2 surface proteins alter the expression of key chemokines and cytokines in cell lines

Gene surfing caused the SARS-CoV-2 D614G variant to rise to dominance in the US

Low-intensity pulsed ultrasound combined with microbubbles might enhance chemotherapy delivery

Hepatitis C virus drugs synergize with remdesivir against SARS-CoV-2 in vitro

New screening platform can be used to discover more effective drugs for type 1 diabetes

Lipid mediators can enhance regeneration of inflamed periodontal tissue

Researchers focus on preventing infections caused by carbapenemase-producing bacteria

Traditional herbal medicine Respiratory Detox Shot (RDS) inhibits SARS-CoV, SARS-CoV-2 and Influenza A infection in vitro

Azithromycin trial fails to provide evidence of benefit in COVID-19

Copper gluconate supplementation could reduce SARS-CoV-2 infection in vitro

SARS-CoV-2 RNA can be reverse-transcribed to be part of chimeric viral-human genome

CN Bio and the University of Melbourne collaborate to advance therapies for respiratory complications in recovered COVID-19 patients

RedHill Biopharma announces promising preliminary results from opaganib study

Xenon positively affects the properties of coatings deposited on titanium implants

Driving innovation in drug discovery with in vitro biology solutions eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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