Laboratory News and Research

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Stem cells may unlock the secrets to healing the brain

These amazing cells have the remarkable potential to develop into many different cell types in the body and have to potential to revolutionise medical science.

27 Sep 2005

Pulsing heart cell provides clues into how heart disease develops

A pulsing heart cell is giving Oregon Health & Science University researchers insight into how it sends and receives signals, and that's providing clues into how heart disease and other disorders develop.

27 Sep 2005

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Transplantation of insulin-producing pancreatic beta-cells shows great promise as a treatment for type 1 diabetes, but development of this therapy has been hampered by a severe shortage of donor beta-cells, which are obtained from decreased human donors.

26 Sep 2005

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

The relationship between tissue rigidity and tumor formation is fairly well established; however, what is not so well understood is what happens on a molecular level that contributes to such stiffness.

26 Sep 2005

Investing today in the control of the bird flu virus in animals is cheap compared to the costs of a global pandemic that could occur tomorrow

The global strategy for the control of avian influenza in animals remains largely under-funded despite important contributions pledged by some donors, FAO warned today.

26 Sep 2005

Vaccine candidate? Researchers synthesize oligosaccharide from anthrax pathogen

For weeks a white powder caused fear and shock for the American population: a few days after the attacks on September 11th, 2001, four innocent people became the victims of letters that contained the powder - spores of the anthrax pathogen. German researchers have now synthesized a molecule characteristic of anthrax in the laboratory which may be the basis for a new anthrax vaccine.

26 Sep 2005

Set of simple "rules" that nature appears to use to design proteins

By examining how proteins have evolved, UT Southwestern Medical Center researchers have discovered a set of simple "rules" that nature appears to use to design proteins, rules the scientists have now employed to create artificial proteins that look and function just like their natural counterparts.

26 Sep 2005

Scientists reverse memory loss in mice with Alzheimer's

In mice, that had been genetically engineered to develop Alzheimer's disease, scientists were able to reverse the rodents' memory loss by reducing the amount of an enzyme that is crucial for the development of Alzheimer's disease.

26 Sep 2005

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.

26 Sep 2005

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Israeli scientists report in Human Reproduction that they have successfully transplanted whole frozen and thawed ovaries in sheep, retrieved oocytes from these ovaries and triggered them in the laboratory into early embryonic development.

26 Sep 2005

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Neurologix has announced positive interim results of its landmark gene therapy clinical trial for patients with Parkinson's disease. Neurologix's 12-patient, dose-escalating Phase I trial is the world's first study to use a viral vector (the non-pathogenic adeno-associated virus, or AAV) for the treatment of an adult neurological disease.

26 Sep 2005

Study shows that nursing homes should consider diabetes a significant risk factor for falling

Falling is the leading cause of accidental death for elderly people, and a new study from Columbia University Medical Center and NewYork-Presbyterian Hospital/The Allen Pavilion suggests that nursing home residents with diabetes are four times more likely to fall than those who are not diabetic.

26 Sep 2005

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Bacteria-eating cells that generally fight infection may cause dementia in HIV patients, University of Florida and University of California at San Francisco researchers have found.

26 Sep 2005

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Researchers at National Jewish Medical and Research Center have demonstrated that dilute bleach not only kills common household mold, but may also neutralize the mold allergens that cause most mold-related health complaints.

22 Sep 2005

Prediction of new polymorph of the Alzheimer's drug, piracetam

A challenge, presented at last year's e-Science All Hands meeting, has resulted in an e-Science project achieving one of the holy grails of the pharmaceutical industry - the computational prediction of a previously unidentified crystal structure, or polymorph, of a drug molecule.

22 Sep 2005

Botox helps explain possible causes of nerve diseases

Botox, used by Hollywood stars to smooth out facial wrinkles, is playing an important role in UQ research to understand how nerve cells communicate with each other.

22 Sep 2005

John Hopkins scientists uncover "tags" that force proteins to cell surface

Johns Hopkins scientists have discovered internal "shipping labels" that allow -- and perhaps force -- hundreds if not thousands of proteins to get to the surface of cells and stay there.

22 Sep 2005

Next generation of effective viral-based therapies for cancer

Researchers at Columbia University Medical Center continue to make strides in their work to develop the next generation of effective viral-based therapies for cancer.

21 Sep 2005

Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria

...as scientists try to develop new antibiotics faster than the bacteria can evolve new resistance strategies. But now, researchers have a new strategy that may give them a leg up in the race -- reproducing in the lab the natural evolution of the bacterial enzymes that confer resistance.

21 Sep 2005

Students might actually overestimate rather than underestimate their levels of drinking

Numerous studies have shown that misuse of alcohol by college students in the U.S. is a pervasive problem. Most of what is known about consumption levels is based on self-report survey data, which assumes that students are aware of and can accurately calculate how much alcohol they consume.

20 Sep 2005

Laboratory News and Research

Stem cells may unlock the secrets to healing the brain

Pulsing heart cell provides clues into how heart disease develops

Plans to develop a "universal beta-cell line" - treatment for type 1 diabetes

Tumor formation is generated by a complex interaction of both mechanical as well as chemical signals

Investing today in the control of the bird flu virus in animals is cheap compared to the costs of a global pandemic that could occur tomorrow

Vaccine candidate? Researchers synthesize oligosaccharide from anthrax pathogen

Set of simple "rules" that nature appears to use to design proteins

Scientists reverse memory loss in mice with Alzheimer's

Abnormal leakage of lymph fluid from the ruptured lymphatic vessels stimulates the accumulation of fat

Israeli scientists successfully transplant ovaries in sheep and trigger early embryonic development

Neurologix announces positive interim results of gene therapy clinical trial for patients with Parkinson's disease

Study shows that nursing homes should consider diabetes a significant risk factor for falling

HIV-infected macrophages in the brain continuously travel to part of the brain Alzheimer's disease often damages

Dilute bleach neutralizes the mold allergens that cause most mold-related health complaints

Prediction of new polymorph of the Alzheimer's drug, piracetam

Botox helps explain possible causes of nerve diseases

John Hopkins scientists uncover "tags" that force proteins to cell surface

Next generation of effective viral-based therapies for cancer

Antibiotic resistance has put humans in an escalating 'arms race' with infectious bacteria

Students might actually overestimate rather than underestimate their levels of drinking

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